Edoxaban monotherapy reduces adverse events compared to dual therapy in patients with atrial fibrillation and coronary artery disease
One Blood Thinner May Be Safer Than Two for Heart Rhythm Patients
This secondary analysis of a randomized clinical trial evaluated 1,040 patients with atrial fibrillation and stable coronary artery disease.
Taking just one blood thinner instead of two cuts the risk of death, stroke, or bleeding for heart patients with irregular rhythms.
Left bundle-branch pacing reduced death or heart failure hospitalization compared with biventricular pacing in heart failure with left bundle-branch block
Left bundle-branch pacing reduced death or hospitalization compared to biventricular pacing in heart failure patients
This randomized clinical trial enrolled 200 patients at six centers in China with heart failure, left bundle-branch block, and an LVEF of 35…
Left bundle-branch pacing cuts heart failure hospitalizations by 70% compared to standard biventricular pacing in patients with severe heart…
Conduction system pacing showed inferior outcomes compared to biventricular pacing in adults with heart failure and left bundle-branch block
New Brazil study found conduction system pacing was inferior to biventricular pacing for heart failure patients
This randomized clinical trial enrolled 173 adults with symptomatic heart failure with reduced ejection fraction and left bundle-branch bloc…
A new Brazil trial found conduction system pacing was worse than standard biventricular pacing for heart failure patients, increasing risks …
HFpEF probability scores rule out disease but show limitations in AF and obesity phenotypes
HFpEF probability scores work well for typical cases but struggle with atrial fibrillation and obesity
This systematic review evaluated the performance of HFpEF probability scores (HFA-PEFF and H2FPEF) in patients with heart failure with prese…
Heart failure scores work well for typical cases but lose accuracy in patients with atrial fibrillation or obesity due to altered biological…
In CRT recipients with persistent AF, rhythm control improved LVEF compared to rate control strategies
Does fixing your heart rhythm actually improve pump function in this specific group?
This randomized trial evaluated rhythm versus rate control strategies in 43 CRT recipients with long-standing persistent AF and low biventri…
Fixing irregular heartbeats boosted heart muscle strength in patients with devices, but daily life and exercise ability improved similarly w…
Catheter ablation reduces cardiovascular risk in atrial fibrillation with normal left atrial diameter but not in enlarged atria
Atrial fibrillation ablation benefits vary by heart size in large trial
This randomized controlled trial evaluated 1130 patients with atrial fibrillation who underwent baseline echocardiographic measurement of le…
Patients with normal-sized hearts gain the most life-saving benefit from atrial fibrillation ablation compared to those with enlarged hearts…
Elevated soluble ST2 predicts atrial fibrillation development and recurrence after catheter ablation in 14,582 participants
High sST2 levels linked to higher risk of atrial fibrillation and recurrence
This systematic review and meta-analysis of 19 studies involving 14,582 participants examined the association between soluble ST2 (sST2) lev…
High blood levels of a protein called sST2 signal a greater risk of developing atrial fibrillation and its return after heart treatment.
Combined LAPVI improved sinus rhythm maintenance versus PVI alone in persistent AF patients
Combined Ablation Technique Improves Rhythm Control in Persistent Atrial Fibrillation Patients
This randomized controlled trial evaluated 228 patients with persistent atrial fibrillation comparing combined Left Atrial Posterior Wall Li…
Adding a specific linear ablation to standard heart surgery helps 75% of persistent atrial fibrillation patients maintain normal rhythm comp…
Post-hoc analysis links lower systolic BP to higher cardiovascular risk in AF and stable CAD
Lower blood pressure linked to higher risk in AF patients with heart disease
A post-hoc analysis of the AFIRE trial (n=2135) found patients with atrial fibrillation and stable coronary artery disease who had baseline …
Patients with atrial fibrillation and low blood pressure face a 38% higher risk of heart attack, stroke, or death compared to those with hig…
Indirect comparison suggests Sphere-9 PFA catheter may have higher efficacy than Farawave for persistent AF
Two pulsed field ablation systems compared indirectly for persistent atrial fibrillation
A matched-adjusted indirect comparison of two pulsed field ablation (PFA) systems for symptomatic persistent atrial fibrillation found the S…
Patients treated with the Sphere-9 pulsed field ablation system had a 77.4% success rate at 12 months, compared to 63.5% for the Farawave sy…
DOACs show varied efficacy and safety profiles versus VKAs in atrial fibrillation patients with fall risk
Study compares blood thinners for atrial fibrillation patients with fall risk
A Bayesian network meta-analysis of 10 studies (5 RCTs, 5 observational) in AF patients with fall history/risk found apixaban ranked highest…
For atrial fibrillation patients at risk of falling, apixaban best prevents strokes while edoxaban best lowers major bleeding risks compared…
Left atrial appendage closure fails noninferiority test versus medical therapy in high-risk AF patients
Study finds device for stroke prevention in atrial fibrillation not as effective as medical therapy
A multicenter RCT in Germany randomized 912 high-risk AF patients to catheter-based left atrial appendage closure or physician-directed best…
A new German study found that a heart device to prevent strokes in atrial fibrillation was not as effective as standard blood-thinning medic…