Research across Septic Shock
Related studies from across the Septic Shock family.
Elevated syndecan-1 levels correlate with severity and poor outcomes in patients with sepsis
Higher syndecan-1 levels linked to severe sepsis and poor outcomes
This meta-analysis of 4985 patients, including 3902 with sepsis, found significantly higher circulating syndecan-1 levels in sepsis patients…
A new analysis shows that higher levels of a specific protein can help doctors identify patients with the most severe forms of sepsis.
Low-dose corticosteroids reduce 90-day mortality in adults with severe community-acquired pneumonia
Low dose steroids may lower death rates in severe lung infections
This meta-analysis of 4,622 patients found that low-dose corticosteroids (≤400 mg hydrocortisone-equivalent daily) significantly reduced sho…
A review of clinical trials suggests that low-dose corticosteroids can reduce 90-day mortality for adults with severe lung infections like p…
IgM-enriched immunoglobulin shows directionally favorable but statistically inconclusive results for short-term mortality in sepsis
IgM Therapy for Sepsis Shows Promise but Not Proof
This meta-analysis of 411 adults with sepsis or septic shock found that IgM-enriched immunoglobulin (Pentaglobin) showed a favorable trend f…
A new analysis hints IgM therapy may lower sepsis deaths, but the evidence isn't strong enough to recommend it yet.
Skin perfusion parameters Mottling Score, CRT, and PPI correlate with higher mortality in sepsis patients
Skin Perfusion Markers Linked to Higher Sepsis Mortality Risk
This meta-analysis of 22 articles involving 2,727 subjects indicates that skin perfusion markers are associated with increased mortality ris…
Specific skin signs like mottling and slow capillary refill may help doctors identify patients with sepsis who are at a higher risk of death…
Arterial hypotension is a late sign of decompensated shock linked to increased mortality and adverse neurologic outcomes in critically ill children
Low blood pressure in sick kids signals danger and needs careful management
This guideline narrative review addresses arterial hypotension, septic shock, and traumatic brain injury in critically ill infants and child…
Low blood pressure in critically ill children often means shock is worsening. Experts now suggest aiming for targets at least at the 10th pe…
Scoping review on androgen pathways and therapy in adult sepsis and septic shock
Sepsis Patients With Low Testosterone Face Higher Death Risks
This systematic scoping review synthesizes evidence on testosterone levels and androgen-based interventions in adult sepsis or septic shock.…
• Low testosterone strongly links to severe sepsis and death • Helps doctors spot high-risk ICU patients faster • Hormone therapy failed to …
Conservative oxygen targets show no mortality difference in mechanically ventilated critically ill adults
New Oxygen Rules Save Lives Without Extra Risk in ICU
This systematic review and meta-analysis of 20,447 mechanically ventilated critically ill adults in the ICU found no substantial difference …
ICU teams can safely use less oxygen for ventilated patients, new research shows, potentially reducing harm without raising death risk for m…
Narrative review of Shenfu Injection for sepsis-induced gastrointestinal injury and septic shock
A Chinese herbal therapy may protect the gut during septic shock
This narrative review examines Shenfu Injection for sepsis-induced acute gastrointestinal injury and septic shock.
A traditional Chinese herbal blend may help protect the gut during septic shock, offering a new angle on a deadly complication that often go…
Large language models show varying accuracy for data extraction in sepsis guidelines
AI models show promise for extracting sepsis study data
This study evaluated the performance of large language models, including ChatGPT-4o, Claude 3 Sonnet, and Gemini 1.5 Pro, for data extractio…
New tests show AI can help pull patient details from medical papers, but extracting clinical results remains a major challenge.
Non-invasive ultrasound defines snuffbox artery RI and PI reference ranges in healthy volunteers versus ICU patients with septic shock or hypertension
New blood flow numbers reveal hidden risks in shock patients
This prospective observational cohort study included 91 healthy volunteers and 55 ICU patients at a 4,900-bed tertiary care hospital in Chin…
A simple finger test now shows hidden blood flow problems that standard checks miss in sick patients.
Retrospective cohort study links pulse pressure levels to 28-day mortality in septic shock patients
New Blood Pressure Target Could Save Septic Shock Patients
This retrospective cohort study examined septic shock patients across two settings to assess pulse pressure levels during the first 24 h in …
A new study suggests a specific blood pressure range improves survival for people in septic shock.
Seraph Microbind filter used in a 7-year-old with refractory septic shock and invasive Streptococcus pyogenes infection
New Filter May Save Children in Life-Threatening Shock
This single case report describes a previously healthy 7-year-old girl with refractory septic shock and invasive Streptococcus pyogenes infe…
This device offers a new rescue option for kids whose bodies shut down from infection.