Cardiac myosin inhibitors improve exercise capacity and health status in patients with hypertrophic cardiomyopathy
New heart medication shows promise for hypertrophic cardiomyopathy patients
This meta-analysis evaluated the impact of cardiac myosin inhibitors on adults with symptomatic non-obstructive hypertrophic cardiomyopathy.…
A new class of heart drugs may improve exercise capacity and quality of life for people with a specific heart muscle condition.
AI-empowered echocardiography shows promise for HCM diagnosis and risk prediction, but validation is lacking
AI Echocardiography Shows Promise for Heart Condition
This systematic review synthesizes AI-empowered echocardiography applications in hypertrophic cardiomyopathy, categorizing methods by comple…
AI-powered echocardiography may improve diagnosis and risk prediction for hypertrophic cardiomyopathy, but large-scale validation is still n…
Exercise improves cardiorespiratory fitness and quality of life in patients with hypertrophic cardiomyopathy
Exercise improves heart health and fitness for HCM patients
This meta-analysis of 9,702 patients with hypertrophic cardiomyopathy (HCM) found that exercise is associated with increased peak oxygen con…
New research shows that structured exercise can improve heart fitness, body weight, and quality of life for people with hypertrophic cardiom…
Global Longitudinal Strain as a Potential Predictor of Sudden Cardiac Death in Hypertrophic Cardiomyopathy
Heart imaging helps identify high risk in cardiomyopathy patients
Meta-analysis suggests reduced global longitudinal strain identifies high-risk patients with hypertrophic cardiomyopathy prone to fatal arrh…
A new way to measure heart muscle movement may help doctors identify which patients with a specific heart condition are at higher risk for s…
Systematic review and meta-analysis of MYH7 versus MYBPC3 variants in obstructive hypertrophic cardiomyopathy
Specific heart genes predict different risks for HCM patients
This systematic review and meta-analysis pooled data from 192,361 participants in cohort or registry studies to compare MYH7 and MYBPC3 vari…
New data shows specific heart genes predict different risks for people with obstructive hypertrophic cardiomyopathy and guide care plans.
Review of Visual Standardized Quantification for LGE in Cardiomyopathy
A new tool improves accuracy and speed for spotting heart risks in patients with cardiomyopathy
This narrative review synthesizes evidence on Visual Standardized Quantification of LGE (VISTAQ) versus conventional techniques.
A new imaging method showed better accuracy and faster analysis times for predicting heart events in patients with specific heart diseases.
Review synthesizes genetic insights and CMR imaging traits as potential therapeutic targets for cardiomyopathies
New Clues to Treating Heart Muscle Diseases Found in Your Genes
This Mendelian randomization and imaging mediation analysis review identifies potential therapeutic targets for hypertrophic and dilated car…
This study connects your genes to specific heart changes, opening the door to more personalized treatments for heart muscle disease.
Deep learning model improves LVOT obstruction classification in hypertrophic cardiomyopathy patients
AI Reads Heart Videos Without Special Tools
This US cohort study evaluated a multi-view deep learning model for classifying left ventricular outflow tract obstruction in hypertrophic c…
A new AI reads routine heart videos to spot dangerous blockages in thickened hearts, potentially making care faster and cheaper without need…
Echocardiographic and biochemical markers predict mortality in children with hypertrophic cardiomyopathy
Heart Scans May Predict Danger in Kids With Thickened Heart Muscle
This retrospective cohort study evaluated 41 children diagnosed with hypertrophic cardiomyopathy at The First Affiliated Hospital of Guangxi…
New research shows that simple heart measurements from a routine scan can help predict which children with a thickened heart muscle face a h…
GWAS meta-analysis identifies 89 loci for mitral valve prolapse and genetic links to hypertrophic cardiomyopathy
New DNA Clues Link Heart Valve to Dangerous Rhythms
This meta-analysis of genome-wide association studies (GWAS) evaluated genetic factors in over 2.2 million individuals, including 21,517 cas…
Imagine your heart has a tiny door that sometimes swings too wide.
Plasma proteins linked to HCM severity identified in MYBPC3 carriers and UK Biobank
Could blood proteins predict dangerous heart conditions like sudden cardiac arrest in people with specific gene mutations?
This observational study examined 144 MYBPC3 pathogenic variant carriers and 6,492 UK Biobank participants to identify plasma proteins assoc…
Blood proteins linked to heart failure and sudden cardiac arrest appear in people with specific gene mutations, offering new warning signs f…
Cardiac genetic testing mainstreaming increases uptake and reduces wait times but lowers informed decision making
Cardiac genetic testing in clinics increased access but reduced informed decision making
An observational study of patients with hypertrophic or dilated cardiomyopathy compared genetic testing offered in cardiology clinics (mains…
Offering genetic testing in cardiology clinics boosted access and cut wait times, yet only 62% of patients felt fully informed compared to 9…
Research across Cardiomyopathy
Related studies from across the Cardiomyopathy family.
Transthyretin stabilizers and RNA-silencing therapies attenuate cardiac remodeling in transthyretin amyloid cardiomyopathy
New Therapies May Slow Heart Damage in Amyloid Cardiomyopathy
This meta-analysis of 3646 adults with cardiac amyloidosis found that transthyretin stabilizers and RNA-silencing therapies are associated w…
Specific drug therapies may help stabilize heart structure and slow the progression of damage for adults with transthyretin amyloid cardiomy…
Gene, inflammation, and metabolic dysregulation drive pathophysiology in pediatric dilated cardiomyopathy
Gene, Inflammation, Metabolism Link in Child Heart Failure
This systematic review examines the role of the gene-inflammation-metabolism axis in pediatric dilated cardiomyopathy. The authors identify …
A new review links genes, inflammation, and metabolism in pediatric dilated cardiomyopathy, offering a roadmap for targeted treatments.
Supraventricular tachyarrhythmias occur more frequently in patients with Arrhythmogenic Cardiomyopathy and Brugada Syndrome
Heart conditions like Brugada syndrome increase risk of rapid heartbeats
This systematic review of 30 studies indicates that supraventricular tachyarrhythmias (SVT) are more frequent in patients with Arrhythmogeni…
Patients with certain heart conditions face a higher risk of fast heartbeats, which can lead to complications like heart failure or unnecess…
Vascular smooth muscle cell immune interactions drive remodeling across cardiovascular diseases
How blood vessel cells drive heart disease and high blood pressure
This narrative review synthesizes mechanisms of VSMC-immune interactions in atherosclerosis, hypertension, aortic aneurysms, and arteritis. …
A new review reveals how blood vessel cells change in heart disease, high blood pressure, and more.
Review of Diabetic Cardiomyopathy without reported trial data or specific outcomes
Review of Diabetic Cardiomyopathy offers new understanding of this heart condition
This narrative review addresses Diabetic cardiomyopathy but reports no specific population, sample size, or intervention details. The author…
This review looks at diabetic cardiomyopathy to help doctors understand this specific heart problem better for patients with diabetes.
Mini review examines sudden cardiac death risks in marathon runners across different age groups
Marathon running links to higher heart risk in older men and full-distance participants
This mini review synthesizes evidence on sudden cardiac death (SCD) and coronary artery disease in marathon runners. The authors note that r…
A review of marathon runners shows heart risks vary by age, sex, and race distance, with most events happening near the finish.
Narrative review discusses Ganoderma lucidum polysaccharides for diabetes and related complications
New research shows mushroom compounds may help control blood sugar and fix organ damage
This narrative review examines the theoretical potential of Ganoderma lucidum polysaccharides (GLPs) for diabetes and associated conditions.
A common mushroom extract could help lower blood sugar and heal organ damage for millions of people with diabetes
Deep learning model screens for transthyretin amyloid cardiomyopathy using ECG images
AI spots hidden heart disease from routine ECGs
This observational study developed a deep learning model to identify transthyretin amyloid cardiomyopathy from ECG images.
A new AI tool finds signs of a dangerous heart disease in routine ECGs years before symptoms worsen, offering hope for earlier treatment in …
Acoramidis associated with lower diuretic intensification in transthyretin amyloid cardiomyopathy
New Heart Drug Shows Lower Risk of Hospitalization vs Older Option
In this retrospective cohort study using US claims data, acoramidis was associated with a lower risk of diuretic intensification and a compo…
A new heart drug cut diuretic needs and hospitalizations more than the older option in early real-world use.
PSI-QPI metrics improved prediction of TTN-TV disease penetrance and expressivity in cardiomyopathy patients
New Tool Predicts Heart Failure Risk in Genetic Heart Disease
This cohort study evaluated PSI-DCM-LR-15, QPI, and PSI-QPI metrics in patients with cardiomyopathy due to TTN-TV and cardiac tissue from or…
A new combination of tests can more accurately predict which patients with genetic heart muscle disease will develop serious heart failure.
Thyroid dysfunction and atrial fibrillation risk in hypertrophic obstructive cardiomyopathy patients
Thyroid Levels May Predict Heart Rhythm Problems in a Common Heart Condition
This observational cohort study of 755 HOCM patients examined the association between thyroid dysfunction and atrial fibrillation risk.
Monitoring thyroid function could become a simple way to help identify and manage heart rhythm risks in patients with a specific heart muscl…
Geranylgeranylacetone mitigates desmin variant-induced atrial cardiomyopathy mechanisms in vitro
A Hidden Heart Flaw May Explain Some Early Atrial Fibrillation
This preclinical in vitro study evaluated HL-1 atrial cardiomyocytes expressing human desmin wild-type or pathogenic variants (p.S13F, p.N34…
A broken heart protein called desmin can silently damage the upper chambers and spark lifelong rhythm problems, while a potential rescue dru…
Questions about Hypertrophic Cardiomyopathy
Which echocardiographic and biochemical markers can predict mortality risk for children with hypertrophic cardiomyopathy?
In children with hypertrophic cardiomyopathy, echocardiographic markers like left atrial size and left ventricular wall thickness, and biochemical markers such as NT-proBNP, predict mortality risk.
Full answer →Can visual standardized quantification of LGE help doctors see heart scarring better in hypertrophic cardiomyopathy?
Yes, VISTAQ, a visual standardized method, helps doctors see and quantify heart scarring (LGE) in HCM with excellent reproducibility, without needing complex software.
Full answer →All Hypertrophic Cardiomyopathy Articles
- Cardiac myosin inhibitors improve exercise capacity and health status in patients with hypertrophic cardiomyopathy
- AI-empowered echocardiography shows promise for HCM diagnosis and risk prediction, but validation is lacking
- Exercise improves cardiorespiratory fitness and quality of life in patients with hypertrophic cardiomyopathy
- Global Longitudinal Strain as a Potential Predictor of Sudden Cardiac Death in Hypertrophic Cardiomyopathy
- Systematic review and meta-analysis of MYH7 versus MYBPC3 variants in obstructive hypertrophic cardiomyopathy
- Review of Visual Standardized Quantification for LGE in Cardiomyopathy
- Review synthesizes genetic insights and CMR imaging traits as potential therapeutic targets for cardiomyopathies
- Echocardiographic and biochemical markers predict mortality in children with hypertrophic cardiomyopathy
- Deep learning model improves LVOT obstruction classification in hypertrophic cardiomyopathy patients
- GWAS meta-analysis identifies 89 loci for mitral valve prolapse and genetic links to hypertrophic cardiomyopathy
- Plasma proteins linked to HCM severity identified in MYBPC3 carriers and UK Biobank
- Cardiac genetic testing mainstreaming increases uptake and reduces wait times but lowers informed decision making
- Multimodality cardiac imaging aids differentiation between hypertrophic cardiomyopathy and cardiac amyloidosis