Systematic review and meta-analysis on neuroimaging biomarkers for futile recanalization in stroke thrombectomy
New imaging clues reveal which stroke patients may not recover after surgery
This systematic review and meta-analysis synthesized observational data on neuroimaging biomarkers for predicting futile recanalization in a…
New imaging signs on brain scans may help predict which stroke patients will not recover well even after a successful procedure to remove th…
Meta-analysis models cost-effectiveness of IV alteplase plus thrombectomy for large vessel occlusion stroke
Adding alteplase to stroke surgery is cost-effective when treatment starts within 170 minutes
This meta-analysis models cost-effectiveness using individual patient data from 6 trials involving 2,268 patients across 16 countries.
Adding clot-busting medicine to stroke surgery saves money and improves value when treatment starts within 170 minutes, but benefits fade af…
Non-randomized trial of Zoom system for LVO stroke reperfusion exceeds performance goals
Can a new stroke device clear deadly clots faster and more often?
This is a prospective, multicenter, non-randomized investigational device exemption trial in 260 adults with anterior circulation LVO stroke…
A new stroke device cleared deadly clots in 83% of patients within three tries, restoring blood flow in just 19 minutes.
Earlier endovascular therapy within 24 hours associated with smaller infarct and better outcomes in LVO stroke
Does waiting longer for stroke treatment cause more brain damage and worse recovery?
This prospective cohort study evaluated 216 patients with anterior circulation large-vessel occlusion stroke treated with endovascular thera…
Waiting longer for stroke treatment causes more dead brain tissue and leaves fewer patients able to live independently after 90 days.
Direct Transfer to Angiography Suite Shows No Benefit, Higher Hemorrhage Risk in Severe Stroke
Does rushing stroke patients straight to treatment improve their recovery?
A randomized trial in 115 adults with acute severe stroke from large vessel occlusion compared direct transfer to angiography suite (DTAS) w…
Skipping the CT scan to rush stroke patients straight to treatment did not improve recovery and increased the risk of serious brain bleeding…
Research across Stroke
Related studies from across the Stroke family.
Tenecteplase and alteplase improve functional outcomes in extended windows but increase symptomatic intracranial hemorrhage risk
Tenecteplase Shows Potential Benefits for Late Acute Ischemic Stroke
This meta-analysis of 4,944 patients evaluated intravenous thrombolysis with alteplase or tenecteplase between 4.5 and 24 hours after stroke…
Tenecteplase may offer similar benefits to alteplase for stroke patients while potentially carrying a lower risk of brain bleeding.
Obstructive sleep apnea is associated with a 2- to 3-fold increase in stroke risk
Sleep disorders significantly impact recovery for stroke patients
This narrative review examines the prevalence and impact of sleep disorders, including obstructive sleep apnea (OSA), in stroke patients. Th…
Up to 84% of stroke patients suffer from sleep disorders, which can hinder recovery and increase the risk of future strokes.
Adjunctive acupoint application increases clinical response rates in post-stroke sleep disorders
Chinese herbal acupoint application may improve sleep after a stroke
This meta-analysis of 608 patients found that adjunctive acupoint application significantly increased trial-defined clinical response rates …
New data suggests that adding herbal acupoint treatments to care can improve sleep quality for people living with sleep disorders after a st…
Detectable Microembolic Signals on TCD Linked to 2.85-Fold Higher Odds of Poor Stroke Outcome
Microembolic signals predict poor outcomes for stroke patients
This meta-analysis of 1,777 patients with acute ischemic stroke found that detectable microembolic signals on transcranial Doppler were asso…
Detecting specific microembolic signals during a stroke can help doctors identify patients at a higher risk for poor physical recovery.
Non-invasive brain stimulation shows favorable tolerability and 94.9% completion rate for post-stroke upper limb rehabilitation
Brain Stimulation Shows Good Safety for Post-Stroke Arm Recovery
This systematic review and network meta-analysis of 2,640 participants evaluated non-invasive brain stimulation (NIBS) for post-stroke upper…
Brain stimulation techniques show high completion rates and favorable safety for patients recovering arm movement after a stroke.
Acupuncture-based interventions improve Fugl-Meyer Assessment scores for post-stroke foot drop compared to conventional treatment
Acupuncture may improve movement for patients with post-stroke foot drop
This meta-analysis of 4,596 patients found that acupuncture-based interventions, including traditional and electroacupuncture, improved Fugl…
Acupuncture combined with standard care may help stroke survivors regain movement and improve scores in foot drop recovery.
Transcranial direct current stimulation combined with cognitive training yields largest improvements in post-stroke cognitive function
Brain stimulation and training help stroke survivors regain memory
This systematic review of 3,842 patients with post-stroke cognitive impairment found that transcranial direct current stimulation combined w…
New research shows that combining brain stimulation with cognitive training helps stroke survivors improve their memory and thinking skills.
Robotics-based interventions show stronger evidence for improving upper-limb motor function after stroke
Robotics Show Strong Potential for Stroke Recovery of Arm Function
This systematic review and network meta-analysis of 1,145 stroke survivors evaluated virtual reality, robotics, and brain-computer interface…
New research suggests that robotics-based therapies may offer significant improvements for stroke survivors regaining movement in their arms…
BCI-based interventions improve FMA-UE scores in patients with stroke and poststroke hemiplegia
Brain-computer interfaces show promise for stroke recovery and mobility
This network meta-analysis of 2906 patients with stroke and poststroke hemiplegia found that BCI-based interventions significantly improved …
New data shows that brain-computer interfaces can help stroke survivors regain arm movement and perform daily tasks more effectively.
Bright light therapy improves subjective sleep quality in adults with stroke
Bright Light Therapy May Improve Sleep Quality After Stroke
This systematic review and meta-analysis of 343 adults with stroke found that bright light therapy (BLT) significantly improves subjective s…
Bright light therapy may help improve how patients feel about their sleep quality after a stroke, though results on sleep continuity are les…
Wearable digital biomarkers show potential for neurorehabilitation monitoring, but evidence is heterogeneous and early
Wearable devices track movement and health for neurological recovery
This scoping review of 56 studies synthesizes evidence on wearable-derived digital biomarkers in neurological rehabilitation, focusing on st…
Wearable sensors can track movement and physical signs to help people recovering from stroke, Parkinson disease, and spinal cord injuries.
Paired vagus nerve stimulation with task-specific rehabilitation improves durable upper-limb outcomes in chronic ischemic stroke
Vagus Nerve Stimulation Shows Promise for Stroke Recovery
This mini review examines the impact of paired vagus nerve stimulation (pVNS) combined with task-specific rehabilitation for patients with c…
New research suggests that paired vagus nerve stimulation combined with rehabilitation may improve arm movement for people with chronic stro…
Questions about Large Vessel Occlusion Stroke
What are the risks of higher hemorrhage with direct transfer for my stroke?
Direct transfer to the angiography suite may increase the risk of symptomatic intracranial hemorrhage in severe stroke patients, based on a 2024 randomized trial.
Full answer →Is combining IV alteplase with thrombectomy cost-effective for large vessel occlusion stroke?
Combining IV alteplase with thrombectomy is cost-effective when given early, but the benefit drops as the time from stroke onset to the drug increases.
Full answer →Can neuroimaging biomarkers predict if my stroke treatment will fail?
Neuroimaging biomarkers like lower ASPECTS scores can predict a higher risk of poor recovery even after successful clot removal, but timing of treatment also affects final brain damage.
Full answer →