Research across Septic Shock
Related studies from across the Septic Shock family.
Arterial hypotension is a late sign of decompensated shock linked to increased mortality and adverse neurologic outcomes in critically ill children
Low blood pressure in sick kids signals danger and needs careful management
This guideline narrative review addresses arterial hypotension, septic shock, and traumatic brain injury in critically ill infants and child…
Low blood pressure in critically ill children often means shock is worsening. Experts now suggest aiming for targets at least at the 10th pe…
Scoping review on androgen pathways and therapy in adult sepsis and septic shock
Sepsis Patients With Low Testosterone Face Higher Death Risks
This systematic scoping review synthesizes evidence on testosterone levels and androgen-based interventions in adult sepsis or septic shock.…
• Low testosterone strongly links to severe sepsis and death • Helps doctors spot high-risk ICU patients faster • Hormone therapy failed to …
Conservative oxygen targets show no mortality difference in mechanically ventilated critically ill adults
New Oxygen Rules Save Lives Without Extra Risk in ICU
This systematic review and meta-analysis of 20,447 mechanically ventilated critically ill adults in the ICU found no substantial difference …
ICU teams can safely use less oxygen for ventilated patients, new research shows, potentially reducing harm without raising death risk for m…
Narrative review of Shenfu Injection for sepsis-induced gastrointestinal injury and septic shock
A Chinese herbal therapy may protect the gut during septic shock
This narrative review examines Shenfu Injection for sepsis-induced acute gastrointestinal injury and septic shock.
A traditional Chinese herbal blend may help protect the gut during septic shock, offering a new angle on a deadly complication that often go…
Large language models show varying accuracy for data extraction in sepsis guidelines
AI models show promise for extracting sepsis study data
This study evaluated the performance of large language models, including ChatGPT-4o, Claude 3 Sonnet, and Gemini 1.5 Pro, for data extractio…
New tests show AI can help pull patient details from medical papers, but extracting clinical results remains a major challenge.
Non-invasive ultrasound defines snuffbox artery RI and PI reference ranges in healthy volunteers versus ICU patients with septic shock or hypertension
New blood flow numbers reveal hidden risks in shock patients
This prospective observational cohort study included 91 healthy volunteers and 55 ICU patients at a 4,900-bed tertiary care hospital in Chin…
A simple finger test now shows hidden blood flow problems that standard checks miss in sick patients.
Retrospective cohort study links pulse pressure levels to 28-day mortality in septic shock patients
New Blood Pressure Target Could Save Septic Shock Patients
This retrospective cohort study examined septic shock patients across two settings to assess pulse pressure levels during the first 24 h in …
A new study suggests a specific blood pressure range improves survival for people in septic shock.
Seraph Microbind filter used in a 7-year-old with refractory septic shock and invasive Streptococcus pyogenes infection
New Filter May Save Children in Life-Threatening Shock
This single case report describes a previously healthy 7-year-old girl with refractory septic shock and invasive Streptococcus pyogenes infe…
This device offers a new rescue option for kids whose bodies shut down from infection.
Thiamin supplementation associated with reduced mortality in septic shock patients
Thiamin Cuts Death Risk in Sepsis Shock
This meta-analysis of randomized controlled trials evaluated thiamin supplementation versus placebo or blank controls in patients with septi…
A common vitamin called thiamin lowers death risk and kidney failure needs for patients in septic shock, offering new hope for severe infect…
CytoSorb hemoadsorption shows no benefit and potential harm in small septic shock trial
A Promising Sepsis Treatment May Do More Harm Than Good
A single-center RCT of 31 adults with septic shock and high IL-6 found no significant difference in cumulative norepinephrine dose (primary …
A high-tech blood filter for sepsis failed to help patients and may have worsened early survival rates in a new study.
Socioeconomic factors associated with increased mortality in adults with sepsis or septic shock
Study finds poverty and lack of insurance linked to higher death rates from sepsis
A systematic review and meta-analysis of 13 observational studies involving 3,951,677 adults with sepsis or septic shock found that several …
Poverty and lack of private insurance are linked to higher death rates from sepsis, affecting nearly 4 million adults in a major review.
Neostigmine infusion in septic shock linked to lower TNF-alpha and 28-day mortality in single-center RCT
Neostigmine infusion linked to lower inflammation and mortality in septic shock trial
A single-center randomized controlled trial in adult ICU patients with septic shock compared a 5-day neostigmine infusion (0.2 mg/hr) to pla…
Septic shock patients receiving neostigmine showed lower inflammation, better organ scores, and fewer deaths compared to those on placebo in…