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Patient Mode — summaries use plain language, avoiding clinical jargon.
Rheumatology
Cohort
Lower vitreous CREG1 levels associated with reduced ranibizumab response in diabetic macular edema
Low CREG1 levels may link to poor treatment response
This retrospective cohort study of 189 patients with diabetic macular edema found that lower vitreous CREG1 levels were associated with non-…
New findings suggest that certain protein levels and blood markers might help identify which patients respond to diabetic macular edema trea…
Frontiers
Apr 30, 2026
Rheumatology
Cohort
Ranibizumab plus PRP reduces residual disc neovascularization versus monotherapy in proliferative diabetic retinopathy.
Adding Laser to Eye Injections Cuts Treatment Burden for Diabetic Eye Disease
This retrospective cohort study included 238 patients with proliferative diabetic retinopathy. At 24 months, the combined ranibizumab and pa…
Combining injections with laser treatment for diabetic eye disease significantly reduces future procedures and complications while preservin…
Frontiers
Apr 28, 2026
Ophthalmology
Meta-analysis
Subretinal fibrosis develops in 40-50% of nAMD eyes after 5 years of anti-VEGF therapy, associated with worse vision
How often does scarring develop in treated macular degeneration eyes?
A systematic review and meta-analysis of 58 studies in anti-VEGF-treated nAMD eyes found subretinal fibrosis developed in approximately 10-1…
Scarring in treated macular degeneration eyes affects 10% to 15% within two years and up to half by five years, causing vision loss averagin…
Frontiers
Apr 4, 2026
Drug Pipeline
FDA Approval
FDA Approves Byooviz (ranibizumab) for Neovascular AMD, Macular Edema Following RVO, and Myopic CNV
FDA approves a new eye medicine called Byooviz for three conditions that can cause vision loss.
The FDA has approved Byooviz, a VEGF inhibitor, for intravitreal injection to treat neovascular age-related macular degeneration, macular ed…
FDA approves Byooviz to treat three eye conditions causing vision loss from leaky blood vessels in the retina.
FDA
Apr 2, 2026
Ophthalmology
Meta-analysis
Intravitreal Anti-VEGF Shows Anatomic and Visual Gains in Irvine-Gass Syndrome Meta-Analysis
Can eye injections help people with Irvine-Gass syndrome see better?
A systematic review and meta-analysis of 343 eyes with Irvine-Gass syndrome found intravitreal anti-VEGF treatment was associated with a mea…
Eye injections for Irvine-Gass syndrome reduced swelling and improved vision in most patients, though doctors still need to prove these trea…
Apr 2, 2026
Oncology
Meta-analysis
Meta-analysis: Anti-VEGF biosimilars show equivalent efficacy, safety to reference agents in nAMD
Can cheaper eye drugs work as well as expensive ones? A major review says yes for vision loss in older adults.
A meta-analysis of 17 RCTs (n=6694) found no clinically meaningful differences in BCVA improvement at 12 weeks (MD=-0.42, p=0.17) or endpoin…
Cheaper eye drug copies work just as well as expensive originals for treating vision loss in older adults, a major review confirms.
Mar 30, 2026