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Breast neoplasm

Part of Hormone Receptor-Positive Breast Cancer

1 published article · Updated continuously

Clinical Trial Landscape

Clinical Trials for Breast neoplasm

21 trials tracked for Breast neoplasm.

21Trials tracked
0Phase 3 & 4
0Recruiting
0With published results
Phase distribution
Phase 2 10 Phase 1 2 Other / NA 9
  1. Phase 2 Reversing Hormone Resistance in Advanced Breast Cancer With Pazopanib Completed
  2. Phase 2 Study to Evaluate the Efficacy and Safety of Eribulin Mesylate in Combination With Pembrolizumab in Participants With Metastatic Triple-Negative Breast Cancer (mTNBC) Completed
  3. Phase 2 SV-BR-1-GM in Metastatic or Locally Recurrent Breast Cancer Completed
  4. Phase 2 Comparing Letrozole Given Alone to Letrozole Given With Avastin in Post-Menopausal Women Breast Cancer Completed
  5. Phase 2 Primary Chemotherapy With Docetaxel-Capecitabine and Doxorubicin-Cyclophosphamide in Breast Cancer Completed
  6. Phase 2 Cetuximab and Cisplatin in the Treatment of "Triple Negative" (Estrogen Receptor [ER] Negative, Progesterone Receptor [PgR] Negative, and Human Epidermal Growth Factor Receptor 2 [HER2] Negative) Metastatic Breast Cancer Completed
Show 15 more trials
  1. Phase 2 Neoadjuvant Chemotherapy + Herceptin in HER2 Positive Stage II-III Breast Cancer Patients Completed
  2. Phase 2 Monotherapy With Eribulin In Her2 Negative Metastatic Breast Cancer as a First Line Treatment Completed
  3. Phase 2 A Study to Determine the Activity of Caelyx With Trastuzumab and Docetaxel in the Treatment of Metastatic Breast Cancer (Study P03679) Completed
  4. Phase 2 Phase II Trial to Compare the Safety of Two Chemotherapy Plus Trastuzumab Regimens as Adjuvant Therapy for HER2-positive Breast Cancer (Study P05048) Completed
  5. Phase 1 Pre-operative IRX-2 in Early Stage Breast Cancer (ESBC) Completed
  6. Phase 1 DS-8201a in Patients With Cancer That Tests Positive for Human Epidermal Growth Factor Receptor 2 (HER2) Protein Completed
  7. N/A Prediction of pCR by Preoperative Biopsy in Breast Cancer With cCR After Neoadjuvant Chemotherapy. Completed
  8. N/A Assessing Effectiveness and Implementation of an EHR Tool to Assess Heart Health Among Survivors Completed
  9. N/A Application Of Epirubicin Within A Neo-/Adjuvant Chemotherapy In Patients With Primary Breast Cancer Completed
  10. N/A Effectiveness of Fluoroscopy-guided MLD for Treatment of BCRL Completed
  11. N/A Effectiveness of a Modern Educational Intervention in Breast Cancer Patients Completed
  12. N/A Project Breast47: Effect of an Educational Intervention Completed
  13. N/A A Study to Evaluate Safety and Tolerability in Patients With Metastatic Breast Cancer Receiving Treatment With Caelyx (Study P04878)(COMPLETED) Completed
  14. N/A Exercise Program in Breast Cancer Patients Receiving Neoadjuvant Chemotherapy Completed
  15. N/A Radiofrequency Identification Technology in Locating Non-palpable Breast Lesions in Patients Undergoing Surgery Completed

Showing the 21 most-cited and recently-updated of 21 trials. Browse the full registry →

Trial data sourced from ClinicalTrials.gov. Counts describe the research landscape and are not a treatment recommendation. Informational only — not medical advice.

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.

Research across Hormone Receptor-Positive Breast Cancer

Related studies from across the Hormone Receptor-Positive Breast Cancer family.

Neoadjuvant immune checkpoint inhibitors plus chemotherapy increase pathological complete response in early-stage triple-negative breast cancer
Allergy & Immunology Meta-analysis
Neoadjuvant immune checkpoint inhibitors plus chemotherapy increase pathological complete response in early-stage triple-negative breast cancer Immune checkpoint inhibitors improve response in triple-negative breast cancer
This meta-analysis of 3,377 patients found that neoadjuvant immune checkpoint inhibitors combined with chemotherapy significantly increased …
Adding immune checkpoint inhibitors to chemotherapy helps more patients with early-stage triple-negative breast cancer achieve a complete re…
Chemokine networks regulate triple-negative breast cancer tumor microenvironment but clinical translation remains limited
Oncology Sys. Review
Chemokine networks regulate triple-negative breast cancer tumor microenvironment but clinical translation remains limited Chemokine Targets Show Promise in Lab but Face Clinical Hurdles
This systematic review examines the role of chemokine networks and targeted interventions in the triple-negative breast cancer immune microe…
New research highlights the role of chemokine networks in breast cancer, showing strong results in labs despite challenges in current clinic…
Datopotamab deruxtecan improves progression-free survival to 10.8 months versus 5.6 months in TNBC
OB/GYN & Women's Health RCT
Datopotamab deruxtecan improves progression-free survival to 10.8 months versus 5.6 months in TNBC Trial shows datopotamab deruxtecan improves survival in triple-negative breast cancer
This Phase III randomized controlled trial of 644 patients with untreated, locally recurrent inoperable or metastatic triple-negative breast…
A new trial shows that datopotamab deruxtecan may extend progression-free and overall survival for patients with advanced triple-negative br…
Adenomatoid tumor should be considered in the differential diagnosis for testicular lesions in patients with cryptorchidism
Oncology Sys. Review
Adenomatoid tumor should be considered in the differential diagnosis for testicular lesions in patients with cryptorchidism Testicular Adenomatoid Tumor Linked to History of Cryptorchidism
This case report and literature review describes a 58-year-old man with cryptorchidism, male breast cancer, and thymic B2 thymoma who presen…
A new case report highlights a link between undescended testes and certain benign testicular tumors, helping doctors better identify similar…
Immune checkpoint inhibitors plus chemotherapy improve overall survival in advanced triple-negative breast cancer
Oncology Meta-analysis
Immune checkpoint inhibitors plus chemotherapy improve overall survival in advanced triple-negative breast cancer Immunotherapy plus chemo improves survival in triple-negative breast cancer
This umbrella meta-analysis of 39,147 patients found that combining immune checkpoint inhibitors with chemotherapy significantly improves ov…
Adding immunotherapy to chemo helps some patients with advanced triple-negative breast cancer live longer, but side effects are more common.
Multimodal fusion and radiogenomic frameworks show promise for capturing heterogeneity in triple-negative breast cancer
Oncology Sys. Review
Multimodal fusion and radiogenomic frameworks show promise for capturing heterogeneity in triple-negative breast cancer Artificial Intelligence Shows Promise in Triple-Negative Breast Cancer Care
This narrative synthesis reviews the application of artificial intelligence across radiology, digital pathology, and multi-omics for triple-…
New research shows how artificial intelligence can help identify cancer subtypes and predict treatment responses for patients with triple-ne…
Small intestinal metastasis from triple-negative breast cancer can mimic lymphoma on imaging
Oncology Sys. Review
Small intestinal metastasis from triple-negative breast cancer can mimic lymphoma on imaging Case report: Breast cancer spread to small intestine mimics lymphoma
This case report with literature review describes a patient with triple-negative breast cancer who developed small intestinal metastasis pre…
A breast cancer survivor's anemia was caused by a rare small intestine metastasis that looked like lymphoma on scans.
Datopotamab deruxtecan showed no overall survival benefit versus investigator's choice chemotherapy in metastatic HR-positive breast cancer.
OB/GYN & Women's Health RCT
Datopotamab deruxtecan showed no overall survival benefit versus investigator's choice chemotherapy in metastatic HR-positive breast cancer. Datopotamab deruxtecan extends life for advanced breast cancer patients
This Phase III randomized controlled trial evaluated datopotamab deruxtecan versus investigator's choice chemotherapy in patients with inope…
New drug datopotamab deruxtecan helps advanced breast cancer patients live longer and stay disease-free
Chemo-immunotherapy yields 12-month disease-free status in rare triple-negative neuroendocrine breast cancer
Allergy & Immunology Guideline
Chemo-immunotherapy yields 12-month disease-free status in rare triple-negative neuroendocrine breast cancer A single patient remains disease-free after a new chemo-immunotherapy approach for rare breast cancer
This case report describes a 71-year-old woman with triple-negative neuroendocrine breast cancer treated with paclitaxel, cisplatin, and pem…
A 71-year-old woman with rare breast cancer stayed disease-free for a year using a combination of chemotherapy and immunotherapy that doctor…
Statins reduce recurrence risk 23% and mortality in 267,913 HR+ breast cancer patients with HR 0.77
Oncology Meta-analysis
Statins reduce recurrence risk 23% and mortality in 267,913 HR+ breast cancer patients with HR 0.77 Statins lower recurrence and death risk in hormone receptor-positive breast cancer
This systematic review and meta-analysis evaluated statin use versus non-use in 267,913 patients with hormone receptor-positive breast cance…
A massive analysis of over 267,000 patients shows statins reduce recurrence and death risk in hormone receptor-positive breast cancer.
Immunotherapy improves complete response but lacks overall response benefit in HR+ breast cancer
Oncology Meta-analysis
Immunotherapy improves complete response but lacks overall response benefit in HR+ breast cancer Immunotherapy shows mixed results for hormone-positive breast cancer patients
This systematic review and meta-analysis evaluated immunotherapy in patients with hormone receptor-positive and human epidermal growth facto…
A large analysis found immunotherapy did not improve overall survival but did increase side effects for hormone-positive breast cancer patie…
Trastuzumab deruxtecan improves PFS vs chemotherapy in HR-positive, HER2-low breast cancer
OB/GYN & Women's Health RCT
Trastuzumab deruxtecan improves PFS vs chemotherapy in HR-positive, HER2-low breast cancer Trial shows T-DXd beats chemo for breast cancer
In a phase 3 RCT of 866 patients with HR-positive, HER2-low/-ultralow metastatic breast cancer after endocrine therapy, trastuzumab deruxtec…
A new drug, T-DXd, helps people with a common type of advanced breast cancer live longer without their disease getting worse.