EPA and DHA supplementation significantly lowers inflammatory markers in coronary artery disease patients
Fish oil supplements may lower inflammation in heart disease patients
This secondary analysis of a randomized trial involved 240 patients with stable coronary artery disease on statin therapy. Supplementation w…
A study shows that taking specific fish oils can lower certain markers of inflammation in people with coronary artery disease.
Statin therapy reduces hepatocellular carcinoma risk and hepatic decompensation by 46% in chronic liver disease
Statin Therapy Linked to Lower Risks in Chronic Liver Disease
This umbrella review of systematic reviews analyzed data from 10,515,877 participants to evaluate statin effects on chronic liver disease. T…
A large-scale review suggests statin use may lower the risk of liver cancer and serious complications for people with chronic liver disease.
Evolocumab plus statin protocol targets early neurological deterioration in acute ischemic stroke
New trial plans to test evolocumab for acute ischemic stroke
This randomized controlled trial protocol describes a study of 416 patients with acute ischemic stroke attributable to symptomatic intracran…
A new clinical trial aims to see if adding the drug evolocumab to standard statin treatment helps patients after a stroke.
Shared molecular pathways and hub genes link endocrine disorders with periodontitis progression
Shared Molecular Pathways Link Endocrine Disorders and Periodontitis
This narrative review synthesizes the molecular mechanisms underlying the crosstalk between endocrine disorders and periodntis. It identifie…
New research identifies shared biological pathways that link endocrine disorders with gum disease, potentially changing how doctors treat bo…
General medical management improves medication adherence and lifestyle outcomes in older adults with type 2 diabetes
New management model improves medication use and health for seniors
This randomized controlled trial of 200 older adults with type 2 diabetes and atherosclerotic cardiovascular disease found that a general me…
A new personalized care plan helps older adults with diabetes and heart disease stay on their medications and improve their daily habits.
Statin use and EGFR-TKI efficacy in EGFR-mutant non-small cell lung cancer remains to be evaluated
Statins may boost lung cancer treatment, review planned
This protocol for a systematic review and meta-analysis aims to evaluate if statin exposure is associated with improved outcomes in patients…
A new review will examine if statins improve survival in EGFR-mutant lung cancer patients on targeted therapy.
Multi-target therapies may address combined hypertension and dyslipidemia pathophysiology
Multi-Target Therapies May Address Combined Hypertension and High Cholesterol
This systematic review synthesizes evidence on synergistic mechanisms of hypertension and dyslipidemia, highlighting the RAAS/PPAR axis, AMP…
Combining treatments like statins and RAAS inhibitors may offer a more precise way to manage both high blood pressure and cholesterol levels…
Research in coronary heart disease shows misalignment between investment and clinical guideline priorities
China's heart disease research focuses on bioequivalence, not innovation
This guideline-based research trend analysis of 3,339 publications identifies a significant gap between current research investments and cli…
A review of 3,339 publications shows China's coronary heart disease research heavily emphasizes bioequivalence studies over innovative drug …
Microcirculatory dysfunction during cardiac surgery remains heterogeneous and inconclusive in current clinical evidence
Microcirculation in Cardiac Surgery: What We Know and What Remains Unclear
This narrative review examines microcirculatory dysfunction in patients undergoing cardiac surgery with cardiopulmonary bypass. The authors …
A review of cardiac surgery research shows mixed results on microcirculation, with many gaps between lab findings and patient care.
Statins reduce recurrence risk 23% and mortality in 267,913 HR+ breast cancer patients with HR 0.77
Statins lower recurrence and death risk in hormone receptor-positive breast cancer
This systematic review and meta-analysis evaluated statin use versus non-use in 267,913 patients with hormone receptor-positive breast cance…
A massive analysis of over 267,000 patients shows statins reduce recurrence and death risk in hormone receptor-positive breast cancer.
Favorable adiposity, statins, vitamin D, dried fruit linked to lower ovarian cancer risk in MR meta-analysis
Genetic study links vitamin D, statins to lower ovarian cancer risk
This systematic review and meta-analysis of Mendelian randomization studies found that genetically predicted favorable adiposity, HMG-CoA re…
Genetic evidence suggests vitamin D, statins, and dried fruit may lower ovarian cancer risk, but don't change treatment yet.
Narrative review suggests precision interventions for preeclampsia phenotypes
At-a-Glance
This narrative review examines prevention strategies for preeclampsia in pregnant women. The authors note that standard low-dose aspirin eff…
Preeclampsia prevention is moving beyond aspirin for everyone, with new research showing that matching treatments to a woman's specific risk…