Research across Epilepsy
Related studies from across the Epilepsy family.
Transcutaneous auricular vagus nerve stimulation shows potential for depression, epilepsy, migraine, and post-stroke rehabilitation
Vagus Nerve Stimulation Shows Potential for Depression and Migraine
This narrative review of 72 articles explores the mechanism and therapeutic potential of transcutaneous auricular vagus nerve stimulation (t…
A new method of nerve stimulation may offer potential benefits for managing conditions like migraine, epilepsy, and depression.
Newer-generation antiseizure medications improve treatment retention and safety in older adults with epilepsy
Newer Antiseizure Medications May Improve Treatment Retention in Seniors
This meta-analysis of 2,507 patients found no significant difference in seizure freedom between newer and older antiseizure medications. How…
Newer antiseizure medications may help older adults stay on their treatment more consistently than older medications for managing epilepsy.
Low-frequency rTMS and cathodal tDCS provide consistent seizure reductions in drug-resistant epilepsy
Non-invasive Neuromodulation Shows Promise for Drug-Resistant Epilepsy
This narrative review explores non-invasive neuromodulation for drug-resistant epilepsy, highlighting low-frequency rTMS and cathodal tDCS a…
Newer non-invasive brain stimulation methods like rTMS and tDCS show consistent results in reducing seizure frequency for patients with drug…
Sleep disturbances and obstructive sleep apnea lower seizure thresholds and impact sleep architecture in epilepsy
Sleep patterns and conditions impact seizure control in epilepsy
This narrative review explores the bidirectional relationship between epilepsy and sleep disorders. It highlights how NREM sleep promotes se…
New insights show how specific sleep stages and conditions like sleep apnea can influence seizure activity and quality of life for people wi…
Psychological and behavioral interventions significantly reduce depression severity in people with epilepsy
Behavioral Therapies May Help Reduce Depression in People with Epilepsy
This meta-analysis evaluates the efficacy of psychological and behavioral interventions for depression in patients with epilepsy. The analys…
Psychological and behavioral therapies, such as cognitive behavioral therapy, show promise in reducing depression symptoms for people living…
LLM-based risk-of-bias assessments show limited agreement with human reviewers in neurology prognosis studies
AI Tools Show Potential for Assessing Medical Research Quality
This systematic review evaluates an LLM-based pipeline using zero-shot prompting for Risk-of-Bias (ROB) assessment using the QUIPS framework…
New research explores how AI models can help experts quickly assess the quality and bias of medical studies on conditions like stroke and ep…
253 autism-associated genes identified via rare coding variation in 62,429 individuals
253 genes linked to autism may also affect other conditions
This meta-analysis of exome sequencing data from over 1.5 million individuals identified 253 autism-associated genes and 497 genes impacting…
A massive genetic study found 253 autism-linked genes, many tied to other brain and body conditions, opening new paths for understanding.
Exercise may stabilize neuroprotective biomarkers and improve immunometabolic profiles in patients with epilepsy
Exercise May Help Protect Brain Health in People with Epilepsy
This narrative review explores the impact of exercise on fluid biomarkers including S100β, GFAP, and NfL in epilepsy. The authors suggest th…
New research suggests that regular exercise may help stabilize brain proteins and protect nerve cells in people living with epilepsy.
Depressive symptoms affect 40% and anxiety 36% of adults with epilepsy
Depression and anxiety common in epilepsy
This meta-analysis of cross-sectional studies found that depressive symptoms occur in 40% and anxiety symptoms in 36% of adults with epileps…
About 40% of adults with epilepsy screen positive for depression and 36% for anxiety, a new meta-analysis finds.
Ketogenic diets reduce seizures in 69% of refractory epilepsy patients in Latin America
Ketogenic Diets Show Promise for Reducing Seizures in Epilepsy
This meta-analysis of 13 studies involving 566 patients with refractory epilepsy in Latin America found that ketogenic dietary therapies wer…
A review of data from over 500 patients shows that ketogenic dietary therapies can reduce seizures and help some achieve seizure freedom.
Ketogenic diet therapy yields 42.82% seizure reduction in drug-resistant epilepsy
Ketogenic Diet Therapy Shows Promise for Drug Resistant Epilepsy
This meta-analysis of 1019 adolescents and adults with drug-resistant epilepsy found that ketogenic diet therapy was associated with a 42.82…
A ketogenic diet may help reduce seizures by over 50 percent in many adults and adolescents with drug resistant epilepsy.
Educational programs significantly improve knowledge and management of epilepsy in children and their caregivers
Epilepsy education improves parents' lives, not seizures
This meta-analysis of 10 randomized controlled trials found that educational programs significantly improved knowledge (SMD = 1.29) and dise…
Educational programs for kids with epilepsy and their parents boost knowledge and quality of life, but don't clearly cut seizures.