SGLT2 inhibitors reduce risk of diabetic retinopathy progression (rr 0.77) and macular edema progression (rr 0.75)
SGLT2 inhibitors show promise in slowing diabetic eye disease
This meta-analysis of 1,785,409 patients with established diabetic retinopathy (DR) or diabetic macular edema (DME) found that SGLT2i therap…
A large analysis suggests SGLT2 inhibitors may slow the progression of vision-threatening complications in people with diabetes.
Ranibizumab port delivery system shows noninferior BCVA gains and low supplemental treatment requirements in diabetic retinopathy
Ranibizumab port delivery system shows promise for diabetic eye conditions
This meta-analysis evaluates the ranibizumab port delivery system (PDS) for patients with diabetic retinopathy and diabetic macular edema. T…
A new delivery system for ranibizumab shows consistent results for patients with diabetic retinopathy and macular edema.
Photobiomodulation protocol aims to consolidate preclinical evidence for ophthalmic diseases
Planning to Review Light Therapy for Common Eye Diseases and Injuries
This is a protocol for a systematic review and meta-analysis, not a completed study. It outlines plans to evaluate photobiomodulation (PBM) …
Experts are planning a large review to see if light therapy can help treat common eye problems like glaucoma and vision loss.
Diabetic retinopathy is associated with a significantly higher risk of all-cause dementia
Diabetic retinopathy is linked to a higher risk of dementia
This meta-analysis of observational studies involving 2,887,409 patients found that diabetic retinopathy is associated with an increased ris…
A large analysis shows people with diabetic retinopathy may face an increased risk of developing dementia, highlighting the need for closer …
OSAS not significantly tied to diabetic retinopathy overall, but risk doubles in Asian subgroups
Sleep Apnea Link to Diabetic Retinopathy Varies by Region
This meta-analysis of 599,405 patients with type 2 diabetes found no significant overall association between obstructive sleep apnea syndrom…
New data suggests that the link between sleep apnea and eye damage in people with type 2 diabetes depends on location and testing methods.
Dynamic gratings serve as tools for diagnosis and treatment evaluation in neuro-ophthalmic conditions
Dynamic gratings help doctors understand and treat eye conditions
This narrative review explores the use of dynamic gratings, such as phase-alternating oscillation and rapid serial visual presentation, to e…
Moving patterns on a screen, called dynamic gratings, offer new ways to study and treat vision issues like glaucoma and diabetic retinopathy…
Specific gut microbiota taxa are associated with the presence of diabetic retinopathy in T2DM patients
Gut Bacteria Differences Linked to Diabetic Retinopathy in Diabetes Patients
This meta-analysis examined gut microbiota composition and diversity in individuals with Type 2 Diabetes Mellitus and Diabetic Retinopathy. …
Specific changes in gut bacteria are linked to diabetic retinopathy, a serious eye condition affecting people with Type 2 diabetes.
AI-OCT reports reduced false-positive DME referral rates from 69.1% to 24.1%
AI technology reduces unnecessary referrals for diabetic macular edema
This randomized clinical trial evaluated the impact of AI-OCT reports on identifying diabetic macular edema (DME) in patients with diabetes.…
New research shows that adding AI-powered imaging can significantly cut down on false alarms when screening patients for eye issues caused b…
AI diagnostic tools show high accuracy but limited real-world validation in systematic review
Artificial intelligence shows high accuracy in detecting various medical conditions
This systematic review of 24 studies synthesizes evidence on AI and deep learning for disease detection across multiple imaging modalities. …
New analysis of 24 studies shows AI tools can reach over 90% accuracy in spotting everything from lung cancer to skin disorders.
Deep learning models show high sensitivity for identifying various stages of diabetic retinopathy
Deep learning models show high accuracy for diabetic retinopathy grading
This systematic review and meta-analysis of 41 studies evaluates the diagnostic accuracy of deep learning models in grading diabetic retinop…
New analysis shows deep learning tools can accurately identify early signs of vision loss in patients with diabetes.
Fluocinolone Acetonide Implant Shows Reduced Injection Frequency for Diabetic Macular Edema
Fluocinolone Acetonide Implant May Reduce Injection Frequency for DME
A Phase 4 trial shows fluocinolone acetonide implants achieve similar visual outcomes to aflibercept with significantly fewer total injectio…
A new eye implant for diabetic macular edema may significantly reduce the number of monthly injections needed to maintain vision.
miR-29a-3p and miR-204-5p are downregulated in diabetic nephropathy as potential biomarker candidates
Specific MicroRNA Signatures Linked to Type 1 Diabetes Complications
This systematic review and meta-analysis of 9 studies involving 34 contrasts identified specific circulating miRNA signatures associated wit…
Researchers identified specific microRNA signals that may help track kidney and eye damage in patients with Type 1 Diabetes.
Research across Diabetes
Related studies from across the Diabetes family.
Tripterygium glycosides provide renal protective effects in animal models of diabetic nephropathy
Tripterygium glycosides show potential to protect kidneys in diabetes
This meta-analysis of preclinical animal models indicates that tripterygium glycosides (TGs) significantly reduce markers of renal dysfuncti…
New research on animal models suggests tripterygium glycosides may protect kidneys from damage caused by diabetes, but specific dosing is cr…
DEKODE platform protocol aims to improve clinical and process outcomes in diabetic ketoacidosis
New Digital System Aims to Improve Diabetic Ketoacidosis Care
This guideline outlines a study protocol for the DEKODE platform, a cloud-based audit-and-feedback system for managing diabetic ketoacidosis…
A new digital audit system aims to standardize care and improve outcomes for patients experiencing diabetic ketoacidosis in hospital setting…
Press needle and plum-blossom needle combination significantly lowers pro-inflammatory cytokines in diabetic peripheral neuropathy
Acupuncture Techniques May Improve Nerve Function in Diabetic Patients
This randomized controlled trial of 225 patients with diabetic peripheral neuropathy found that press needle embedding combined with plum-bl…
A new trial suggests that specific acupuncture techniques may lower inflammation and improve nerve conduction in people with diabetic periph…
Mass spectrometry identifies 681 differentially expressed proteins in patients with proliferative diabetic retinopathy
Proteomics Analysis Identifies Key Proteins in Diabetic Retinopathy
This meta-analysis of proteomics data using mass spectrometry identified 681 differentially expressed proteins in patients with proliferativ…
New research identifies specific proteins and biological pathways linked to proliferative diabetic retinopathy to help guide future medical …
Higher Triglyceride-glucose index is associated with increased risk of diabetic peripheral neuropathy
High Triglyceride and Glucose Levels Linked to Nerve Damage in Diabetes
This meta-analysis of 32,281 patients with Type 2 Diabetes found that a higher TyG index is associated with an increased risk of diabetic pe…
High levels of fats and sugars in the blood can significantly increase the risk of nerve damage for people with type 2 diabetes.
rs741301 polymorphism is associated with reduced susceptibility to diabetic nephropathy in meta-analysis
Genetic Marker Linked to Lower Risk of Diabetic Kidney Disease
This meta-analysis of 880 individuals with diabetes mellitus and 1008 individuals with diabetic nephropathy found that the rs741301 polymorp…
A specific genetic variation, known as the rs741301 polymorphism, may be linked to a lower risk of developing kidney damage in people with d…
Moxibustion Combination Therapies Improve Nerve Conduction and Clinical Scores in Diabetic Neuropathy
Moxibustion combinations may improve nerve function in diabetic neuropathy
A network meta-analysis suggests moxibustion combined with herbal medicine or acupuncture may improve nerve conduction and clinical scores i…
Combining moxibustion with herbal medicine or acupuncture may improve nerve conduction and scores for people with diabetic peripheral neurop…
Invasive spinal cord stimulation provides variable relief across diverse chronic neuropathic pain conditions
Different types of spinal cord stimulation help various chronic pains
This narrative review synthesizes evidence on invasive spinal cord stimulation (SCS) for various neurological and pain conditions. The autho…
Newer forms of spinal cord stimulation offer promising relief for complex nerve pain and failed back surgeries, but results vary by conditio…
Euonymus alatus may improve glucose metabolism and reduce urinary protein in diabetic nephropathy
Plant extract shows promise in managing diabetes and kidney health
This systematic review of preclinical and clinical data indicates that Euonymus alatus may lower blood glucose, reduce urinary protein, and …
A review of the plant Euonymus alatus suggests it may lower blood sugar and protect kidneys in people with diabetes.
Pharmacist-led medication therapy management improves adherence and glycemic control in a patient with complex T2DM
Pharmacist-led care improves blood sugar for woman with long-term diabetes
This case report describes a single patient with type 2 diabetes who received pharmacist-led medication therapy management. The intervention…
A pharmacist-led review helped a woman with a 30-year history of Type 2 Diabetes significantly improve her medication adherence and blood su…
Intravenous alpha-lipoic acid optimizes symptom relief while oral administration supports structural repair in DPN
Different ways to give alpha-lipoic acid help diabetic nerve pain
This Bayesian network meta-analysis evaluates various alpha-lipoic acid (ALA) administration routes for diabetic peripheral neuropathy. Find…
New data shows that intravenous and oral versions of alpha-lipoic acid offer different benefits for managing symptoms and repairing nerves i…
Microvascular alteration is a statistically significant determinant for diabetic peripheral neuropathy prevalence
New data reveals key drivers of nerve damage in diabetes
This meta-analysis of 83,560 patients across 24 countries identified a global diabetic peripheral neuropathy (DPN) prevalence of 57.42% (95%…
Over half of people with diabetes suffer from nerve damage, but new data highlights specific blood vessel changes as a primary driver of the…
Questions about Diabetic Macular Edema
How does brolucizumab compare to aflibercept for treating diabetic macular edema over time?
Brolucizumab and aflibercept both improve vision in diabetic macular edema, but brolucizumab may allow longer intervals between injections while carrying a higher risk of intraocular inflammation.
Full answer →Are aflibercept biosimilars as safe and effective as the original drug for diabetic macular edema?
Yes, aflibercept biosimilars are as safe and effective as the original drug for diabetic macular edema, based on a systematic review and meta-analysis.
Full answer →Does taking aflibercept every 8 weeks keep vision gains in diabetic macular edema?
Yes, taking aflibercept every 8 weeks maintains vision gains in diabetic macular edema, as shown in a 96-week trial where the 2 mg every 8 weeks regimen kept visual improvements comparable to extended dosing of 8 mg.
Full answer →Is the new drug Pavblu approved for treating diabetic macular edema?
Yes, Pavblu (aflibercept) is FDA-approved for treating diabetic macular edema (DME).
Full answer →Can suprachoroidal injections help improve vision in diabetic macular edema?
Yes, early studies show suprachoroidal injections of triamcinolone can improve vision and reduce swelling in diabetic macular edema, but more research is needed.
Full answer →All Diabetic Macular Edema Articles
- SGLT2 inhibitors reduce risk of diabetic retinopathy progression (rr 0.77) and macular edema progression (rr 0.75)
- Ranibizumab port delivery system shows noninferior BCVA gains and low supplemental treatment requirements in diabetic retinopathy
- Photobiomodulation protocol aims to consolidate preclinical evidence for ophthalmic diseases
- Diabetic retinopathy is associated with a significantly higher risk of all-cause dementia
- OSAS not significantly tied to diabetic retinopathy overall, but risk doubles in Asian subgroups
- Dynamic gratings serve as tools for diagnosis and treatment evaluation in neuro-ophthalmic conditions
- Specific gut microbiota taxa are associated with the presence of diabetic retinopathy in T2DM patients
- AI-OCT reports reduced false-positive DME referral rates from 69.1% to 24.1%
- AI diagnostic tools show high accuracy but limited real-world validation in systematic review
- Deep learning models show high sensitivity for identifying various stages of diabetic retinopathy
- Fluocinolone Acetonide Implant Shows Reduced Injection Frequency for Diabetic Macular Edema
- miR-29a-3p and miR-204-5p are downregulated in diabetic nephropathy as potential biomarker candidates
- High prevalence of microvascular and macrovascular complications among adult Ugandans with diabetes
- Intravitreal ziv-aflibercept reduces central macular thickness and improves visual acuity in DME and RVO
- Exosomes show promise as biomarkers and therapeutic vectors in diabetic complications
- Narrative review suggests suprachoroidal injections may improve vision and reduce edema in diabetic macular edema
- FDA Approves Pavblu (aflibercept) for Neovascular AMD, RVO, DME, and DR
- Aflibercept 8 mg extended dosing maintains visual gains with fewer injections versus 2 mg every 8 weeks in DME
- Systematic review and meta-analysis shows aflibercept biosimilars match reference drug efficacy and safety in AMD and DME
- Systematic review and meta-analysis finds no significant association between diabetic retinopathy and age-related macular degeneration
- Lower vitreous CREG1 levels associated with reduced ranibizumab response in diabetic macular edema
- OCT-A metrics show association with diabetic retinopathy status in cross-sectional study
- High LDL-C to HDL-C ratio linked to cardiovascular events in type 2 diabetes with retinopathy
- Systematic Review Finds Chinese and Western Medicine Combination May Improve Diabetic Retinopathy Outcomes
- Meta-analysis finds AI screening tools strongly associated with diabetic retinopathy detection
- Preclinical deep learning model for diabetic retinopathy screening in low-resource settings
- Three-parameter online nomogram predicts diabetic retinopathy risk in community-dwelling type 2 diabetes patients
- Cross-sectional review of diabetic retinopathy prevalence and risk factors in 384 Somaliland patients
- Meta-analysis links diabetic retinopathy with anxiety and depression in over 383,000 patients
- Post hoc analysis compares brolucizumab and aflibercept for diabetic macular edema
- Subretinal saline injection added to vitrectomy for diabetic macular edema with hard exudates
- FDA Approves Eylea HD (aflibercept) for nAMD, DME, Diabetic Retinopathy, and Macular Edema Following RVO
- CA-1 levels elevated in aqueous humor of DME patients compared to controls in cross-sectional study