Narrative review covers diagnostic and treatment strategies for metastatic head and neck cancer with no identifiable primary tumor
Doctors use many tools to treat head and neck cancer when the main tumor is hidden
This narrative review addresses diagnostic and treatment strategies for metastatic cases of head and neck cancer with no identifiable primar…
When head and neck cancer spreads but the original spot is missing, doctors use many tools. Imaging, special tests, and surgery help find th…
Case report suggests grade 3 ICI-induced inflammatory arthritis may correlate with sustained response to tislelizumab in advanced head and neck carcinoma
Could a painful joint flare actually signal that cancer treatment is working long-term?
This case report and literature review describes a single patient with advanced unknown primary carcinoma of the head and neck receiving mai…
A patient with advanced head and neck cancer stayed in complete remission for over a year after joint pain from treatment forced doctors to …
Research across Cancer
Related studies from across the Cancer family.
Egg consumption associated with reduced glioma risk in Eastern populations and increased head and neck cancer risk
Egg consumption shows mixed links to glioma and head and neck cancer
This meta-analysis of observational studies involving 1,274,437 participants found that egg consumption was associated with a reduced risk o…
New data shows a link between egg consumption and lower glioma risk in some groups, but a potential link to higher head and neck cancer risk…
Radiation therapy and nasopharyngeal cancer significantly increase risk of chronic rhinosinusitis in head and neck cancer patients
Head and neck cancer treatments may increase risk of sinus issues
This meta-analysis of 3685 patients identifies a 0.37 pooled incidence of chronic rhinosinusitis in head and neck cancer patients. The analy…
Patients with head and neck cancers face a higher risk of developing chronic sinus inflammation, especially after radiation therapy.
IMRT plus cetuximab does not improve quality of life compared to IMRT plus cisplatin
Trial compares cetuximab and cisplatin for oropharyngeal cancer quality of life
This Phase III randomized controlled trial of 375 patients with p16+ oropharyngeal cancer found no significant difference in quality of life…
A clinical trial found that replacing cisplatin with cetuximab did not improve quality of life or swallowing for patients with oropharyngeal…
Empowered Survivor digital tool boosts self-efficacy in oral cancer survivors
Digital Intervention Improves Self-Care for Oral Cancer Survivors
In a randomized trial of 643 oral/oropharyngeal cancer survivors, the Empowered Survivor digital intervention improved self-efficacy at 2 an…
A new digital program helps oral cancer patients feel more confident and perform more self-care activities like swallowing and mobility exer…
Higher pretreatment HALP score is associated with improved overall survival in head and neck cancer
Higher HALP scores linked to better survival in head cancer
This meta-analysis of 1759 patients found that a higher pretreatment HALP score is associated with improved overall survival (95% CI 0.41-0.…
A new analysis shows that a specific blood score can help doctors predict survival outcomes for patients with head and neck cancer.
C3-derived skeletal muscle index shows strong correlation with L3 index in head and neck cancer
C3 Muscle Index Shows Strong Link to L3 Muscle Levels
This meta-analysis of 2017 patients evaluates the correlation between C3 and L3 skeletal muscle indices in head and neck cancer. The study f…
A new way to measure muscle mass in head and neck cancer patients may offer a simpler, radiation-sparing method for tracking muscle loss.
Malnutrition and sarcopenia are associated with poorer treatment tolerance and higher toxicity in head and neck cancer
Muscle Mass and Nutrition Impact Head and Neck Cancer Care
This narrative review examines the impact of nutritional status, sarcopenia, and body-composition phenotypes on head and neck cancer outcome…
Patients with head and neck cancer may face more complications and lower survival rates if they experience muscle loss or poor nutritional s…
Post-radiotherapy dental extractions increase odds of osteoradionecrosis by 8.38 in head and neck cancer patients
Specific Risk Factors Linked to Jaw Damage After Radiation Therapy
This meta-analysis of 10 studies identifies several risk factors for osteoradionecrosis of the jaws (ORNJ) in patients undergoing head and n…
Certain factors like smoking and dental extractions after radiation are linked to a higher risk of jaw bone damage in head and neck cancer p…
High NLRP-3 Expression Linked to Poor Survival in Solid Cancers
High NLRP-3 levels linked to worse outcomes in solid cancers
Meta-analysis shows high NLRP-3 expression predicts worse overall and disease-free survival in solid tumors, with HR 2.12 for OS.
Higher levels of the NLRP-3 protein are linked to shorter survival times and more advanced disease in several types of solid tumors.
Sarcopenia triples dysphagia odds across cancers, meta-analysis finds
Muscle Loss Linked to Swallowing Problems in Cancer Patients
This meta-analysis of 2,889 patients with cancer, including head and neck cancer, found that tumor-associated sarcopenia is significantly as…
A new analysis finds that cancer patients with muscle loss are nearly three times more likely to have swallowing difficulties, regardless of…
Occupational exposure to asbestos-free talc does not support increased risk of lung or laryngeal cancers
Talc mining workers show higher risk of certain lung cancers
This meta-analysis evaluated the incidence of lung cancer, mesothelioma, and laryngeal cancer among workers exposed to asbestos-free talc. T…
Workers exposed to asbestos-free talc may face a higher risk of lung cancer, though results for other conditions remain uncertain.
Immunonutrition may improve management of radiation-induced oral mucositis in head and neck cancer patients
Immunonutrition may help manage mouth sores in head and neck cancer
This narrative review examines the role of immunonutrition for managing oral mucositis in patients with head and neck malignancies undergoin…
Patients with head and neck cancer often suffer from painful mouth sores. New evidence suggests immunonutrition could help manage these symp…