Shorter rifamycin-containing regimens show comparable efficacy to longer isoniazid monotherapy for latent tuberculosis infection
Shorter drug plans may help children finish tuberculosis treatments
This meta-analysis evaluated shorter rifamycin-containing regimens against a nine-month isoniazid course in children with latent tuberculosi…
New data suggests shorter treatment plans for latent tuberculosis can help children complete their medication without increasing the risk of…
Report describes tuberculosis-related practices among US health care providers
Report examines tuberculosis-related practices among U.S. health care providers
A non-research report describes tuberculosis-related practices among health care providers in the United States.
A new report describes tuberculosis-related practices among health care providers in the United States.
Research across Tuberculosis
Related studies from across the Tuberculosis family.
Multidrug-resistant tuberculosis prevalence is 5.2% among patients with bacteriologically confirmed cases in Cameroon
Identifying key risks for drug resistant tuberculosis infections in Cameroon
This meta-analysis of 28 studies involving 9,931 patients identifies a 5.2% pooled prevalence of multidrug-resistant tuberculosis (MDR-TB) i…
New data shows that past infections and lifestyle factors like alcohol use can increase the risk of developing hard-to-treat tuberculosis.
Respiratory viral coinfections reshape immune signaling and granuloma stability in Mycobacterium tuberculosis infections
Viral Infections May Change How the Body Fights Tuberculosis
This narrative review synthesizes how respiratory viruses, including SARS-CoV-2 and influenza, impact host immune signaling and granuloma eq…
Research shows that common respiratory viruses like flu or COVID-19 can change how the immune system responds to tuberculosis infections.
6-month bedaquiline, linezolid, delamanid, and levofloxacin or clofazimine regimen is noninferior to 9-month standard care
Trial shows shorter treatment works for resistant tuberculosis
This Phase 3 randomized controlled noninferiority trial evaluated a 6-month treatment strategy for pulmonary rifampicin-resistant tuberculos…
A new six-month treatment plan for drug-resistant tuberculosis showed similar success rates to the standard nine-month course.
Video observed therapy improves treatment success and adherence in adults with tuberculosis
Digital Tools Show Better Success Rates for Tuberculosis Treatment
This network meta-analysis of 29 randomized controlled trials evaluated digital health interventions for tuberculosis. Video observed therap…
Video observed therapy shows higher success and adherence rates for patients with tuberculosis compared to traditional face-to-face methods.
Water buffalo act as reservoirs for infectious diseases in mixed livestock systems
Water Buffalo May Spread Diseases to Other Livestock
This systematic review analyzes 180 articles regarding infectious diseases in water buffalo. The authors conclude that these animals are inc…
A review of 180 articles suggests water buffalo act as disease reservoirs, meaning they can pass infections to other animals in mixed farmin…
HIV linked to lower odds of post-TB lung disease; undernutrition raises risk
Undernutrition and HIV may lower or raise lung damage risk after tuberculosis in low-income nations
This systematic review and meta-analysis of 41 studies in LMICs found that HIV was associated with reduced odds of spirometry-defined post-t…
New analysis of data from low-income countries shows mixed results on how HIV, diabetes, and poor nutrition affect lung health after tubercu…
Immediate antituberculosis therapy did not reduce mortality in HIV-related sepsis overall
Immediate TB treatment helps only those with confirmed infection in HIV sepsis
This trial investigated whether starting antituberculosis treatment immediately or using high doses improved survival in adults with HIV-rel…
In HIV sepsis, starting TB drugs immediately did not lower death rates overall, but helped only patients later confirmed to have TB.
Ethambutol optic neuropathy incidence 1.54 percent with renal impairment and hypertension as key risk factors
Kidney disease and high blood pressure raise risk of vision loss from TB drug
This systematic review and meta-analysis synthesized evidence on ethambutol optic neuropathy and tuberculous meningitis complications. The p…
A massive review of over 260,000 patients found that kidney problems and high blood pressure make vision loss from the TB drug ethambutol mu…
Narrative review on vitamin D and VDR in gastrointestinal and pulmonary diseases
Vitamin D's Role in Gut and Lung Health Examined
This narrative review synthesizes evidence on vitamin D deficiency and VDR expression across gastrointestinal and pulmonary conditions. The …
A review explores how vitamin D deficiency and VDR expression may influence digestive and respiratory diseases, but more research is needed.
Case report review: BPaLM for MDR-TB with cerebral or bone involvement shows mixed outcomes
New Drug Regimen Shows Promise For Rare Bone And Brain TB Cases
This review of a case report describes two patients with multidrug-resistant tuberculosis (MDR-TB) involving cerebral or bone sites treated …
A new short drug combo cleared bone and brain TB in one patient but side effects stopped treatment for another.
Systematic review and meta-analysis of MDR-TB prevalence in the MENA region
TB drug resistance in Middle East and North Africa
This meta-analysis of 25 studies from 6 countries synthesized the prevalence of multidrug-resistant tuberculosis in the MENA region. The poo…
A review of 25 studies found about 3.5% of TB patients in the region have drug-resistant strains. The findings highlight a need for stronger…
Meta-analysis of dolutegravir-based ART and risk-stratified HIV care in Uganda
HIV Treatment Works Better Now, But One Problem Remains
This meta-analysis and cohort review examined viral non-suppression rates among people with HIV in Uganda receiving dolutegravir-based ART. …
New HIV drugs are highly effective, yet thousands of patients in Uganda still have uncontrolled virus, and a fresh approach using routine da…