Research across Depression
Related studies from across the Depression family.
Depressive disorder in patients with diabetes increases all-cause mortality and metabolic complications
Depression Linked to Higher Mortality Risk in People with Diabetes
This meta-analysis of patients with diabetes and co-occurring depressive disorder found a 1.30 increased risk of all-cause mortality compare…
People with both diabetes and depression may face a higher risk of death and serious health complications compared to those with diabetes al…
Intranasal esketamine and intravenous ketamine provide the strongest evidence for treating depressive disorders
Ketamine and Esketamine Show Promise for Treatment-Resistant Depression
This narrative review evaluates various ketamine formulations for depressive disorders, finding the strongest evidence for intranasal esketa…
New evidence highlights how different forms of ketamine and esketamine may help patients struggling with treatment-resistant major depressiv…
Barriers to mental health care for Black populations include racism, stigma, and socioeconomic determinants
Barriers to mental health care for Black patients identified
This scoping review of 254 sources identifies prevalent mental health disorders and systemic barriers affecting the Black population. Key fi…
New research highlights how racism, stigma, and lack of access create significant hurdles for Black people seeking mental health care.
tDCS combined with cognitive-behavioral interventions shows no significant benefit over sham for depressive symptoms
tDCS Plus Talk Therapy Shows No Extra Depression Benefit
This meta-analysis of 321 patients with depressive disorders found no statistically significant difference in depressive symptoms, response …
Adding brain stimulation to talk therapy didn't beat sham for depression in a new analysis of 321 patients.
Platform-based food delivery work correlates with musculoskeletal disorders, fatigue, and mental health risks
Food Delivery Riders Face High Risks from Platform Management
This narrative review of 47 sources examines the occupational hazards faced by food delivery riders in China. The authors conclude that syst…
Delivery riders face significant physical and mental health risks, including musculoskeletal disorders and anxiety, due to intense work dema…
Mindfulness-based interventions improve emotion regulation and reduce anxiety in adolescents with emotional difficulties
Mindfulness training helps teens manage emotions and reduce anxiety
This meta-analysis of 11 randomized controlled trials found that mindfulness-based interventions significantly improved emotion regulation (…
Mindfulness programs can help teenagers struggling with intense emotions, showing consistent improvements in anxiety and depression symptoms…
Adding Chinese patent medicines to SSRIs improves HAMD scores and response rates in depressive disorder
Chinese Herbal Add-Ons May Boost Antidepressant Effects
This systematic review and network meta-analysis of 5,975 patients found that seven Chinese patent medicine (CPM) combinations with SSRIs si…
Adding certain Chinese patent medicines to standard antidepressants improved depression scores and response rates in a new analysis.
Dissociative symptoms correlate with greater severity and poorer outcomes in anxiety and depressive disorders
Dissociative Symptoms Linked to Severity in Anxiety and Depression
This scoping review of 300 studies examines the prevalence and clinical impact of dissociative symptoms in adults with anxiety and depressio…
High levels of dissociation are linked to more severe symptoms and poorer treatment outcomes for people with anxiety and depression.
Combined sleep and circadian interventions improve depressive symptoms and sleep quality in adults with mental disorders
Sleep and Circadian Interventions May Ease Depressive Symptoms
This systematic review and meta-analysis of randomized trials indicates that combined sleep and circadian interventions significantly reduce…
Targeting sleep and circadian rhythms may improve mood, sleep quality, and daily functioning for adults living with depression and other men…
Circadian rhythm disruption is a core pathophysiological mechanism for anxiety and depressive disorders
Circadian Disruption Linked to Anxiety and Depression
This systematic review examines the role of circadian rhythms in mental health. It identifies circadian disruption as a primary pathophysiol…
A new review suggests fixing your body clock could be key to treating anxiety and depression, not just a side effect.
Eicosapentaenoic acid evidence is most developed for depressive symptoms rather than brain aging
Fish oil may help manage symptoms of depression
This narrative review examines the role of eicosapentaenoic acid (EPA) in addressing depressive symptoms and brain aging. The authors conclu…
New research looks at how a specific type of fish oil, known as EPA, might support emotional well-being and brain health.
Functional and emotion-focused coping strategies are associated with lower distress in family carers
Coping styles impact mental health for parents of children with disabilities
This meta-analysis of 4548 participants examined the relationship between various coping strategies and psychological distress in family car…
Caregivers of dependent children face high stress, but research shows that specific ways of handling daily challenges can lower anxiety and …