Research across Liver disease
Related studies from across the Liver disease family.
Insulin resistance and hyperinsulinemia drive bidirectional links between biological aging and age-related chronic diseases
Insulin Resistance Links Aging and Chronic Diseases
This narrative review explores the reciprocal relationship between insulin resistance, hyperinsulinemia, and mechanisms of biological aging.…
This review explores how insulin resistance and high insulin levels connect aging to diseases like diabetes, heart disease, and kidney disea…
Splenic stiffness measurement shows high sensitivity for varices in children with non-cirrhotic portal hypertension
Measuring Splenic Stiffness Helps Identify Dangerous Vein Enlargement in Children
This systematic review and diagnostic test accuracy meta-analysis of 1027 children found that splenic stiffness measurement (SSM) has high s…
New research shows that measuring spleen stiffness can help doctors find dangerous vein growth in children with liver issues.
Functional sweet tea components may mitigate metabolic risks including hyperglycemia and liver disease
Sweet Tea Components Show Potential to Manage Metabolic Health Issues
This systematic review identifies 22 functional sweet tea plants and 27 components that potentially impact glycolipid metabolism, anti-infla…
Natural sweet tea plants may offer ways to manage blood sugar, cholesterol, and blood pressure through various internal health pathways.
Precision nutrition offers dynamic optimization for managing patients with chronic liver disease through individualized metabolic profiles
Precision nutrition offers a new way to manage liver disease
This narrative review explores the role of precision nutrition in managing chronic liver disease. The authors argue that tailoring nutrition…
Tailoring nutrition to an individual's unique metabolism could change how doctors manage chronic liver disease and improve patient care.
Periodontitis and chronic liver disease linked through proposed oral-gut-liver axis
Conceptual framework links liver, gut, immune, and oral health
This narrative review proposes a Liver-Gut-Immune-Oral Axis linking periodontitis and chronic liver disease. The authors synthesize mechanis…
A narrative review suggests a conceptual link between liver disease and oral health, though this biological system needs direct experimental…
Combining Pentraxin-3 and AFP increases sensitivity to 0.92 for hepatocellular carcinoma diagnosis in chronic liver disease
New blood test helps doctors find liver cancer earlier with better accuracy than old methods alone
This systematic review and meta-analysis evaluated diagnostic markers in adults with chronic liver disease suspected of hepatocellular carci…
A review of 1,179 patients shows a new marker called PTX3 works well for finding liver cancer. Using both PTX3 and AFP together finds more c…
Narrative review on PCSK9 inhibitors for familial hypercholesterolemia
Review explores PCSK9 inhibitors for familial hypercholesterolemia
This narrative review synthesizes evidence on PCSK9 inhibitors, including evolocumab, for familial hypercholesterolemia. The authors discuss…
This review looks at PCSK9 inhibitors like evolocumab for people with familial hypercholesterolemia. It discusses how these drugs work and t…
Narrative review explores gut microbiota role in postoperative delirium in liver disease
Gut bacteria may help prevent delirium after surgery
This narrative review examines the potential link between gut microbiota alterations and postoperative delirium in older surgical patients w…
A review suggests that gut health could play a role in preventing postoperative delirium in older patients.
Ursodeoxycholic acid reduces ALT and fibrosis in chronic liver disease patients
UDCA Improves Liver Enzymes and Fibrosis in Chronic Liver Disease
This phase IV RCT in 262 patients with chronic liver disease and elevated ALT found that ursodeoxycholic acid 100 mg three times daily for 8…
A phase IV trial found that ursodeoxycholic acid (UDCA) significantly reduced ALT levels and improved fibrosis scores in patients with chron…
Review of antiviral and immunotherapeutic strategies for chronic hepatitis B
New antiviral strategies show promise for chronic hepatitis B infection
This narrative review synthesizes evidence on antiviral and immunotherapeutic strategies for chronic hepatitis B. The authors highlight func…
A review of new treatments suggests combination therapies may offer future value for managing chronic hepatitis B, cirrhosis, and liver canc…
Narrative review explores macrophage reprogramming for liver fibrosis and MASH
Scientists explore new ways to reprogram liver cells to heal damaged tissue and stop scarring
This narrative review summarizes macrophage reprogramming strategies for liver fibrosis and MASH. Approaches include gene modulation, pharma…
A recent review looks at fresh methods to change how liver immune cells behave. These changes could help heal liver scarring and improve hea…
Narrative review explores aryl hydrocarbon receptor's dual role in liver injury and protection
Liver's Secret Switch Flips Between Harm and Healing
This narrative review examines the aryl hydrocarbon receptor (AhR) in liver disease. AhR activation drives liver damage through mitochondria…
Your liver has a hidden sensor that pollution can flip to destroy mode but scientists just found how to lock it in repair mode