Research across Epilepsy
Related studies from across the Epilepsy family.
253 autism-associated genes identified via rare coding variation in 62,429 individuals
253 genes linked to autism may also affect other conditions
This meta-analysis of exome sequencing data from over 1.5 million individuals identified 253 autism-associated genes and 497 genes impacting…
A massive genetic study found 253 autism-linked genes, many tied to other brain and body conditions, opening new paths for understanding.
Exercise may stabilize neuroprotective biomarkers and improve immunometabolic profiles in patients with epilepsy
Exercise May Help Protect Brain Health in People with Epilepsy
This narrative review explores the impact of exercise on fluid biomarkers including S100β, GFAP, and NfL in epilepsy. The authors suggest th…
New research suggests that regular exercise may help stabilize brain proteins and protect nerve cells in people living with epilepsy.
Depressive symptoms affect 40% and anxiety 36% of adults with epilepsy
Depression and anxiety common in epilepsy
This meta-analysis of cross-sectional studies found that depressive symptoms occur in 40% and anxiety symptoms in 36% of adults with epileps…
About 40% of adults with epilepsy screen positive for depression and 36% for anxiety, a new meta-analysis finds.
Ketogenic diets reduce seizures in 69% of refractory epilepsy patients in Latin America
Ketogenic Diets Show Promise for Reducing Seizures in Epilepsy
This meta-analysis of 13 studies involving 566 patients with refractory epilepsy in Latin America found that ketogenic dietary therapies wer…
A review of data from over 500 patients shows that ketogenic dietary therapies can reduce seizures and help some achieve seizure freedom.
Ketogenic diet therapy yields 42.82% seizure reduction in drug-resistant epilepsy
Ketogenic Diet Therapy Shows Promise for Drug Resistant Epilepsy
This meta-analysis of 1019 adolescents and adults with drug-resistant epilepsy found that ketogenic diet therapy was associated with a 42.82…
A ketogenic diet may help reduce seizures by over 50 percent in many adults and adolescents with drug resistant epilepsy.
Educational programs significantly improve knowledge and management of epilepsy in children and their caregivers
Epilepsy education improves parents' lives, not seizures
This meta-analysis of 10 randomized controlled trials found that educational programs significantly improved knowledge (SMD = 1.29) and dise…
Educational programs for kids with epilepsy and their parents boost knowledge and quality of life, but don't clearly cut seizures.
Gray matter volume reductions occur in multiple extrahippocampal regions across temporal lobe epilepsy subtypes
Brain Imaging Reveals Distinct Patterns in Temporal Lobe Epilepsy
This meta-analysis and observational study identifies specific gray matter volume (GMV) alterations in patients with temporal lobe epilepsy.…
New research identifies specific patterns of brain tissue changes in different types of temporal lobe epilepsy, helping map how the conditio…
28% recurrence rate after antiseizure medication withdrawal in children with epilepsy
Stopping seizure meds in children: 28% recurrence risk
This meta-analysis of 3,226 children with epilepsy found a pooled recurrence rate of 28% (95% CI: 23%–33%) after antiseizure medication with…
About 28% of children with epilepsy who stop antiseizure medications will have a seizure return. Several factors can increase this risk.
MRgLITT provides comparable QALYs to open resection for children with drug-resistant focal epilepsy
Laser surgery shows better survival for children with drug-resistant epilepsy
This systematic review utilizes a Markov decision analytic model to compare MRgLITT and open resective surgery against medical management in…
A new analysis suggests laser surgery can offer a 4.6 year survival advantage over medical management for children with certain types of epi…
Exercise training promotes adult hippocampal neurogenesis by influencing the neurochemical environment and cell cycle dynamics
Exercise training may help grow new neurons in the brain
This narrative review synthesizes evidence regarding exercise training and its effects on adult hippocampal neurogenesis in conditions such …
Physical exercise can trigger the growth of new neurons and stem cells, potentially offering new paths for treating brain disorders like Alz…
Longer epilepsy duration correlates with significantly lower DTI-ALPS index scores across multiple epilepsy subtypes
Longer Epilepsy Duration Linked to Lower Glymphatic Function
This meta-analysis of 449 patients found a significant negative association between epilepsy duration and the DTI-ALPS index, suggesting imp…
Research suggests that the length of time a person lives with epilepsy may be linked to changes in how the brain clears waste.
Ketogenic diet therapies improve seizure reduction rates in children and adults with drug-resistant epilepsy
Ketogenic diet shows promise for people with drug-resistant epilepsy
This systematic review and meta-analysis evaluates ketogenic diet therapies for drug-resistant epilepsy across children, adolescents, and ad…
A ketogenic diet can significantly reduce seizure frequency for children, teens, and adults living with drug-resistant epilepsy.