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Home › Medications › omega-3 fatty acids

omega-3 fatty acids

5 published articles · Updated continuously

Clinical Trial Landscape

Clinical Trials of omega-3 fatty acids

13 trials tracked of omega-3 fatty acids: 6 in phase 3 or 4 and 4 with published results. The most-cited published study has 231 citations.

13Trials tracked
6Phase 3 & 4
0Recruiting
4With published results
Phase distribution
Phase 4 1 Phase 3 5 Phase 2 5 Other / NA 2
  1. Phase 3 Omega-3 Fatty Acids for Prevention of Post-Operative Atrial Fibrillation Completed · 231 cited
  2. Phase 4 Efficacy and Safety of Alirocumab Versus Usual Care on Top of Maximally Tolerated Statin Therapy in Patients With Type 2 Diabetes and Mixed Dyslipidemia (ODYSSEY DM-Dyslipidemia) Completed · 126 cited
  3. Phase 3 An Efficacy and Safety Study of Alirocumab in Children and Adolescents With Homozygous Familial Hypercholesterolemia Completed · 39 cited
  4. Phase 3 An Efficacy and Safety Study of Alirocumab in Children and Adolescents With Heterozygous Familial Hypercholesterolemia Completed · 33 cited
  5. Phase 3 Effects of Vitamin D and Fish Oil on the Kidney in Hypertensives Completed
  6. Phase 3 Effect of Omega 3 Fatty Acids on Oxidative Stress in HIV Seropositive Patients Completed
Show 7 more trials
  1. Phase 2 An 8-Week Dose-Finding Study to Evaluate the Efficacy and Safety of Alirocumab in Children and Adolescents With Heterozygous Familial Hypercholesterolemia Completed
  2. Phase 2 Omega-3 Fatty Acids for Hyperactivity Treatment in Autism Spectrum Disorder Completed
  3. Phase 2 The Role Of Omega-3 Fatty Acids In Adolescent Depression Completed
  4. Phase 2 Omega-3 Fatty Acids in Adolescent Depression Completed
  5. Phase 2 Omega-3 Fatty Acid Supplementation to ADHD Pharmacotherapy in ADHD Adults With Deficient Emotional Self-Regulation Traits Completed
  6. N/A Omega-3 for Peri- and Postmenopausal Depression Completed
  7. N/A Omega 3 Fatty Acids in the Treatment of Children With Autism Spectrum Disorders Completed

Showing the 13 most-cited and recently-updated of 13 trials. Browse the full registry →

Trial data sourced from ClinicalTrials.gov. Counts describe the research landscape and are not a treatment recommendation. Informational only — not medical advice.

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.
Review of triglyceride-lowering therapies for metabolic dysfunction-associated steatotic liver disease
Drug Pipeline Sys. Review
Review of triglyceride-lowering therapies for metabolic dysfunction-associated steatotic liver disease New Hope for Fatty Liver Disease Targets Hidden Triglyceride Problem
This narrative review synthesizes evidence on triglyceride-lowering therapies for metabolic dysfunction-associated steatotic liver disease. …
• Lowering triglycerides may directly heal fatty liver damage • Helps millions with metabolic syndrome and stubborn liver fat • Most treatme…
Frontiers May 12, 2026
Meta-analysis finds omega-3 and omega-6 PUFAs have limited effect on inflammatory markers
Psychiatry Meta-analysis
Meta-analysis finds omega-3 and omega-6 PUFAs have limited effect on inflammatory markers Omega fatty acids show mixed effects on body inflammation
This meta-analysis of 504 participants examined omega-3 and omega-6 PUFAs supplementation on inflammatory markers. The authors found no sign…
A review of studies found omega supplements may lower one inflammation marker, but most others did not change.
Frontiers May 6, 2026
Omega-3 fatty acids fail to reduce inflammation in hemodialysis patients
Nephrology RCT
Omega-3 fatty acids fail to reduce inflammation in hemodialysis patients Short-term omega-3s did not lower inflammation in dialysis patients
This randomized controlled trial tested omega-3 fatty acids (3 g/day) for 2 months in patients with chronic kidney disease undergoing hemodi…
A trial found that taking omega-3 capsules for two months did not reduce inflammatory markers in patients with chronic kidney disease on hem…
May 1, 2026
Narrative review examines antioxidant metabolites for autism spectrum disorder in children
Drug Pipeline Sys. Review
Narrative review examines antioxidant metabolites for autism spectrum disorder in children Could antioxidant nutrients help children with autism spectrum disorder?
This narrative review evaluates the potential role of antioxidant metabolites from botanical drugs and nutrients, including vitamins E and C…
Antioxidant nutrients like vitamins E and C, plus botanical compounds, may help address oxidative stress linked to autism spectrum disorder …
Frontiers Apr 19, 2026
Omega-3 supplementation reduces stress, anxiety, and depression in Saudi adults over three months
Psychiatry RCT
Omega-3 supplementation reduces stress, anxiety, and depression in Saudi adults over three months Omega-3s Help Calm Stress And Improve Sleep
A randomized, double-blind, placebo-controlled trial in 64 Saudi adults found that omega-3 supplementation (500 mg EPA + 250 mg DHA) signifi…
A new trial shows omega-3 supplements significantly reduce stress, anxiety, and depression while improving sleep and memory in people with s…
Apr 15, 2026