SHOX gene deficiency causes Langer mesomelic dysplasia with severe disproportionate short stature and limb hypoplasia
SHOX Gene Deficiency Linked to Specific Skeletal Growth Disorders
This narrative review explores the molecular basis of Langer mesomelic dysplasia caused by SHOX gene deficiency. The authors synthesize find…
A review of the SHOX gene shows how its deficiency leads to specific limb shortening and short stature in certain conditions.
Multi-factor management models for thoracic aortic disease improve precision beyond diameter-only assessment
New multi-factor model improves care for thoracic aortic disease
This mini-review synthesizes the management of thoracic aortic disease in young patients with various genetic and structural conditions. The…
Doctors are moving beyond just measuring artery size to look at genetics and lifestyle when managing heart risks in young patients.
Narrative review suggests transcatheter PDA closure improves safety and reduces radiation compared to fluoroscopy
A new way to close a heart hole uses less radiation and takes less time
This narrative review evaluates transcatheter closure of patent ductus arteriosus in patients with this condition. The authors synthesize ev…
A review suggests using a catheter to close a patent ductus arteriosus is safer, uses less radiation, and takes less time than older methods…
Review of bedside ligation for patent ductus arteriosus in an extremely low birth weight infant
A single case shows bedside ligation works for a tiny newborn with a heart hole
This review and synthesis examines a single case report of bedside ligation for patent ductus arteriosus in an extremely low birth weight in…
A single case report suggests bedside ligation can close a heart hole and help a tiny newborn breathe easier without major surgery.
CPET reference values established for asymptomatic repaired Tetralogy of Fallot patients
Kids with repaired heart defects get better test results—here’s why it matters
This observational cohort study established sex- and age-specific CPET reference values in 290 asymptomatic patients with repaired Tetralogy…
This could change how doctors measure heart strength in young patients born with serious heart defects.
Narrative review discusses systemic-to-pulmonary shunts for complex congenital heart defects in pediatric populations
Heart Surgery Technique Still Saves Babies After 80 Years
This narrative review examines the continued relevance of systemic-to-pulmonary shunts, including Blalock-Taussig-Thomas variants, for compl…
For babies with life-threatening heart defects, a decades-old surgical technique remains a reliable lifeline that newer methods can't yet fu…
Percutaneous closure using the poly-L-lactic acid (PLLA) device in pediatric patients with atrial septal defect
New Device Closes Heart Holes in Kids
This prospective, single-center, first-in-human trial evaluated percutaneous closure using the poly-L-lactic acid (PLLA) device in 36 pediat…
A new milk-protein heart device closed holes in kids for five years, letting their bodies heal naturally without permanent metal implants.
Paracetamol or ibuprofen treatment outcomes in preterm infants with patent ductus arteriosus: a retrospective cohort analysis
Tiny Hearts, Big Risk: New Clues to a Common Preemie Problem
This retrospective cohort study evaluated pharmacological treatment with intravenous paracetamol or ibuprofen in 60 preterm infants with pat…
For the tiniest premature babies, an open heart passage that doesn't close can be life-threatening, but early treatment helps most infants r…
Immediate postpartum cardiac surgery in neonates with critical congenital heart disease shows feasible outcomes
For newborns with critical heart defects, immediate surgery showed a 95% survival rate
This retrospective case series of 21 neonates with critical congenital heart disease at a Beijing hospital assessed immediate postpartum car…
Newborns with critical heart defects had a 95% survival rate when surgery began within eight minutes of birth at Beijing Anzhen Hospital.
Synchronous PCG-ECG monitoring may supplement echocardiography for pediatric VSD subtype diagnosis
A Stethoscope Upgrade May Spot Holes in Kids' Hearts Faster
A prospective cohort study of 59 children with suspected ventricular septal defect (VSD) found that synchronous phonocardiogram-electrocardi…
A wearable device that records a child's heartbeat and heart sounds together may flag subtle differences between two kinds of heart holes.
In pediatric complex CHD, VR modeling showed superior utility over CT alone for coronary assessment and strong inter-operator agreement
Why Surgeons Are Strapping On VR Headsets Before Kids' Heart Procedures
This retrospective bi-center feasibility study evaluated patient-specific 3D reconstruction and virtual reality (VR) modeling versus CT alon…
Virtual reality lets pediatric cardiologists walk inside a child's heart before surgery, helping them spot dangers that flat scans can miss.
Early growth hormone initiation in Turner syndrome linked to higher final height in retrospective study
Starting Growth Hormone Earlier Could Add Inches to Adult Height
A retrospective cohort study of 31 Turner syndrome patients followed from 1996 to 2021 found that initiating growth hormone therapy at ≤6 ye…
A 25-year study confirms that starting treatment early is key for height, but it also reveals a dangerous drop-off in medical care as girls …
All Heart Defects, Congenital Articles
- SHOX gene deficiency causes Langer mesomelic dysplasia with severe disproportionate short stature and limb hypoplasia
- Multi-factor management models for thoracic aortic disease improve precision beyond diameter-only assessment
- Narrative review suggests transcatheter PDA closure improves safety and reduces radiation compared to fluoroscopy
- Review of bedside ligation for patent ductus arteriosus in an extremely low birth weight infant
- CPET reference values established for asymptomatic repaired Tetralogy of Fallot patients
- Narrative review discusses systemic-to-pulmonary shunts for complex congenital heart defects in pediatric populations
- Percutaneous closure using the poly-L-lactic acid (PLLA) device in pediatric patients with atrial septal defect
- Paracetamol or ibuprofen treatment outcomes in preterm infants with patent ductus arteriosus: a retrospective cohort analysis
- Immediate postpartum cardiac surgery in neonates with critical congenital heart disease shows feasible outcomes
- Synchronous PCG-ECG monitoring may supplement echocardiography for pediatric VSD subtype diagnosis
- In pediatric complex CHD, VR modeling showed superior utility over CT alone for coronary assessment and strong inter-operator agreement
- Early growth hormone initiation in Turner syndrome linked to higher final height in retrospective study
- Early prone positioning associations with gas-exchange indices in children after TOF repair
- 3D CT and angiography show variable accuracy for PDA stent sizing depending on ductal tortuosity