Research across Depression
Related studies from across the Depression family.
Yoga with education yields clinically relevant improvements for depressive symptoms and pain in chronic low back pain
Yoga and Education Show Promise for Back Pain and Depression
This meta-analysis evaluates interventions for individuals with comorbid depressive symptoms and chronic nonspecific low back pain. Yoga wit…
A review of 834 patients suggests that yoga combined with education may improve both chronic back pain and depressive symptoms.
Atractylenolide III shows neuroprotective effects in preclinical CNS disorder models
Atractylenolide III shows promise for brain and nerve injuries in lab models
This narrative review summarizes preclinical evidence that Atractylenolide III exerts neuroprotective effects in models of cognitive impairm…
Atractylenolide III looks like a helpful option for brain and nerve damage in early lab tests, though human trials are needed.
Frailty is associated with increased prevalence of depressive symptoms in adults with cancer
Frailty strongly linked to depression in cancer patients
A meta-analysis of cross-sectional studies examined the relationship between frailty and depression in adults with cancer.
Frail cancer patients are nearly six times more likely to struggle with depression, a major red flag for care teams and families.
MDD polygenic scores show adolescence-specific effects on child depressive symptoms in Norwegian cohort
Teen Depression Linked to Genes That "Switch On" at Puberty
This cohort study of children from the Norwegian Mother, Father and Child Cohort assessed depressive symptoms at ages 8 and 14.
Your teen's depression risk may be written in their genes, but only becomes visible during puberty's hormonal storm.
Prenatal parabens exposure linked to adverse pregnancy outcomes in mothers with depressive symptoms in Ningxia, China
Depression Makes Chemicals Worse for Babies
This prospective cohort study of 934 mother-infant pairs in Ningxia, China, examined associations between prenatal parabens exposure and adv…
Mental health and chemical exposure work together to hurt pregnancy outcomes more than either one does alone.
GP psychoeducation sessions show no significant effect on depressive symptoms in primary care patients
Brief German study shows GP-led sessions improved patient knowledge and activation, but did not significantly reduce depressive symptoms
A cluster-randomized controlled trial of 121 primary care patients with depressive symptoms found that four individual psychoeducation sessi…
A German study found that general practitioner-led sessions improved patient knowledge and engagement, though they did not significantly red…
Pharmacogenomic-guided treatment showed age-dependent cognitive benefits in depressive disorder patients
Can a Cheek Swab Pick the Right Antidepressant for You?
This single-center randomized controlled trial enrolled 843 patients with depressive disorder stratified by age.
A DNA test that guides antidepressant choice lifted mood and sharpened thinking in young patients, but gave almost no brain-function boost t…
AI CBT chatbot access reduces anxiety and depression symptoms in Brazilian primary care patients
Could a chatbot ease anxiety for patients near a specific care threshold?
A quasi-experimental study of 43,287 primary care patients in Brazil found that access to an AI-powered CBT chatbot causally reduced PHQ-ADS…
Patients near a care threshold who used an AI chatbot saw real improvements in anxiety and depression over 12 weeks in Brazil.
P50 sensory gating deficits linked to depressive symptoms in adolescents with non-suicidal self-injury
Brain signal differences found in teens who self-harm and have depression
An observational study of 86 adolescents with NSSI and 50 healthy controls found P50 sensory gating deficits (higher S2/S1 ratio and S2 ampl…
Teens who self-harm and feel depressed show weaker brain signals that make it harder to filter out repeated sounds.
Telehealth CBT improves quality of life in veterans with Parkinson's disease and comorbid depression
Telehealth therapy improved quality of life for veterans with Parkinson's and depression
In a randomized controlled trial of 90 veterans with Parkinson's disease and primary depressive disorders, telehealth-delivered PD-informed …
Veterans with Parkinson's and depression who used video therapy saw better physical and mental quality of life compared to standard care.
Anxiety and depressive symptoms increased among U.S. adults during the COVID-19 pandemic
Anxiety and depression symptoms increased among U.S. adults during the pandemic
An observational study of U.S. adults found the percentage reporting recent anxiety or depressive symptoms increased from 36% to 42% between…
Anxiety and depression symptoms rose among U.S. adults from Aug 2020 to Feb 2021, with biggest jumps in young adults and those with less edu…
Dance interventions improve quality of life and reduce depressive symptoms in breast cancer survivors
Dance programs may improve quality of life for women with breast cancer
A meta-analysis of 12 RCTs in women with breast cancer found dance interventions significantly improved quality of life (SMD=0.62) and reduc…
A review of 12 studies found that dance interventions significantly improved quality of life and reduced depressive symptoms for women with …