Research across Liver disease
Related studies from across the Liver disease family.
Precision nutrition offers dynamic optimization for managing patients with chronic liver disease through individualized metabolic profiles
Precision nutrition offers a new way to manage liver disease
This narrative review explores the role of precision nutrition in managing chronic liver disease. The authors argue that tailoring nutrition…
Tailoring nutrition to an individual's unique metabolism could change how doctors manage chronic liver disease and improve patient care.
Periodontitis and chronic liver disease linked through proposed oral-gut-liver axis
Conceptual framework links liver, gut, immune, and oral health
This narrative review proposes a Liver-Gut-Immune-Oral Axis linking periodontitis and chronic liver disease. The authors synthesize mechanis…
A narrative review suggests a conceptual link between liver disease and oral health, though this biological system needs direct experimental…
Combining Pentraxin-3 and AFP increases sensitivity to 0.92 for hepatocellular carcinoma diagnosis in chronic liver disease
New blood test helps doctors find liver cancer earlier with better accuracy than old methods alone
This systematic review and meta-analysis evaluated diagnostic markers in adults with chronic liver disease suspected of hepatocellular carci…
A review of 1,179 patients shows a new marker called PTX3 works well for finding liver cancer. Using both PTX3 and AFP together finds more c…
Narrative review on PCSK9 inhibitors for familial hypercholesterolemia
Review explores PCSK9 inhibitors for familial hypercholesterolemia
This narrative review synthesizes evidence on PCSK9 inhibitors, including evolocumab, for familial hypercholesterolemia. The authors discuss…
This review looks at PCSK9 inhibitors like evolocumab for people with familial hypercholesterolemia. It discusses how these drugs work and t…
Narrative review explores gut microbiota role in postoperative delirium in liver disease
Gut bacteria may help prevent delirium after surgery
This narrative review examines the potential link between gut microbiota alterations and postoperative delirium in older surgical patients w…
A review suggests that gut health could play a role in preventing postoperative delirium in older patients.
Ursodeoxycholic acid reduces ALT and fibrosis in chronic liver disease patients
UDCA Improves Liver Enzymes and Fibrosis in Chronic Liver Disease
This phase IV RCT in 262 patients with chronic liver disease and elevated ALT found that ursodeoxycholic acid 100 mg three times daily for 8…
A phase IV trial found that ursodeoxycholic acid (UDCA) significantly reduced ALT levels and improved fibrosis scores in patients with chron…
Narrative review explores macrophage reprogramming for liver fibrosis and MASH
Scientists explore new ways to reprogram liver cells to heal damaged tissue and stop scarring
This narrative review summarizes macrophage reprogramming strategies for liver fibrosis and MASH. Approaches include gene modulation, pharma…
A recent review looks at fresh methods to change how liver immune cells behave. These changes could help heal liver scarring and improve hea…
Narrative review explores aryl hydrocarbon receptor's dual role in liver injury and protection
Liver's Secret Switch Flips Between Harm and Healing
This narrative review examines the aryl hydrocarbon receptor (AhR) in liver disease. AhR activation drives liver damage through mitochondria…
Your liver has a hidden sensor that pollution can flip to destroy mode but scientists just found how to lock it in repair mode
Systematic review shows high rates of fibrosis and cirrhosis in children with Pi*ZZ alpha-1 antitrypsin deficiency
1 in 4 children with A1AT deficiency develop cirrhosis
This systematic review and meta-analysis examined children with confirmed Pi*ZZ alpha-1 antitrypsin deficiency to assess liver outcomes.
New analysis finds 41% of children with A1AT deficiency have liver fibrosis and 17% have cirrhosis.
Systematic review synthesizes Rhaponticum species chemistry, traditional uses, and research gaps across multiple conditions
Ancient Herbs May Help Modern Health
This systematic review synthesizes data on Rhaponticum species, covering 24 documented species worldwide and their applications for conditio…
Imagine walking through a garden filled with wildflowers.
Narrative review of bile-based traditional Chinese medicines for liver diseases
Bile-Based Medicine May Heal Your Liver, But It Can Also Hurt It
This narrative review examines bile-based traditional Chinese medicines used in the management of liver diseases.
Traditional medicines made from animal bile can help treat liver disease, but they contain a complex mix of helpful and potentially harmful …
Preclinical deep learning framework shows improved dose prediction for unseen cancer sites
A Heavy Burden on Doctors
This is a preclinical development study of a deep learning framework for radiotherapy dose prediction.
A new AI tool can plan radiation doses for many different cancers at once.