OSAS not significantly tied to diabetic retinopathy overall, but risk doubles in Asian subgroups
Sleep Apnea Link to Diabetic Retinopathy Varies by Region
This meta-analysis of 599,405 patients with type 2 diabetes found no significant overall association between obstructive sleep apnea syndrom…
New data suggests that the link between sleep apnea and eye damage in people with type 2 diabetes depends on location and testing methods.
Dynamic gratings serve as tools for diagnosis and treatment evaluation in neuro-ophthalmic conditions
Dynamic gratings help doctors understand and treat eye conditions
This narrative review explores the use of dynamic gratings, such as phase-alternating oscillation and rapid serial visual presentation, to e…
Moving patterns on a screen, called dynamic gratings, offer new ways to study and treat vision issues like glaucoma and diabetic retinopathy…
Specific gut microbiota taxa are associated with the presence of diabetic retinopathy in T2DM patients
Gut Bacteria Differences Linked to Diabetic Retinopathy in Diabetes Patients
This meta-analysis examined gut microbiota composition and diversity in individuals with Type 2 Diabetes Mellitus and Diabetic Retinopathy. …
Specific changes in gut bacteria are linked to diabetic retinopathy, a serious eye condition affecting people with Type 2 diabetes.
AI-OCT reports reduced false-positive DME referral rates from 69.1% to 24.1%
AI technology reduces unnecessary referrals for diabetic macular edema
This randomized clinical trial evaluated the impact of AI-OCT reports on identifying diabetic macular edema (DME) in patients with diabetes.…
New research shows that adding AI-powered imaging can significantly cut down on false alarms when screening patients for eye issues caused b…
AI diagnostic tools show high accuracy but limited real-world validation in systematic review
Artificial intelligence shows high accuracy in detecting various medical conditions
This systematic review of 24 studies synthesizes evidence on AI and deep learning for disease detection across multiple imaging modalities. …
New analysis of 24 studies shows AI tools can reach over 90% accuracy in spotting everything from lung cancer to skin disorders.
Deep learning models show high sensitivity for identifying various stages of diabetic retinopathy
Deep learning models show high accuracy for diabetic retinopathy grading
This systematic review and meta-analysis of 41 studies evaluates the diagnostic accuracy of deep learning models in grading diabetic retinop…
New analysis shows deep learning tools can accurately identify early signs of vision loss in patients with diabetes.
Fluocinolone Acetonide Implant Shows Reduced Injection Frequency for Diabetic Macular Edema
Fluocinolone Acetonide Implant May Reduce Injection Frequency for DME
A Phase 4 trial shows fluocinolone acetonide implants achieve similar visual outcomes to aflibercept with significantly fewer total injectio…
A new eye implant for diabetic macular edema may significantly reduce the number of monthly injections needed to maintain vision.
miR-29a-3p and miR-204-5p are downregulated in diabetic nephropathy as potential biomarker candidates
Specific MicroRNA Signatures Linked to Type 1 Diabetes Complications
This systematic review and meta-analysis of 9 studies involving 34 contrasts identified specific circulating miRNA signatures associated wit…
Researchers identified specific microRNA signals that may help track kidney and eye damage in patients with Type 1 Diabetes.
High prevalence of microvascular and macrovascular complications among adult Ugandans with diabetes
High rates of diabetes complications found in adult Ugandans
This meta-analysis examined the prevalence of various diabetic complications, including neuropathy and retinopathy, in a large cohort of adu…
More than half of Ugandan adults with diabetes suffer from nerve damage, highlighting a critical need for earlier screening and better care.
Intravitreal ziv-aflibercept reduces central macular thickness and improves visual acuity in DME and RVO
Trial shows ziv-aflibercept improves vision in macular edema cases
This systematic review and meta-analysis of 5 RCTs and 8 observational studies found that intravitreal ziv-aflibercept significantly reduced…
A new eye treatment called ziv-aflibercept may help reduce swelling and improve vision for patients with specific types of macular edema.
Exosomes show promise as biomarkers and therapeutic vectors in diabetic complications
Review suggests exosomes may help target multiple diabetes complications
This narrative review explores the role of exosomes in diabetic kidney disease, retinopathy, and peripheral neuropathy. It highlights their …
A narrative review suggests exosomes might inform strategies to target multiple diabetes complications together, though clinical standardiza…
Narrative review suggests suprachoroidal injections may improve vision and reduce edema in diabetic macular edema
New eye injection method reduces shots and protects vision for diabetics
This narrative review examines suprachoroidal space injections versus conventional intravitreal therapies for diabetic macular edema. The au…
A new injection technique for diabetic eye disease could spare patients from frequent shots and lower the risk of cataracts while improving …
Research across Diabetes
Related studies from across the Diabetes family.
Nerve decompressive surgery of the lower limbs reduces pain scores in patients with diabetic peripheral neuropathy
Nerve surgery may reduce pain for patients with diabetic neuropathy
This meta-analysis of 7 trials involving 207 patients found that nerve decompressive surgery of the lower limbs (NDSLL) significantly reduce…
New analysis shows nerve decompression surgery can lower pain scores for some people with diabetic peripheral neuropathy.
Vitamin D supplementation shows low certainty reductions in urinary markers for diabetic kidney disease
Vitamin D shows limited benefit for diabetic kidney disease
This umbrella review meta-analysis evaluates vitamin D and its analogs in patients with diabetic kidney disease. While some reduction in uri…
Vitamin D may lower protein in urine for diabetic kidney disease, but evidence is weak and no benefit for kidney function or survival.
Balanced crystalloids reduce time to DKA resolution by 1.60 hours compared to 0.9% saline
Balanced Crystalloids May Speed Recovery in Pediatric Diabetic Ketoacidosis
This meta-analysis of 320 pediatric patients with diabetic ketoacidosis found that balanced crystalloids significantly reduced the time to D…
A review of data suggests balanced crystalloid fluids may resolve diabetic ketoacidosis faster than standard saline in children.
Early subcutaneous basal insulin plus IV insulin reduces time to DKA resolution by 4.06 hours
Early Subcutaneous Insulin Shortens Recovery Time for Diabetic Ketoacidosis
This meta-analysis of randomized controlled trials evaluated adding early subcutaneous basal insulin to intravenous insulin for adults with …
Adding early subcutaneous insulin to IV treatment can speed up recovery for patients with diabetic ketoacidosis without increasing safety ri…
Immunometabolic dysregulation drives hyperalgesia and hypoesthesia in diabetic peripheral neuropathy
New research explores how inflammation drives nerve damage in diabetes
This narrative review explores the pathophysiology of diabetic peripheral neuropathy, focusing on how hyperglycemia, lipotoxicity, and intes…
Chronic high blood sugar causes more than just high glucose; it triggers a cycle of inflammation and immune stress that damages nerves.
Chronic hyperglycemia causes multi-level nerve damage across the peripheral, autonomic, and central nervous systems
Understanding how high blood sugar damages the entire nervous system in diabetes
This narrative review synthesizes how chronic hyperglycemia impacts the entire neuroaxis in patients with diabetes. It details metabolic and…
High blood sugar can damage nerves throughout the whole body. This affects your senses, movement, and internal organs.
Local antibiotic delivery systems increase healing rates in diabetic foot osteomyelitis compared with control groups in this meta-analysis
Local Antibiotics May Boost Healing in Diabetic Foot Infections
This systematic review and meta-analysis evaluated local antibiotic delivery systems versus control groups for patients with diabetic foot o…
A new analysis suggests local antibiotic delivery may improve healing for diabetic foot bone infections, but more research is needed.
Antibiotic cement achieves 85.2% healing rate in diabetic foot osteomyelitis meta-analysis
Antibiotic cement may help heal diabetic foot infections without major surgery
A systematic review and meta-analysis of 82 patients with diabetic foot osteomyelitis found a weighted healing rate of 85.2% with antibiotic…
A meta-analysis suggests antibiotic-impregnated cement can heal diabetic foot osteomyelitis in most patients, though some still need surgery…
SGLT2 inhibitor use associated with increased diabetic ketoacidosis risk, especially with elevated HbA1c
New review shows SGLT2 drugs raise DKA risk when blood sugar is high
This meta-analysis of observational and randomized trials found SGLT2 inhibitor use is associated with an increased risk of diabetic ketoaci…
A big review of many studies found that medicines for diabetes called SGLT2 inhibitors can increase the chance of a serious condition called…
Perioperative anti-VEGF injections improve vision and reduce bleeding in proliferative diabetic retinopathy
Anti-VEGF injections before eye surgery improve vision and reduce bleeding in diabetic retinopathy
This network meta-analysis evaluated the timing of perioperative anti-VEGF injections for proliferative diabetic retinopathy. Results indica…
A network meta-analysis of 2,646 eyes found that perioperative anti-VEGF injections improved vision and reduced bleeding in patients with pr…
Scoping review maps burden of diabetic emergencies in African healthcare settings
Diabetic emergencies in Africa show wide variation in rates and outcomes
This scoping review synthesizes data from 25 studies regarding diabetic emergencies in Africa. The authors report wide variation in reported…
A review of 25 studies finds diabetic emergencies in Africa vary widely, with high death rates and long hospital stays.
Review of 16 cases shows 25% mortality for pulmonary mucormycosis in DKA patients treated with amphotericin B
Treatment for rare lung infection kills one in four patients with diabetic ketoacidosis
This case report and literature review synthesizes data from 16 patients with diabetic ketoacidosis complicated by invasive pulmonary mucorm…
A review of 16 patients found that one in four died from this rare lung infection. Early diagnosis and surgery are key.
Questions about Diabetic Macular Edema
How does brolucizumab compare to aflibercept for treating diabetic macular edema over time?
Brolucizumab and aflibercept both improve vision in diabetic macular edema, but brolucizumab may allow longer intervals between injections while carrying a higher risk of intraocular inflammation.
Full answer →Are aflibercept biosimilars as safe and effective as the original drug for diabetic macular edema?
Yes, aflibercept biosimilars are as safe and effective as the original drug for diabetic macular edema, based on a systematic review and meta-analysis.
Full answer →Does taking aflibercept every 8 weeks keep vision gains in diabetic macular edema?
Yes, taking aflibercept every 8 weeks maintains vision gains in diabetic macular edema, as shown in a 96-week trial where the 2 mg every 8 weeks regimen kept visual improvements comparable to extended dosing of 8 mg.
Full answer →Is the new drug Pavblu approved for treating diabetic macular edema?
Yes, Pavblu (aflibercept) is FDA-approved for treating diabetic macular edema (DME).
Full answer →Can suprachoroidal injections help improve vision in diabetic macular edema?
Yes, early studies show suprachoroidal injections of triamcinolone can improve vision and reduce swelling in diabetic macular edema, but more research is needed.
Full answer →All Diabetic Macular Edema Articles
- OSAS not significantly tied to diabetic retinopathy overall, but risk doubles in Asian subgroups
- Dynamic gratings serve as tools for diagnosis and treatment evaluation in neuro-ophthalmic conditions
- Specific gut microbiota taxa are associated with the presence of diabetic retinopathy in T2DM patients
- AI-OCT reports reduced false-positive DME referral rates from 69.1% to 24.1%
- AI diagnostic tools show high accuracy but limited real-world validation in systematic review
- Deep learning models show high sensitivity for identifying various stages of diabetic retinopathy
- Fluocinolone Acetonide Implant Shows Reduced Injection Frequency for Diabetic Macular Edema
- miR-29a-3p and miR-204-5p are downregulated in diabetic nephropathy as potential biomarker candidates
- High prevalence of microvascular and macrovascular complications among adult Ugandans with diabetes
- Intravitreal ziv-aflibercept reduces central macular thickness and improves visual acuity in DME and RVO
- Exosomes show promise as biomarkers and therapeutic vectors in diabetic complications
- Narrative review suggests suprachoroidal injections may improve vision and reduce edema in diabetic macular edema
- FDA Approves Pavblu (aflibercept) for Neovascular AMD, RVO, DME, and DR
- Aflibercept 8 mg extended dosing maintains visual gains with fewer injections versus 2 mg every 8 weeks in DME
- Systematic review and meta-analysis shows aflibercept biosimilars match reference drug efficacy and safety in AMD and DME
- Systematic review and meta-analysis finds no significant association between diabetic retinopathy and age-related macular degeneration
- Lower vitreous CREG1 levels associated with reduced ranibizumab response in diabetic macular edema
- OCT-A metrics show association with diabetic retinopathy status in cross-sectional study
- High LDL-C to HDL-C ratio linked to cardiovascular events in type 2 diabetes with retinopathy
- Systematic Review Finds Chinese and Western Medicine Combination May Improve Diabetic Retinopathy Outcomes
- Meta-analysis finds AI screening tools strongly associated with diabetic retinopathy detection
- Preclinical deep learning model for diabetic retinopathy screening in low-resource settings
- Three-parameter online nomogram predicts diabetic retinopathy risk in community-dwelling type 2 diabetes patients
- Cross-sectional review of diabetic retinopathy prevalence and risk factors in 384 Somaliland patients
- Meta-analysis links diabetic retinopathy with anxiety and depression in over 383,000 patients
- Post hoc analysis compares brolucizumab and aflibercept for diabetic macular edema
- Subretinal saline injection added to vitrectomy for diabetic macular edema with hard exudates
- FDA Approves Eylea HD (aflibercept) for nAMD, DME, Diabetic Retinopathy, and Macular Edema Following RVO
- CA-1 levels elevated in aqueous humor of DME patients compared to controls in cross-sectional study