Research across Liver disease
Related studies from across the Liver disease family.
Macrophage-to-myofibroblast transition drives fibrosis across kidney, heart, lung, liver, and retina
Macrophages May Turn Into Scar-Forming Cells In Organs
This systematic review synthesizes evidence that macrophages can directly differentiate into extracellular matrix-producing myofibroblasts v…
A review finds certain immune cells may transform into scar-forming cells in the kidney, heart, lung, liver, and retina.
Exosomal miRNAs Show High Diagnostic Accuracy for Hepatocellular Carcinoma
Exosomal microRNAs show promise for detecting liver cancer
This meta-analysis evaluated exosomal microRNAs as non-invasive biomarkers for hepatocellular carcinoma across 1442 HCC patients, 761 health…
New data shows that specific tiny molecules in the blood could help doctors identify liver cancer more accurately in patients with liver dis…
Bangga extracts show antibacterial, anti-inflammatory, antiviral, and antitumor activity in preclinical synthesis
Extracts of Aconitum tanguticum Show Potential for Several Conditions
This systematic review synthesizes preclinical evidence on Aconitum tanguticum (Bangga), reporting antibacterial, anti-inflammatory, antivir…
Research into Aconitum tanguticum extracts shows potential antibacterial, antiviral, and anti-inflammatory properties for various inflammato…
Lidocaine-esketamine infusion reduces movement-evoked pain and opioid consumption in hepatic resection patients
New drug combination reduces pain after liver surgery
This randomized controlled trial of 304 patients undergoing elective hepatic resections found that a lidocaine-esketamine infusion significa…
A new mix of lidocaine and esketamine may lower pain and opioid use for patients recovering from liver surgery during the first three days.
MDS patients have 6.2 times higher cardiovascular disease prevalence than the general population
People with myelodysplastic syndrome face higher risk of heart disease
This meta-analysis of 71,400 patients with myelodysplastic syndrome (MDS) found a significantly higher prevalence of comorbidities compared …
Patients with myelodysplastic syndrome face much higher rates of heart failure and other chronic illnesses compared to the general populatio…
Statin therapy reduces hepatocellular carcinoma risk and hepatic decompensation by 46% in chronic liver disease
Statin Therapy Linked to Lower Risks in Chronic Liver Disease
This umbrella review of systematic reviews analyzed data from 10,515,877 participants to evaluate statin effects on chronic liver disease. T…
A large-scale review suggests statin use may lower the risk of liver cancer and serious complications for people with chronic liver disease.
Insulin resistance and hyperinsulinemia drive bidirectional links between biological aging and age-related chronic diseases
Insulin Resistance Links Aging and Chronic Diseases
This narrative review explores the reciprocal relationship between insulin resistance, hyperinsulinemia, and mechanisms of biological aging.…
This review explores how insulin resistance and high insulin levels connect aging to diseases like diabetes, heart disease, and kidney disea…
Splenic stiffness measurement shows high sensitivity for varices in children with non-cirrhotic portal hypertension
Measuring Splenic Stiffness Helps Identify Dangerous Vein Enlargement in Children
This systematic review and diagnostic test accuracy meta-analysis of 1027 children found that splenic stiffness measurement (SSM) has high s…
New research shows that measuring spleen stiffness can help doctors find dangerous vein growth in children with liver issues.
Functional sweet tea components may mitigate metabolic risks including hyperglycemia and liver disease
Sweet Tea Components Show Potential to Manage Metabolic Health Issues
This systematic review identifies 22 functional sweet tea plants and 27 components that potentially impact glycolipid metabolism, anti-infla…
Natural sweet tea plants may offer ways to manage blood sugar, cholesterol, and blood pressure through various internal health pathways.
Precision nutrition offers dynamic optimization for managing patients with chronic liver disease through individualized metabolic profiles
Precision nutrition offers a new way to manage liver disease
This narrative review explores the role of precision nutrition in managing chronic liver disease. The authors argue that tailoring nutrition…
Tailoring nutrition to an individual's unique metabolism could change how doctors manage chronic liver disease and improve patient care.
Periodontitis and chronic liver disease linked through proposed oral-gut-liver axis
Conceptual framework links liver, gut, immune, and oral health
This narrative review proposes a Liver-Gut-Immune-Oral Axis linking periodontitis and chronic liver disease. The authors synthesize mechanis…
A narrative review suggests a conceptual link between liver disease and oral health, though this biological system needs direct experimental…
Combining Pentraxin-3 and AFP increases sensitivity to 0.92 for hepatocellular carcinoma diagnosis in chronic liver disease
New blood test helps doctors find liver cancer earlier with better accuracy than old methods alone
This systematic review and meta-analysis evaluated diagnostic markers in adults with chronic liver disease suspected of hepatocellular carci…
A review of 1,179 patients shows a new marker called PTX3 works well for finding liver cancer. Using both PTX3 and AFP together finds more c…