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Extensive coronary artery disease

Part of Coronary Artery Disease

1 published article · Updated continuously

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.

Research across Coronary Artery Disease

Related studies from across the Coronary Artery Disease family.

Ticagrelor and prasugrel show no statistically credible difference in 1-year MACE for ACS patients
Cardiology Meta-analysis
Ticagrelor and prasugrel show no statistically credible difference in 1-year MACE for ACS patients Comparing Ticagrelor and Prasugrel for Patients with Heart Conditions After Surgery
This meta-analysis of retrospective new-user cohort studies analyzed 133,718 adults with acute coronary syndrome undergoing first PCI. The s…
A large study compared two heart medications to see which was safer and more effective for patients after a heart procedure.
Multimodal framework using Lp(a), hs-CRP, and colchicine addresses residual risk in Chinese CAD patients
Rheumatology Guideline
Multimodal framework using Lp(a), hs-CRP, and colchicine addresses residual risk in Chinese CAD patients New Framework Suggests Colchicine Use for Coronary Artery Disease
This perspective piece proposes a multimodal framework for assessing residual risk in Chinese patients with coronary artery disease. It sugg…
A new framework suggests using specific markers like hs-CRP and Lp(a) to help identify patients who may benefit from low-dose colchicine.
Angiography-derived FFR meets noninferiority for revascularization rate in stable coronary artery disease
Cardiology RCT
Angiography-derived FFR meets noninferiority for revascularization rate in stable coronary artery disease New imaging method shows promise for heart artery procedures
This randomized trial of 401 patients with stable coronary artery disease found that angiography-derived FFR was noninferior to pressure wir…
A new wire-free imaging technique may offer a practical way to guide heart surgery decisions for patients with coronary artery disease.
Side branch drug-coated balloons may preserve lumen volume in coronary bifurcation lesions
Cardiology RCT
Side branch drug-coated balloons may preserve lumen volume in coronary bifurcation lesions Drug Coated Balloons May Help Preserve Side Branch Openings
This randomized trial substudy of 221 patients with coronary artery disease evaluated adjunctive side branch drug-coated balloons (SB-DCB) v…
A new trial suggests that drug coated balloons may help maintain the size of small side branches in patients with coronary artery disease.
EPA and DHA supplementation significantly lowers inflammatory markers in coronary artery disease patients
Cardiology RCT
EPA and DHA supplementation significantly lowers inflammatory markers in coronary artery disease patients Fish oil supplements may lower inflammation in heart disease patients
This secondary analysis of a randomized trial involved 240 patients with stable coronary artery disease on statin therapy. Supplementation w…
A study shows that taking specific fish oils can lower certain markers of inflammation in people with coronary artery disease.
CPAP does not modify exercise-derived autonomic or chronotropic responses in nonsleepy patients with CAD and OSA
Cardiology RCT
CPAP does not modify exercise-derived autonomic or chronotropic responses in nonsleepy patients with CAD and OSA CPAP use does not change heart rate recovery for some patients
This randomized controlled trial of 204 patients with coronary artery disease and obstructive sleep apnea found that CPAP did not alter hear…
A study of people with heart disease and sleep apnea found that CPAP machines did not improve specific heart rate recovery markers during ex…
Comprehensive care significantly reduces all-cause death from 8.2% to 4.7% in coronary artery disease
Cardiology RCT
Comprehensive care significantly reduces all-cause death from 8.2% to 4.7% in coronary artery disease Comprehensive heart care reduces death and major cardiac events
This randomized controlled trial of 1028 participants with high risk factors for coronary artery disease found that comprehensive care reduc…
A new approach combining lifestyle changes with medical treatment significantly lowers the risk of death and heart attacks for those with co…
Oral anticoagulant monotherapy significantly reduces major bleeding compared to combined therapy in stable coronary artery disease
Cardiology Meta-analysis
Oral anticoagulant monotherapy significantly reduces major bleeding compared to combined therapy in stable coronary artery disease Anticoagulant alone may cut bleeding risk in heart patients
This meta-analysis of randomized controlled trials involving 5924 patients found that oral anticoagulant monotherapy results in a comparable…
For some heart patients, skipping aspirin and using only an anticoagulant may lower bleeding risk without raising heart risks.
FFRangio is noninferior to pressure-wire measurements for intermediate coronary stenosis at 1 year
Cardiology RCT
FFRangio is noninferior to pressure-wire measurements for intermediate coronary stenosis at 1 year Trial shows imaging technology matches wire measurements for heart disease
This randomized controlled trial of 1930 patients undergoing coronary angiography found that FFRangio was noninferior to pressure-wire based…
A new imaging tool may offer a safer way to measure blood flow in the heart during procedures for coronary artery disease.
Novel pharmacotherapies like resmetirom and GLP-1 receptor agonists offer potential concurrent hepatic and cardiovascular benefits
Cardiology Sys. Review
Novel pharmacotherapies like resmetirom and GLP-1 receptor agonists offer potential concurrent hepatic and cardiovascular benefits New Medications Show Potential to Treat Liver and Heart Disease
This systematic review examines the epidemiological links and shared pathophysiological mechanisms between metabolic dysfunction-associated …
Newer drugs like resmetirom and GLP-1 receptor agonists may offer dual benefits for patients with both liver and heart conditions.
Staged PCI reduces severe kidney injury risk after TAVR in aortic stenosis and CAD
Cardiology Meta-analysis
Staged PCI reduces severe kidney injury risk after TAVR in aortic stenosis and CAD Staged heart procedures may lower risk of severe kidney injury
This meta-analysis of 7,119 patients with aortic stenosis and coronary artery disease undergoing TAVR found that staged PCI did not signific…
A new look at heart surgery data suggests that spacing out certain procedures could protect kidneys from severe damage.
SK-121 digital health program improves disease knowledge and medication adherence after PCI
Cardiology RCT
SK-121 digital health program improves disease knowledge and medication adherence after PCI Digital health program improves knowledge and blood pressure for heart patients
This single-centre RCT of 200 patients found that the SK-121 multimodal digital health program did not significantly reduce the SMART2 risk …
A digital health program helped heart patients improve their medical knowledge, medication habits, and blood pressure after a procedure.