Exosomes show promise as biomarkers and therapeutic vectors in diabetic complications
Review suggests exosomes may help target multiple diabetes complications
This narrative review explores the role of exosomes in diabetic kidney disease, retinopathy, and peripheral neuropathy. It highlights their …
A narrative review suggests exosomes might inform strategies to target multiple diabetes complications together, though clinical standardiza…
FDA Approves Pavblu (aflibercept) for Neovascular AMD, RVO, DME, and DR
FDA approves Pavblu to treat several eye conditions that cause vision loss.
The FDA approved Pavblu (aflibercept) for neovascular AMD, macular edema following RVO, DME, and DR. It is a VEGF inhibitor administered by …
The FDA approved Pavblu (aflibercept) for wet age-related macular degeneration, macular edema, diabetic macular edema, and diabetic retinopa…
Systematic review and meta-analysis finds no significant association between diabetic retinopathy and age-related macular degeneration
Diabetic retinopathy and age-related macular degeneration show no significant link
This systematic review and meta-analysis evaluates the association between diabetic retinopathy and age-related macular degeneration.
A meta-analysis found no significant relationship between diabetic retinopathy and age-related macular degeneration, though existing data ha…
High LDL-C to HDL-C ratio linked to cardiovascular events in type 2 diabetes with retinopathy
High cholesterol ratio raises heart risk in diabetics
This post hoc analysis of a randomized controlled trial in 5,006 high-risk type 2 diabetes patients with diabetic retinopathy found that a h…
A routine cholesterol test may reveal hidden heart danger in people with diabetes, even when taking cholesterol drugs.
OCT-A metrics show association with diabetic retinopathy status in cross-sectional study
Eye Scan Spots Diabetes Vision Damage Earlier
This cross-sectional study abstract evaluates the association between OCT-A metrics and diabetic retinopathy status in 108 adult eyes.
A fast, painless eye scan can catch diabetes-related vision damage years before symptoms appear, offering a real chance to save sight before…
Systematic Review Finds Chinese and Western Medicine Combination May Improve Diabetic Retinopathy Outcomes
Chinese Medicine Boosts Eye Care for Diabetics
This systematic review and meta-analysis of 1,127 patients with non-proliferative diabetic retinopathy found that combination therapy with C…
Mixing traditional Chinese medicine with standard Western eye care may help diabetics protect their vision and reduce uncomfortable symptoms…
Meta-analysis finds AI screening tools strongly associated with diabetic retinopathy detection
AI tools show strong link to spotting diabetic eye disease
This meta-analysis of observational and diagnostic studies reports a pooled odds ratio of 5.79 (95% CI: 5.22–6.42) for standalone deep learn…
AI screening tools were linked to better detection of diabetic eye disease in a large review of studies, suggesting they could help identify…
Preclinical deep learning model for diabetic retinopathy screening in low-resource settings
AI Model Spots Diabetic Eye Disease from Smartphone Photos
This preclinical study evaluates an imbalance-aware optimal transport learning approach for diabetic retinopathy detection from smartphone i…
A new AI approach detects diabetic retinopathy from smartphone images with 89% sensitivity, offering hope for low-resource screening.
Meta-analysis links diabetic retinopathy with anxiety and depression in over 383,000 patients
Diabetes Eye Disease and Depression Feed Each Other — and Doctors Are Just Catching On
This meta-analysis synthesizes observational data from 383,195 patients with diabetic retinopathy and/or diabetes mellitus to evaluate the a…
Diabetic eye disease and depression trap patients in a two-way cycle where each condition significantly raises the risk of the other.
Three-parameter online nomogram predicts diabetic retinopathy risk in community-dwelling type 2 diabetes patients
Three Numbers Could Tell Your Doctor If Your Eyes Are at Risk
This retrospective cohort study evaluated a three-parameter online nomogram using diabetes duration, HbA1c, and high BMI (≥24 kg/m²) to pred…
A free, web-based calculator using only your diabetes duration, blood sugar control, and BMI could help doctors spot who needs an urgent eye…
Cross-sectional review of diabetic retinopathy prevalence and risk factors in 384 Somaliland patients
Half of Diabetic Patients at This Hospital Had Eye Damage — and Didn't Know It
This observational, descriptive cross-sectional review examines diabetic retinopathy (DR) prevalence and associated risk factors among 384 p…
Half of diabetic patients at a Somaliland hospital had serious eye damage without knowing it, proving regular screenings are vital for preve…
FDA Approves Eylea HD (aflibercept) for nAMD, DME, Diabetic Retinopathy, and Macular Edema Following RVO
FDA approves a new, higher-dose version of the eye medicine Eylea
The FDA has approved Eylea HD, a VEGF inhibitor, for the treatment of neovascular age-related macular degeneration, diabetic macular edema, …
FDA approves higher-dose Eylea to treat four eye conditions that damage the retina and threaten vision, potentially reducing how often patie…
Research across Diabetic Macular Edema
Related studies from across the Diabetic Macular Edema family.
Intravitreal ziv-aflibercept reduces central macular thickness and improves visual acuity in DME and RVO
Trial shows ziv-aflibercept improves vision in macular edema cases
This systematic review and meta-analysis of 5 RCTs and 8 observational studies found that intravitreal ziv-aflibercept significantly reduced…
A new eye treatment called ziv-aflibercept may help reduce swelling and improve vision for patients with specific types of macular edema.
Narrative review suggests suprachoroidal injections may improve vision and reduce edema in diabetic macular edema
New eye injection method reduces shots and protects vision for diabetics
This narrative review examines suprachoroidal space injections versus conventional intravitreal therapies for diabetic macular edema. The au…
A new injection technique for diabetic eye disease could spare patients from frequent shots and lower the risk of cataracts while improving …
Systematic review and meta-analysis shows aflibercept biosimilars match reference drug efficacy and safety in AMD and DME
Aflibercept biosimilars match the original drug for eye disease treatment
This systematic review and meta-analysis evaluated aflibercept biosimilars versus reference aflibercept for neovascular age-related macular …
A large review of 4064 patients found that aflibercept biosimilars work just as well as the original drug for two common eye conditions.
Aflibercept 8 mg extended dosing maintains visual gains with fewer injections versus 2 mg every 8 weeks in DME
Aflibercept 8 mg every 16 weeks matches standard dosing for diabetic macular edema
This randomized, double-masked, noninferiority phase 2/3 trial enrolled 658 patients aged ≥ 18 years with center-involved diabetic macular e…
A new trial shows that aflibercept 8 mg every 16 weeks works as well as the standard 2 mg every 8 weeks for diabetic macular edema with fewe…
Lower vitreous CREG1 levels associated with reduced ranibizumab response in diabetic macular edema
Low CREG1 levels may link to poor treatment response
This retrospective cohort study of 189 patients with diabetic macular edema found that lower vitreous CREG1 levels were associated with non-…
New findings suggest that certain protein levels and blood markers might help identify which patients respond to diabetic macular edema trea…
Post hoc analysis compares brolucizumab and aflibercept for diabetic macular edema
A New Eye Injection Works Even If You've Had Treatment Before
A post hoc analysis of a randomized trial in 517 participants with diabetic macular edema compared intravitreal brolucizumab to aflibercept …
People with diabetic eye disease who have already tried other injections may still get meaningful vision improvement from brolucizumab.
Subretinal saline injection added to vitrectomy for diabetic macular edema with hard exudates
Does a simple salt solution injection help eyes with diabetic swelling?
A randomized trial in 56 patients with diabetic macular edema and hard exudates compared vitrectomy with subretinal balanced salt solution i…
A simple salt solution injection under the retina helped patients with diabetic eye swelling see better and reduced fluid buildup within sev…
CA-1 levels elevated in aqueous humor of DME patients compared to controls in cross-sectional study
Study finds elevated protein levels in eye fluid of patients with diabetic macular edema
A retrospective cross-sectional study of 74 DME patients and 30 controls found carbonic anhydrase-1 (CA-1) levels in aqueous humor were mark…
Patients with diabetic macular edema have eye fluid protein levels about 10 times higher than those without the condition.
Questions about Diabetic Retinopathy
Can smartphone images be used to screen for diabetic retinopathy in low-resource settings?
Yes, smartphone-based imaging combined with AI screening tools can effectively detect diabetic retinopathy in low-resource settings, though further real-world testing is needed.
Full answer →Does having a high LDL-C to HDL-C ratio increase heart risks if I have diabetic retinopathy?
Yes, a high LDL-C to HDL-C ratio (≥2.0) is linked to a higher risk of cardiovascular events in people with type 2 diabetes and diabetic retinopathy, even when taking statins.
Full answer →How well do AI screening tools detect diabetic retinopathy compared to other methods?
AI screening tools detect diabetic retinopathy with high accuracy, outperforming conventional methods in meta-analyses, but real-world performance varies.
Full answer →Is there a link between having diabetic retinopathy and age-related macular degeneration?
Current evidence shows no significant link between diabetic retinopathy and age-related macular degeneration, despite shared risk factors.
Full answer →