Research across Brain Metastasis
Related studies from across the Brain Metastasis family.
NODI parameters ODI and V-ISO differentiate gliomas from brain metastases in contrast-enhancing regions
Brain scan technique helps tell gliomas from metastases
This meta-analysis evaluates the use of Neurite orientation dispersion and density imaging (NODDI) to distinguish gliomas from brain metasta…
A new imaging method may help doctors distinguish between gliomas and brain metastases without invasive biopsy.
ctDNA positivity linked to increased risk of brain metastases in advanced solid tumors
ctDNA in blood and spinal fluid predicts brain metastases risk
This systematic review and meta-analysis of 1763 patients with advanced solid tumors found that ctDNA positivity is associated with a signif…
A new analysis finds that tumor DNA in blood or spinal fluid can signal a higher risk of brain metastases and worse survival.
Local brain therapies associated with reduced mortality in HNSCC patients with brain metastasis
Local brain treatments linked to modest survival gains in rare head and neck cancer cases
This retrospective cohort analysis evaluated 201 patients with head and neck squamous cell carcinoma and brain metastasis from three tertiar…
Local brain treatments linked to lower death risk for rare head and neck cancer patients who develop brain metastases, though most still die…
WBRT shows no significant survival benefit in thyroid cancer brain metastases meta-analysis
Whole-brain radiation shows no clear survival benefit for thyroid cancer brain metastases
A systematic review and individual patient data meta-analysis of 247 patients with thyroid cancer brain metastases found whole-brain radiati…
Whole-brain radiation therapy showed no clear survival benefit for patients with thyroid cancer that spread to their brain.
Adding WBRT to SRS cuts brain metastasis recurrence but raises cognitive decline without survival gain
Adding whole-brain radiation to SRS lowers recurrence but does not extend life for brain metastases patients
This meta-analysis of 1,757 patients with brain metastases found that adding whole-brain radiotherapy (WBRT) to stereotactic radiosurgery (S…
Combining SRS with whole-brain radiation lowers tumor recurrence but does not improve survival compared to SRS alone for patients with brain…
Systematic review examines tumor microenvironment mechanisms in lung cancer brain metastases
New brain strategies target lung cancer before it spreads
This systematic review explores the complex mechanisms driving brain metastasis in patients with lung cancer.
Doctors are finding clever new ways to fight lung cancer that has spread to the brain without breaking the body's natural barriers
Narrative Review Examines Stereotactic Radiotherapy Use in Cancer Patients With Brain Metastases
More Brain Mets? This Radiation Advance Changes Everything
This narrative review examines the role of stereotactic radiotherapy in cancer patients with brain metastases.
Every year, more cancer patients face a terrifying diagnosis: brain metastases.
Retrospective observational study evaluates systemic therapy surveillance in brain metastases patients
Observational study examines MRI surveillance patterns in patients with active brain metastases
This retrospective observational study abstract examines surveillance practices in 33 patients with active brain metastases treated with sys…
Doctors monitoring brain metastasis patients with new drugs found no difference in tumor growth or radiation needs whether they followed gui…
Stereotactic radiation improves symptoms versus hippocampal-avoidance whole brain radiation in patients with 5 to 20 brain metastases
Targeted Brain Radiation Eases Symptoms More Than Full-Brain Treatment
This Phase 3 randomized clinical trial enrolled 196 patients with 5 to 20 brain metastases and no prior brain-directed radiation across four…
Targeted radiation for brain tumors preserves daily functioning and quality of life better than whole-brain treatment in cancer patients wit…
First-line osimertinib shows high response rates in EGFR-mutated NSCLC with active brain metastases
Untreated Brain Metastases Respond Well to Osimertinib
This single-arm phase II trial evaluated first-line osimertinib in 100 patients with EGFR-mutated non-small cell lung cancer, including thos…
Osimertinib, a lung cancer drug, effectively treats untreated brain metastases, with an 81.8% response rate for measurable brain spots in a …
Elevated neutrophil-to-lymphocyte ratio predicts brain metastasis risk in lung cancer patients
Could a simple blood test help find who is most at risk for brain metastasis from lung cancer?
This systematic review and meta-analysis evaluated three immune inflammatory markers in 3,643 participants with lung cancer.
A simple blood test showing high inflammation markers can predict who is most likely to develop brain metastasis from lung cancer.
Hypofractionated stereotactic radiation therapy showed high local control in breast cancer brain metastases
FSRT shows promising results for brain metastases in breast cancer patients
This prospective single-arm phase 2 trial evaluated fractionated stereotactic radiation therapy (FSRT) in 173 patients with breast cancer an…
Fractionated stereotactic radiation therapy kept brain cancer controlled in 88.6% of breast cancer patients after one year with no severe si…
Questions about brain tumor
How does the new framework improve brain tumor MRI analysis accuracy?
New frameworks improve brain tumor MRI analysis by using geometric math to handle missing scans, combining deep learning with data balancing, and standardizing how doctors measure tumor response.
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