Dostarlimab and Niraparib Combination Improves Progression Free Survival in Advanced Endometrial Cancer
Adding Niraparib to Dostarlimab Delays Endometrial Cancer Worsening
A Phase 3 trial shows that adding niraparib to dostarlimab maintenance significantly extends progression-free survival for patients with adv…
A phase 3 trial found that adding niraparib to dostarlimab after chemo slowed cancer growth in advanced endometrial cancer, but did not exte…
Scoring paclitaxel-coated balloon angioplasty improves 6-month target lesion primary patency by 21.2 percentage points
Paclitaxel coated balloons improve blood flow for dialysis patients
This randomized controlled trial of 219 adults with malfunctioning arteriovenous fistulas or grafts found that scoring paclitaxel-coated bal…
A new balloon technique using a paclitaxel coating helps keep dialysis access sites open longer compared to standard treatments.
Sintilimab may trigger autoimmune GFAP astrocytopathy in esophageal squamous cell carcinoma patients
New cancer treatment may cause rare brain inflammation in patients
This case report and literature review describes a patient with advanced esophageal squamous cell carcinoma who developed autoimmune GFAP as…
A new type of immunotherapy for esophageal cancer can trigger a rare brain condition, requiring doctors to watch for early signs of neurolog…
Paclitaxel arm achieves 56.4% pathologic complete response compared to 23.7% with endocrine therapy
Trial shows chemotherapy helps shrink early breast cancer more effectively
This Phase II multicenter randomized trial evaluated neoadjuvant trastuzumab and pertuzumab combined with either endocrine therapy or paclit…
A new trial compares using standard chemotherapy versus hormone therapy to shrink tumors before surgery in patients with HER2-positive breas…
Drug-coated devices associated with HR 1.86 for wound healing in chronic limb-threatening ischemia
Drug coated devices may help wound healing for limb ischemia
This prospective single-center service evaluation of 341 patients with chronic limb-threatening ischemia found that drug-coated device use w…
New data suggests that using drug coated devices during surgery can lead to more frequent wound healing for people with severe leg blood flo…
SYHX2011 improves objective response rate to 35.8% compared to 25.8% for PAB in breast cancer
Trial shows SYHX2011 improves response rates for breast cancer
This Phase III randomized controlled trial of 459 patients with unresectable locally advanced or metastatic breast cancer found that SYHX201…
A new form of paclitaxel showed higher response rates and fewer skin rashes for patients with advanced or metastatic breast cancer.
Paclitaxel monotherapy shows modest activity in relapsed small cell lung cancer
Nab-paclitaxel shows similar results to paclitaxel for lung cancer
This meta-analysis examined paclitaxel monotherapy in relapsed small cell lung cancer. The 3-month progression-free survival rate was modest…
New data compares two types of paclitaxel treatments for relapsed small cell lung cancer, showing similar safety and effectiveness.
DHP107 noninferior to intravenous paclitaxel in HER2-negative, metastatic breast cancer
Oral paclitaxel shows similar results to IV for breast cancer
This Phase III randomized controlled trial evaluated DHP107 against intravenous paclitaxel in 549 patients with HER2-negative, recurrent or …
A new oral version of a common chemotherapy drug works as well as the standard IV treatment for certain types of advanced breast cancer.
Second-line immunotherapy combination with etoposide and capecitabine improves extracranial disease control in pulmonary choriocarcinoma
New treatment combinations show promise for rare lung cancer
This systematic review and case report analyze 45 cases of primary pulmonary choriocarcinoma. A second-line combination of camrelizumab, eto…
A new combination of immunotherapy and chemotherapy may help control the spread of a rare type of lung cancer called pulmonary choriocarcino…
Immunohistochemical profiling helps differentiate synchronous primary breast invasive carcinoma from metastatic ovarian carcinoma
One woman diagnosed with two different types of cancer simultaneously
This case report and literature review describes a patient with concurrent primary breast cancer and metastatic high-grade serous ovarian ca…
A rare case reveals how one patient can have both breast and ovarian cancer at once, highlighting a complex diagnostic challenge.
THP shows noninferior pCR rates compared to TCbHP in HER2-positive invasive breast cancer
Trial shows omitting carboplatin maintains success in breast cancer
This Phase III randomized controlled trial of 766 women with untreated, stage II and III, HER2-positive invasive breast cancer found that th…
A new clinical trial shows that removing one specific drug can lower severe side effects while maintaining high success rates for certain br…
Signet ring morphology in gastric biopsies may mask metastatic invasive lobular carcinoma from breast cancer
Expert Review Helps Identify Breast Cancer Spreading to Stomach
This case report describes a 52-year-old woman with metastatic invasive lobular carcinoma that was initially misidentified as primary gastri…
A single patient's case shows how specific lab tests can help doctors distinguish between stomach cancer and metastatic breast cancer.