Research across Respiratory Failure
Related studies from across the Respiratory Failure family.
Multidisciplinary decision-making and structured protocols are essential for ECMO withdrawal in cardiac and respiratory failure
Experts Identify Need for Better ECMO Withdrawal Protocols
This narrative review examines the complexities of ECMO withdrawal for patients with cardiac and respiratory failure. The authors emphasize …
New insights highlight the need for better communication and structured plans when deciding to stop ECMO for patients with heart or lung fai…
Evaluating Carbocisteine and Hypertonic Saline for Management of Acute Respiratory Failure
Trial shows two common treatments do not shorten ventilator time
A large multicenter trial indicates that neither carbocisteine nor hypertonic saline reduces ventilation time, while both increase specific …
A large trial found that adding specific medications did not help patients breathe on their own sooner and may have caused side effects.
Telemedicine Intervention Impacts Spontaneous Breathing Trial Frequency and Ventilation Duration
Telemedicine helps ICU patients breathe on their own faster
A stepped-wedge cluster-randomized trial suggests telemedicine rounding significantly increases spontaneous breathing trials in ICU patients…
A new analysis shows that telemedicine rounds can help ICU patients spend less time on breathing machines and try to breathe on their own mo…
Short mechanical ventilation after successful spontaneous breathing trials may reduce reintubation risk in critically ill adults
Short Ventilation Period May Help Prevent Reintubation in Critically Ill Adults
This meta-analysis of 1071 patients evaluated whether a short period of invasive mechanical ventilation following a successful spontaneous b…
A short period of mechanical ventilation after a successful breathing trial may help prevent the need for reintubation in critically ill pat…
NIV with total face mask managed acute respiratory failure in two patients with Madelung's disease and COVID-19 pneumonia
Non-invasive ventilation may help patients with Madelung's disease and respiratory failure
This case series describes non-invasive ventilation using a total face mask in two patients with Madelung's disease who experienced acute re…
A small case series suggests non-invasive ventilation can manage acute respiratory failure in patients with Madelung's disease, though more …
Conservative oxygen targets show no mortality difference in mechanically ventilated critically ill adults
New Oxygen Rules Save Lives Without Extra Risk in ICU
This systematic review and meta-analysis of 20,447 mechanically ventilated critically ill adults in the ICU found no substantial difference …
ICU teams can safely use less oxygen for ventilated patients, new research shows, potentially reducing harm without raising death risk for m…
Endoscopic Guidance Does Not Reduce Complications in Tracheostomy
At-a-Glance
In a multicenter RCT, endoscopic-guided percutaneous tracheostomy did not lower perioperative complications compared to nonendoscopic guidan…
A major trial found that using a camera to guide a breathing tube surgery in ICU patients offered no safety advantage over the standard proc…
Feasibility trial protocol for ultrasonography-guided therapeutic pleural drainage in ICU patients with pleural effusion and respiratory failure
A new trial protocol checks if ICU drainage helps adults with fluid buildup and breathing trouble
This feasibility trial protocol evaluates ultrasonography-guided therapeutic pleural drainage with small-bore catheter in adults acutely adm…
This feasibility trial protocol checks if draining fluid from the lungs helps adults in the ICU who have breathing trouble and fluid buildup…
Dataset describes continuous monitoring in premature VLBW infants across four US NICUs
Heart rate and oxygen data tracked in premature infants
This dataset description covers continuous heart rate and oxygen saturation monitoring in 3,829 premature very low birth weight infants acro…
A new dataset tracks continuous heart rate and oxygen levels in 3,829 premature infants to improve care.
Machine learning models outperformed APACHE-II for predicting mortality in severe community-acquired pneumonia patients with respiratory failure
Machine learning models may predict pneumonia death risk better than standard scores in ICU patients
This retrospective cohort study evaluated machine learning models versus the Acute Physiology and Chronic Health Evaluation II (APACHE-II) s…
New computer models predict pneumonia death risk in ICU patients more accurately than standard scores doctors currently use.
Machine learning models predict noninvasive support failure in acute respiratory failure with moderate accuracy
AI Predicts Breathing Trouble, But Can We Trust It Yet?
A systematic review and meta-analysis of 34,500 adults with acute respiratory failure found machine learning prediction models had a pooled …
A new computer program predicts breathing tube failure with 84% accuracy, but doctors must decide if this tool is ready to save lives.
Multi-component environmental control intervention shows feasibility for sleep promotion in ventilated ICU patients
Small pilot study tests sleep environment intervention for ventilated ICU patients
A pilot randomized controlled trial in 17 mechanically ventilated ICU patients with minimal sedation assessed the feasibility of a multi-com…
A small Chilean ICU study shows that dynamic lights, sound masking, and grouped care checks are feasible ways to help ventilated patients sl…