Comprehensive geriatric assessment modifies treatment plans and associates with survival in older adults with gastrointestinal malignancies
Does a pre-surgery check-up actually change treatment plans and help older adults with cancer live longer?
This retrospective cohort study evaluated 273 adults aged ≥65 years referred for preoperative comprehensive geriatric assessment (CGA) at a …
A pre-surgery health check changed treatment plans for 21% of older cancer patients and was linked to better survival.
Systematic review examines HIF-1α role in digestive system inflammation and cancer
Could a single protein be fueling both gut inflammation and cancer?
A systematic review synthesizing existing literature found HIF-1α contributes to pathogenesis of inflammatory digestive diseases and promote…
A single protein called HIF-1α may be driving both gut inflammation and digestive cancers while helping tumors resist drugs and evade the im…
Phase 1b/2 study of ERAS-007 combinations in advanced GI malignancies completes enrollment of 101 patients
Can a new drug combination help people with advanced colorectal or pancreatic cancer?
A Phase 1b/2 platform study evaluated ERAS-007 in combination with other cancer therapies in patients with advanced gastrointestinal maligna…
A new drug combination tested in advanced colorectal and pancreatic cancer aims to find safe doses and early signs of tumor shrinkage in pat…
Research across Cancer
Related studies from across the Cancer family.
Meta-analysis identifies germline susceptibility loci for rare cancers including MDS and GIST
Genes linked to rare cancers found in large study of over 480,000 people
This meta-analysis of observational cohorts from over 480,000 individuals identified novel germline susceptibility loci for rare cancers.
A huge study of over 480,000 people found new genes that raise the risk of several rare cancers, offering clues for families and doctors.
H2H nutrition management improves PG-SGA scores in malnourished GI cancer patients on chemotherapy
Can better nutrition management help cancer patients fight fatigue and stay stronger during chemo?
A 100-patient RCT in gastric/colorectal cancer patients with malnutrition risk (PG-SGA ≥2) found that whole-cycle nutrition management based…
A new nutrition plan for stomach and colon cancer patients during chemo improved strength, reduced fatigue, and boosted quality of life comp…
Questions about Gastrointestinal Malignancies
Can a comprehensive geriatric assessment help older adults with gastrointestinal malignancies live longer?
Comprehensive geriatric assessment helps older adults with gastrointestinal cancers live longer by identifying frailty and changing treatment plans to avoid complications.
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