Research across Stroke
Related studies from across the Stroke family.
Evaluating Thrombectomy Efficacy and Safety in Patients with Medium or Distal Arterial Occlusions
Trial shows thrombectomy results for specific types of ischemic stroke
A randomized trial of 244 patients with MDVO found no significant difference in outcomes between thrombectomy and medical management alone.
A clinical trial found that adding thrombectomy to medical treatment did not improve outcomes for certain stroke patients and increased blee…
Efficacy of Intravenous Thrombolysis for Acute Ischemic Stroke Patients Late in Window
Thrombolytic drugs improve recovery for patients with late ischemic stroke
Meta-analysis confirms that IV thrombolysis improves functional outcomes in patients presenting 4.5 to 24 hours after stroke onset without i…
Patients with a stroke between 4.5 and 24 hours after symptoms can see better recovery with certain clot-busting medications.
No-reflow phenomenon affects at least 25% of patients after reperfusion in acute ischemic stroke
Small blood vessel blockages hinder recovery after a major stroke
This narrative review examines the no-refure phenomenon in acute ischemic stroke, noting it affects at least 25% of patients after reperfusi…
Even after doctors open a large blocked artery, tiny blood vessel issues can stop blood from reaching damaged brain tissue in at least 25% o…
Tenecteplase shows higher mRS 0 to 1 rates in distal M3 and beyond occlusions
Trial shows tenecteplase may help specific types of stroke
This secondary analysis of a randomized clinical trial involved 492 patients with perfusion imaging-confirmed stroke within 4.5 hours of sym…
A secondary analysis suggests tenecteplase may lead to better outcomes for patients with specific types of stroke compared to alteplase.
Intravenous tirofiban before endovascular treatment increases risk of parenchymal hematoma type 2
Trial shows tirofiban increases bleeding risk in some stroke patients
This randomized controlled trial of 945 patients with acute large vessel occlusion of the anterior circulation found that intravenous tirofi…
A large trial found that using tirofiban before certain stroke treatments may increase the risk of specific types of brain bleeding.
Clopidogrel plus aspirin for 21 days provides favorable net clinical benefit in minor ischemic stroke
Dual antiplatelet therapy shows mixed results for stroke prevention
This Bayesian network meta-analysis of 8 trials involving 50,349 adults with minor ischemic stroke or high-risk TIA found that clopidogrel p…
New data compares different blood thinner combinations to find the best way to prevent a second stroke after a minor medical emergency.
Dual antiplatelet therapy reduces major ischemic events in week 1 of minor stroke or TIA
Dual antiplatelet therapy reduces stroke risk in first week
This meta-analysis of 27,167 patients with minor ischemic stroke or high-risk TIA found that DAPT significantly reduced major ischemic event…
A new analysis shows dual antiplatelet therapy significantly lowers stroke risk in the first week, but carries a higher risk of bleeding.
High Lp-PLA2 levels triple recurrent stroke risk in ischemic stroke patients
High Lp-PLA2 levels linked to higher risk of stroke recurrence
This meta-analysis of 2527 patients with ischemic stroke found that high Lp-PLA2 levels were associated with a nearly 3-fold increased risk …
A specific protein in the blood, called Lp-PLA2, may help doctors identify which stroke patients are at higher risk for another medical emer…
Early oral anticoagulants show no significant difference in stroke risk compared to late initiation
Early blood thinners show no extra risks for stroke patients
This meta-analysis of 6522 adults with atrial fibrillation and recent ischemic stroke found no significant difference in recurrent ischemic …
Starting blood thinners soon after a stroke does not increase the risk of bleeding or death compared to waiting.
BCI-based training yields statistically robust but clinically modest improvements in post-stroke lower-limb motor function
Brain-Computer Interface Training Improves Lower-Limb Function After Stroke
This meta-analysis of randomized controlled trials evaluates BCI-based training for patients with lower-limb motor dysfunction after stroke.…
New research shows that brain-computer interface training can help patients with lower-limb motor issues improve their movement after a stro…
Traditional Chinese Exercises improve sleep quality and reduce anxiety and depression in post-stroke survivors
Traditional Chinese Exercises Improve Sleep After Stroke
This meta-analysis of 690 post-stroke survivors found that Traditional Chinese Exercises (TCEs) significantly improved sleep quality (MD -2.…
Tai Chi and similar exercises may help stroke survivors sleep better and ease anxiety and depression, a new analysis finds.
Exercise-based cardiac rehabilitation improves aerobic capacity and systolic blood pressure in stroke and TIA patients
Exercise programs improve heart health after stroke or TIA
This rapid review and meta-analysis of 490 patients indicates that exercise-based cardiac rehabilitation improves aerobic capacity by 28 m a…
Exercise-based cardiac rehabilitation helps people who have had a stroke or TIA improve their aerobic capacity and lower their blood pressur…