Early-Onset Colorectal Cancer Shows Superior Survival vs Late-Onset in Retrospective Cohort
Younger Colon Cancer Patients Live Longer After Surgery
A retrospective cohort study of 4,596 colorectal cancer patients found that early-onset disease (EOCRC) was associated with significantly be…
Even with tougher tumors, younger colon cancer patients are living longer after surgery than older patients, and doctors now have hard data …
Global burden of early-onset colorectal cancer from alcohol, tobacco, and inactivity declined 1990-2021
More Young Adults Getting Colorectal Cancer — But One Risk Stands Out
This global cohort review analyzed early-onset colorectal cancer attributable to behavioral risk factors from 1990 to 2021. The overall burd…
While smoking and drinking risks drop, lack of physical activity is driving a sharp rise in colon cancer for adults under 50 worldwide.
Observational study suggests colibactin mutations are enriched in rectum regardless of polyp status
Why do some colon cancers start in the rectum while others do not?
This observational study analyzed whole-genome sequencing of colon crypts from 11 donors without polyps and 10 with polyps. The authors exam…
A toxin from E. coli bacteria causes specific DNA damage in the rectum, which may explain why some colon cancers start there, especially in …