Single-cell RNA sequencing reveals trophoblast and immune mechanisms in preeclampsia pathogenesis
New Sequencing Methods Reveal Hidden Mechanisms of Preeclampsia
This systematic review of single-cell RNA sequencing studies identifies impaired trophoblast differentiation, invasion, and senescence, alon…
Advanced single-cell sequencing reveals how specific cells and molecules contribute to the development of preeclampsia during pregnancy.
Lower HDL, higher LDL, TG, TC linked to preeclampsia risk in meta-analysis
Blood Lipid Levels Linked to Preeclampsia Risk
This meta-analysis of 12 studies found that women with preeclampsia had significantly lower HDL and higher LDL, TG, and TC levels compared t…
Lower HDL and higher LDL, triglycerides, and cholesterol are linked to higher preeclampsia risk, a meta-analysis finds.
Narrative review suggests homocysteine combined with multi-index screening aids early warning for pregnancy complications
Adding homocysteine screening helps spot dangerous pregnancy complications earlier
This narrative review evaluates homocysteine combined with multi-index screening for detecting preeclampsia, fetal growth restriction, gesta…
A review suggests adding homocysteine checks to standard tests helps doctors spot risks like preeclampsia and fetal growth restriction more …
Narrative review suggests precision interventions for preeclampsia phenotypes
At-a-Glance
This narrative review examines prevention strategies for preeclampsia in pregnant women. The authors note that standard low-dose aspirin eff…
Preeclampsia prevention is moving beyond aspirin for everyone, with new research showing that matching treatments to a woman's specific risk…
Critical review links ADMA levels to endothelial impairment in pregnant women with HIV and preeclampsia in sub-Saharan Africa
High ADMA Levels Link HIV And Preeclampsia Risks
This critical review examines the role of asymmetric dimethylarginine (ADMA) in women with both preeclampsia and HIV infection in sub-Sahara…
High ADMA levels block blood flow and link HIV infection to dangerous pregnancy complications like preeclampsia in women.
Narrative review on managing hypertriglyceridemia in pregnancy, including olezarsen and volanesorsen
High Triglycerides In Pregnancy Need New Safe Drug Options Soon
This narrative review synthesizes evidence on hypertriglyceridemia in pregnancy. It covers lifestyle and pharmacologic options, noting trigl…
Pregnant women with very high triglycerides face dangerous risks but safe new drugs are not yet approved for use during delivery.
Study protocol for screening nulliparous women to prevent preeclampsia and fetal growth restriction
A new plan to screen for pregnancy risks is being tested in a UK hospital
This study protocol describes a prospective cohort with a nested randomized controlled trial at Rosie Hospital, Cambridge, UK.
A major research plan is starting to test a new way to screen for preeclampsia and fetal growth restriction in pregnant women.
Systematic review on neuroimmune mechanisms in preeclampsia
Preeclampsia: Why Your Brain Matters More Than You Think
This systematic review synthesizes evidence on neuroimmune mechanisms in preeclampsia.
Scientists are finding that nerve signals play a bigger role in pregnancy high blood pressure than we knew.
Meta-analysis links high early pregnancy TyG index to increased gestational risks across 23 studies
Early Blood Test Could Predict Pregnancy Complications Before They Start
This meta-analysis evaluated 23 studies involving 220,985 participants to assess the relationship between high Triglyceride-Glucose (TyG) in…
Checking blood sugar and fat levels early might help prevent serious pregnancy issues.
Systematic review examines placental biology and social context in Black and African American women with pregnancy complications
The Organ That Records Stress, Racism, and Poverty — Before Birth
This systematic review investigates factors including placental biology, genetic variation, and socioeconomic exposures among Black and Afri…
The placenta records stress, racism, and poverty before birth, shaping higher complication rates for Black women through biology shaped by t…
Placental pathology features associated with preterm delivery and adverse outcomes in singleton pregnancies
Placenta Clues Reveal Why Some Babies Arrive Too Early
An observational review of 3,723 singleton placentas found preterm delivery was associated with lower fetal birth weight, placental weight, …
Doctors now see distinct placenta patterns that explain why some babies arrive too early, helping them understand and prevent preterm labor.
Maternal preeclampsia modestly increases neonatal sepsis risk in infants up to 28 days of age
A Mother’s High Blood Pressure May Raise Her Newborn’s Infection Risk
This systematic review and meta-analysis evaluated 1,513,008 neonates to assess the association between maternal preeclampsia and neonatal s…
Babies born to mothers with preeclampsia face a 27% higher risk of serious infection in the first month of life, prompting doctors to watch …
Questions about Preeclampsia
How do social factors affect preeclampsia in Black and African American women?
Social factors like structural racism, limited healthcare access, and chronic stress increase preeclampsia risk in Black women, interacting with genetic and biological pathways.
Full answer →What neuroimmune mechanisms cause preeclampsia according to recent reviews?
Recent reviews highlight that preeclampsia involves dysregulated neuro-immune-vascular integration, including autonomic dysfunction, neuropeptide signaling, and cerebral autoregulatory failure, alongside classic placental and immune factors.
Full answer →Does a high TyG index in early pregnancy increase preeclampsia risks?
Yes, a high TyG index in early pregnancy is significantly linked to increased preeclampsia risk, based on a large meta-analysis of 23 studies.
Full answer →All Preeclampsia Articles
- Single-cell RNA sequencing reveals trophoblast and immune mechanisms in preeclampsia pathogenesis
- Lower HDL, higher LDL, TG, TC linked to preeclampsia risk in meta-analysis
- Narrative review suggests homocysteine combined with multi-index screening aids early warning for pregnancy complications
- Narrative review suggests precision interventions for preeclampsia phenotypes
- Critical review links ADMA levels to endothelial impairment in pregnant women with HIV and preeclampsia in sub-Saharan Africa
- Narrative review on managing hypertriglyceridemia in pregnancy, including olezarsen and volanesorsen
- Study protocol for screening nulliparous women to prevent preeclampsia and fetal growth restriction
- Meta-analysis links high early pregnancy TyG index to increased gestational risks across 23 studies
- Systematic review on neuroimmune mechanisms in preeclampsia
- Systematic review examines placental biology and social context in Black and African American women with pregnancy complications
- Placental pathology features associated with preterm delivery and adverse outcomes in singleton pregnancies
- Maternal preeclampsia modestly increases neonatal sepsis risk in infants up to 28 days of age
- Systematic review links neutrophil extracellular trap dysregulation to pregnancy complications
- N-acetylcysteine protocol study for early-onset preeclampsia progression in Lagos, Nigeria
- Maternal APOL1 risk alleles show no independent association with preeclampsia risk in multi-ethnic study
- Higher uric acid-to-creatinine ratio linked to preeclampsia risk in advanced maternal age pregnancy