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Patent Ductus Arteriosus

Part of Heart Defects, Congenital

4 published articles · Updated continuously

Clinical Trial Landscape

Clinical Trials for Patent Ductus Arteriosus

4 trials tracked for Patent Ductus Arteriosus.

4Trials tracked
0Phase 3 & 4
0Recruiting
0With published results
Phase distribution
Phase 2 1 Other / NA 3
  1. Phase 2 Early Treatment Versus Delayed Conservative Treatment of the Patent Ductus Arteriosus Completed
  2. N/A AMPLATZER Duct Occluder II Additional Sizes Completed
  3. N/A Pocket Echocardiography System (PES) for Detection of PDA in Neonates Completed
  4. N/A AMPLATZER Duct Occluder II Clinical Study Completed

Showing the 4 most-cited and recently-updated of 4 trials. Browse the full registry →

Trial data sourced from ClinicalTrials.gov. Counts describe the research landscape and are not a treatment recommendation. Informational only — not medical advice.

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.

Questions about Patent Ductus Arteriosus

What are the outcomes of using paracetamol versus ibuprofen for PDA in preemies?

Paracetamol and ibuprofen are similarly effective for closing PDA in preterm infants, with paracetamol possibly causing fewer side effects like gastrointestinal bleeding or kidney issues.

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Does transcatheter PDA closure improve safety compared to traditional fluoroscopy methods?

Yes, transcatheter PDA closure with echocardiographic guidance or preprocedural CT improves safety and reduces radiation compared to traditional fluoroscopy methods.

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Can ibuprofen or paracetamol effectively treat PDA in preterm infants?

Yes, both ibuprofen and paracetamol (acetaminophen) can effectively close a hemodynamically significant PDA in preterm infants, but recent trials show no benefit over expectant management for early treatment.

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Is bedside ligation a safe option for an extremely low birth weight infant with PDA?

Bedside ligation is considered a safe and optimized option for extremely low birth weight infants with PDA, often allowing them to be weaned from ventilation quickly.

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