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Generalized pustular psoriasis

Part of Psoriasis

1 published article · Updated continuously

Clinical Trial Landscape

Clinical Trials for Generalized pustular psoriasis

7 trials tracked for Generalized pustular psoriasis: 4 in phase 3 or 4 and 2 with published results. The most-cited published study has 32 citations.

7Trials tracked
4Phase 3 & 4
0Recruiting
2With published results
Phase distribution
Phase 4 1 Phase 3 3 Phase 2 3
  1. Phase 4 A Study of Ixekizumab (LY2439821) in Participants in Japan With Generalized Pustular Psoriasis and Erythrodermic Psoriasis Completed · 32 cited
  2. Phase 3 Study to Evaluate the Efficacy and Safety of Imsidolimab (ANB019) in the Treatment of Subjects With GPP Completed
  3. Phase 3 An Expanded Access Trial in Japan to Provide Spesolimab to People With a Flare-up in Generalized Pustular Psoriasis Who Have no Other Treatment Options Completed
  4. Phase 3 An Expanded Access Program in China to Provide Spesolimab to People With a Flare-up in Generalized Pustular Psoriasis Who Have no Other Treatment Options Completed
  5. Phase 2 Effisayil™ 1: A Study to Test Spesolimab (BI 655130) in Patients With a Flare-up of a Skin Disease Called Generalized Pustular Psoriasis Completed
  6. Phase 2 A Study to Evaluate the Efficacy and Safety of Imsidolimab (ANB019) in Adults With Generalized Pustular Psoriasis Completed
Show 1 more trials
  1. Phase 2 A Study to Test Whether BI 655130 (Spesolimab) Prevents Flare-ups in Patients With Generalized Pustular Psoriasis Completed

Showing the 7 most-cited and recently-updated of 7 trials. Browse the full registry →

Trial data sourced from ClinicalTrials.gov. Counts describe the research landscape and are not a treatment recommendation. Informational only — not medical advice.

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.

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Staphylococcal infections may mimic paradoxical psoriasis in patients receiving TNF-alpha inhibitors for systemic conditions
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Smoking and alcohol linked to higher psoriasis risk in large meta-analysis Smoking raises psoriasis risk significantly while alcohol shows a smaller effect
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Icotrokinra 200 mg daily achieves PASI 75 in 73% of patients at Week 16 versus 11% with placebo in moderate-to-severe plaque psoriasis
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This systematic review and meta-analysis evaluates icotrokinra for moderate-to-severe plaque psoriasis in 1951 patients. The pooled analysis…
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Switching between adalimumab and biosimilar adalimumab-atto shows similar pharmacokinetics in plaque psoriasis
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Switching between adalimumab and biosimilar adalimumab-atto shows similar pharmacokinetics in plaque psoriasis Switching between adalimumab and its biosimilar is safe and similar
This phase 3 RCT in 425 adults with moderate-to-severe plaque psoriasis found that multiple switches between adalimumab RP and biosimilar ad…
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Narrative review offers theoretical basis for selecting biologic therapies in psoriasis patients with renal concerns
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Narrative review offers theoretical basis for selecting biologic therapies in psoriasis patients with renal concerns New Psoriasis Treatments May Protect Kidneys While Fighting Skin Flares
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Targeted therapies for psoriasis and psoriatic arthritis significantly alter lipid profiles across diverse patient populations
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Narrative review discusses ginsenosides for skin conditions including psoriasis and dermatitis with noted evidence gaps
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A review of ginsenosides for skin issues like psoriasis and melanoma found the evidence is insufficient and absorption is low.
Herring roe oil reduces inflammatory biomarkers in mild-to-moderate psoriasis
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In a randomized controlled trial post hoc analysis of 64 patients with mild-to-moderate psoriasis, oral herring roe oil supplementation for …
A small trial found that herring roe oil reduced several blood-based inflammation markers in people with mild-to-moderate psoriasis over 26 …
Secukinumab improves skin response in Chinese patients with psoriatic arthritis
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Secukinumab improves skin response in Chinese patients with psoriatic arthritis Secukinumab linked to skin improvement in Chinese psoriatic arthritis patients
This observational cohort study of 446 Chinese patients with psoriatic arthritis found that treatment with secukinumab for over 12 weeks was…
In Chinese psoriatic arthritis patients, secukinumab treatment was associated with significant skin improvement and better quality of life o…