Lidocaine-esketamine infusion reduces movement-evoked pain and opioid consumption in hepatic resection patients
New drug combination reduces pain after liver surgery
This randomized controlled trial of 304 patients undergoing elective hepatic resections found that a lidocaine-esketamine infusion significa…
A new mix of lidocaine and esketamine may lower pain and opioid use for patients recovering from liver surgery during the first three days.
Intrauterine lidocaine significantly reduces pain during IUD insertion in nulliparous and parous women
Lidocaine may reduce pain during IUD insertion for women
This meta-analysis of 651 women found that intrauterine anesthesia (IUA) significantly reduced pain during IUD insertion (SMD -0.47, 95% CI …
A local anesthetic called lidocaine could make the process of inserting an IUD much less painful for women during the procedure.
4% articaine improves anaesthetic success rates compared to 2% lidocaine in children with MIH
Kids' tooth pain: stronger numbing drug works better
This meta-analysis evaluates pharmacological and behavioral interventions for children and adolescents with molar-incisor hypomineralisation…
For kids with MIH, 4% articaine numbs better than 2% lidocaine, easing pain and anxiety during dental work.
Jet lidocaine reduces anxiety during peripheral venous access in meta-analysis of 5 trials
Jet Lidocaine Reduces Anxiety During Blood Draws
A meta-analysis of 5 randomized controlled trials found that jet lidocaine significantly reduces anxiety during peripheral venous access (SM…
A needle-free lidocaine spray may ease anxiety when getting an IV, but it doesn't reduce pain.
Lidocaine cream combined with the Valsalva maneuver shows highest probability of reducing needle puncture pain
Lidocaine and a breathing technique may reduce port needle pain
This network meta-analysis of 942 patients evaluated various interventions for lidocaine effectiveness during TIVAP needle punctures. Lidoca…
A combination of lidocaine cream and a specific breathing technique shows promise in reducing pain for patients during needle punctures.
Intrauterine lidocaine reduces pain during hysteroscope insertion and improves patient satisfaction
Lidocaine reduces pain during hysteroscope insertion
This meta-analysis of nine RCTs found intrauterine lidocaine significantly reduces pain during hysteroscope insertion and at 10 minutes post…
A review of nine trials finds lidocaine instillation cuts pain during hysteroscope insertion and boosts patient satisfaction, but its relief…
Network meta-analysis of sedation strategies in therapeutic gastrointestinal endoscopy shows ketamine-propofol reduces hypoxia and bradycardia versus propofol-opioid
Better Sedation Choices Could Reduce Side Effects During Stomach Tests
This network meta-analysis evaluated pharmacological sedation strategies in 7,071 patients undergoing therapeutic gastrointestinal endoscopy…
Mixing ketamine with propofol lowers breathing and blood pressure risks for patients undergoing long stomach procedures compared to standard…
Liposomal bupivacaine, nerve blocks compared to lidocaine for skin graft donor site pain in burn patients
What's the best way to ease pain after skin graft surgery for burn patients?
A two-phase study (RCT and prospective cohort) in 74 burn patients with <20% TBSA burns compared liposomal bupivacaine injection and preoper…
Burn patients with minor injuries face intense donor site pain after skin graft surgery, but doctors haven't yet reported which numbing meth…
Phase 2 trial compares lidocaine/estradiol cream, nortriptyline, and combination for vestibulodynia subtypes
Can a cream or pill help women with chronic pelvic pain?
A 52-month, phase 2, randomized, double-blinded, placebo-controlled trial in 209 women with distinct vestibulodynia subtypes compared 5% lid…
Women with chronic pelvic pain may finally find relief as a new trial compares creams, pills, and combined treatments to personalize care fo…