Clinical Trial Search

Primary: Percentage of Trials Correct On Working Memory Test — 87.69; 91.57; 88.01; 91.68 percentage of correct trials — p=>0.05

Primary: Percentage of Participants Completing the Study — 90 Percentage of participants

Primary: Agreement Analysis (Agreement to Reference Standard) - Test Group — 76; 18; 2; 8 Participants

Primary: Physical Functioning Measured Using the Patient-Specific Functional Scale — 7.45; 5.43 score on a scale — p=0.04

Primary: Attention Network Effects

Primary: Absolute Percent Change in Written Naming (Trained Items) — 39.4; 28.4; 33.1; 20.0 absolute percent change

Primary: Change in Alzheimer's Disease Assessment Scale-cognitive Subscale (ADAS-cog) — 2.83 score on a scale — p=0.002

Primary: FCI Score at Follow-up — 147.3; 164.0; 123.3; 150.8 points awarded for correct items

Primary: Number of Participants With a Decline of 6 Points on the Hopkins Verbal Learning Test-Revised (HVLT-R) — 1; 9 Participants — p=.02

Primary: Percentage of Subjects Who Undergo a Hypothetical Change in Clinical Diagnosis and Physician Management Plan After Obtaining a Negative Florbetapir F 18 PET Scan…

Primary: Rivermead Behavioral Memory Test — 11.08; 11.2; 12.31 units on a scale

Primary: Physical Function — -4.7 score on a scale

Primary: Change in the Alzheimer's Disease Assessment Scale-Cognitive (ADAS-Cog) — -0.89; 0.55 score

Primary: Change in Cognitive Performance — 0.8; 0.7; 1.2; 0.4 units on a scale — p=<0.0125

Primary: Change in Mean Global Composite Cognition Score From Baseline — 0.2; 0.2 Z-score — p=0.259

Primary: Link Between Lack of Word and Presbycusis — 38; 38.5; 23; 21.5 score on a scale

Primary: New Occurrence in Dementia Care-A Composite Endpoint Including New Cognitive Diagnoses, Laboratory Investigations Related to Cognitive Impairment, New Dementia…

Primary: Change From Baseline in California Verbal Learning Task Score — 3.04; 5.17; 4.22; 7.04 score on a scale

Primary: Number of Participants With a Diagnosis of a Cognitive Impairment Disorder Measured by Pharmacological Interventions for the Management of Cognitive Impairment. — 0; 0…

Primary: Creyos Cognitive Composite - 3 Month — 0.27; 0.13 Change on z-score — p=0.346

Primary: Percentage of Recruited Subjects Able to Comply With the Protocol — 12; 13; 3; 14 Participants

Primary: Change in Readiness to Engage in ACP (ACP Engagement Scale) — 1.92; 1.54; 2.77; 2.00 units on a scale

Primary: Change in Clinical Dementia Rating Scale - Sum of Boxes (CDR-SB) Score From Baseline — 1.1; .9 score on a scale

Primary: Feasibility of Providing a Neurocognitive Training Program to Elderly Cardiac Surgical Patients - Enrollment — 45 Participants

Primary: Cerebral Metabolic Rate of Oxygen (CMRO2) — 8.17 micro-mol/100g/min

Primary: Change From Baseline on Cognitive Section of Alzheimer Disease Assessment Scale (ADAS-Cog) at Month 6 — -0.24; 0.95 score on a scale — p=0.2

Primary: Quality of Life in Alzheimer's Disease (QOL-AD)--Participants With Dementia (PWD) — 35.42; 38.10; 35.56; 36.12 score on a scale

Primary: Alzheimer's Disease Cooperative Study- Clinical Global Impression Change (ADCS-CGIC) — 3.92; 3.48 scores on the CGIC

Primary: Change in Objective Cognitive Performance Composite z Score — .24; .14 Z score

Primary: Magnetic Resonance Spectroscopy (MRS) Will Measure a Change in Cerebral Energy Function in Brain Tissue — .011; .007; .009; .006 Difference in metabolite amplitude