Hepatologist-led palliative care matches specialist care for cirrhosis and cancer patients
Trained liver doctors provided care that matched specialists for patients with serious liver disease
A US trial found hepatologist-delivered palliative care noninferior to specialist care for improving quality of life in advanced liver disea…
Patients with advanced liver disease saw similar quality of life improvements when cared for by trained liver doctors versus specialists. Bo…
L-taurine shows no overall fatigue benefit in decompensated cirrhosis but may help non-anemic patients
Taurine for cirrhosis fatigue fails overall but helps one group
This randomized controlled trial in 220 adults with decompensated cirrhosis found no significant difference in fatigue scores with L-taurine…
Taurine did not reduce fatigue in most cirrhosis patients, but those without anemia saw meaningful improvement, suggesting a targeted approa…
Influenza vaccine induces stronger immune responses in liver cirrhosis patients
Flu Shot Works Better in Advanced Liver Disease
This prospective observational study found that patients with liver cirrhosis mount stronger humoral and cell-mediated immune responses to t…
You’re living with cirrhosis. Every cold feels dangerous.
Nurse-assisted outpatient follow-up reduces 30-day readmissions but not mortality in decompensated cirrhosis
Nurse Care Cuts Hospital Returns for Liver Patients
A meta-analysis of 668 patients with decompensated liver cirrhosis found nurse-assisted outpatient follow-up significantly reduced 30-day re…
Adding nurses to liver care teams significantly cuts 30-day hospital readmissions and improves outcomes for patients with advanced liver dis…
First-in-human study finds VS-01 generally well tolerated in decompensated cirrhosis with ascites
Early safety study of VS-01 infusion in 12 patients with advanced liver disease
This phase 1b, open-label, non-randomized study in 12 patients with decompensated cirrhosis, ascites, and covert hepatic encephalopathy foun…
A new liver treatment called VS-01 was safe for patients with advanced disease, causing mostly mild stomach issues in an early study of 12 p…
Novel nomogram predicts long-term survival after TIPS in decompensated cirrhosis
Can we better predict survival for cirrhosis patients getting TIPS treatment?
A retrospective single-center cohort study of 409 patients with decompensated cirrhosis undergoing first TIPS developed and validated a nomo…
A new prediction tool outperforms standard scores at estimating how long patients with advanced liver disease will survive after a major shu…
Research across Cirrhosis
Related studies from across the Cirrhosis family.
Dioscin shows therapeutic potential for various liver disorders including MASLD and hepatocellular carcinoma
Plant Compound Dioscin Shows Promise For Liver Disease
This systematic review evaluates the hepatoprotective effects and pharmacokinetics of Dioscin in various liver diseases. The review conclude…
A plant compound called Dioscin may help protect the liver, but human evidence is still missing and high doses carry risks.
Prolonged SEMS retention for refractory variceal bleeding allows removal after 387 days
Doctors successfully remove a metal stent after one year of use
This case report describes a 72-year-old woman with decompensated cirrhosis who received a fully covered self-expanding metal stent (SEMS) f…
A new case report shows a metal stent can be safely removed after a year of use, offering a possible path for patients with liver disease.
Multidrug-resistant pathogens are prevalent in cirrhosis with higher rates in lower-middle-income countries
Gram-negative Bacteria and Resistance Patterns in Cirrhosis Patients
This systematic review and proportional meta-analysis of 2781 clinical infections and 381 colonizations in adults with cirrhosis identifies …
A large review of infections in patients with cirrhosis shows that 60% of bacterial isolates are Gram-negative and many show drug resistance…
Non-selective beta-blockers reduce mortality risk by 25% in patients with decompensated cirrhosis
Beta Blockers May Reduce Mortality Risk in Cirrhosis Patients
This meta-analysis of observational studies involving 120,072 patients found that non-selective beta-blockers (NSBBs) are associated with a …
A large-scale review suggests that non-selective beta-blockers may lower mortality risks for patients with decompensated cirrhosis, especial…
Sarcopenia Assessment Modalities and Mortality Risk Prediction in Patients with Liver Cirrhosis
Muscle Loss Linked to Higher Mortality Risk in Liver Cirrhosis
Meta-analysis confirms that sarcopenia significantly increases mortality risk in liver cirrhosis patients across multiple imaging and physic…
Patients with liver cirrhosis and muscle loss, known as sarcopenia, face a significantly higher risk of mortality across several different m…
Multidisciplinary teams and bloodless medicine pathways may improve outcomes for acute gastrointestinal bleeding
New research looks at better ways to treat internal bleeding
This systematic review synthesizes evidence on organizational models, such as multidisciplinary team programs and transfusion-free pathways,…
Specialized team-based care and bloodless medicine pathways show promise for patients with serious gastrointestinal bleeding.
Direct oral anticoagulants reduce thrombotic events and major bleeding in cirrhosis with atrial fibrillation or venous thromboembolism
Direct oral anticoagulants show promise for patients with liver cirrhosis
A meta-analysis of predominantly observational studies compared direct oral anticoagulants with traditional anticoagulants in patients with …
New analysis suggests direct oral anticoagulants may reduce blood clots and major bleeding risks for patients with liver cirrhosis and heart…
Multidrug-resistant bacterial infections are prevalent among hospitalized patients with cirrhosis
Analysis shows high rates of drug resistant infections in cirrhosis
This meta-analysis examined the prevalence of multidrug-resistant bacterial infections in hospitalized patients with cirrhosis. The findings…
Over one-third of hospitalized patients with liver cirrhosis face infections from bacteria that are hard to treat with standard medications.
Carvedilol and endoscopic variceal ligation show similar efficacy for preventing variceal bleeding in cirrhosis
Comparing Carvedilol and Endoscopic Procedures to Prevent Bleeding in Liver Cirrhosis
This meta-analysis of randomized controlled trials involving 1385 patients found no significant difference between carvedilol and endoscopic…
Doctors are looking at whether the drug carvedilol works as well as endoscopic procedures to stop dangerous bleeding in patients with liver …
Viscoelastic Testing Cuts Transfusions in Cirrhosis Procedures
New testing method reduces blood transfusions for liver patients
Meta-analysis finds VET-guided transfusions reduce blood product use without raising bleeding risk in cirrhotic patients undergoing procedur…
A new testing method helps patients with cirrhosis receive fewer blood transfusions during invasive procedures without increasing their risk…
Exercise programs improve muscle mass and physical performance indicators in patients with liver cirrhosis
Exercise improves muscle strength in cirrhosis patients
This meta-analysis of 16 studies involving 942 patients found that exercise interventions significantly improved 6-min walk distance, thigh …
Exercise boosts muscle mass and walking ability in people with cirrhosis and muscle loss, a new analysis finds.
Tryptophan metabolism pathways like IDO and TDO2 influence immune cell function in end-stage liver disease
New research explores how liver enzymes impact transplant immunity
This systematic review examines the role of tryptophan metabolism, specifically the kynurenine pathway and AhR signaling, in immune toleranc…
Scientists are looking at how specific pathways in the body might help patients with end-stage liver disease accept transplants.