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Home › Conditions › Ventricular Dysfunction

Ventricular Dysfunction

Subtypes of Ventricular Dysfunction

Left ventricular dysfunction 3 Left ventricular diastolic dysfunction 2 Left Ventricular Systolic Dysfunction 1 Right ventricular dysfunction 0

6 published articles · Updated continuously

Clinical Trial Landscape

Clinical Trials for Ventricular Dysfunction

11 trials tracked for Ventricular Dysfunction: 1 in phase 3 or 4.

11Trials tracked
1Phase 3 & 4
0Recruiting
0With published results
Phase distribution
Phase 3 1 Phase 2 2 Other / NA 8
  1. Phase 3 RED-HF™ Trial - Reduction of Events With Darbepoetin Alfa in Heart Failure Trial Completed
  2. Phase 2 The Effect of Intramyocardial Injection of Mesenchymal Precursor Cells on Myocardial Function in Patients Undergoing LVAD Implantation Completed
  3. Phase 2 Safety & Efficacy of Intramyocardial Injection of Mesenchymal Precursor Cells on Myocardial Function in LVAD Recipients Completed
  4. N/A ConsultaTM CRT-D Clinical Evaluation Study Completed
  5. N/A Thoratec HeartMate II Left Ventricular Assist System (LVAS) for Bridge to Cardiac Transplantation Completed
  6. N/A Thoratec HeartMate II Left Ventricular Assist System (LVAS) for Destination Therapy Completed
Show 5 more trials
  1. N/A Biopace Study: Biventricular Pacing for Atrioventricular Block to Prevent Cardiac Desynchronization Completed
  2. N/A Focused Cardiac Ultrasound Completed
  3. N/A HeartMate 3 ELEVATE™ Registry Completed
  4. N/A Safety and Clinical Performance of the Protecta ICD and CRT-D Completed
  5. N/A Vest Prevention of Early Sudden Death Trial and VEST Registry Completed

Showing the 11 most-cited and recently-updated of 11 trials. Browse the full registry →

Trial data sourced from ClinicalTrials.gov. Counts describe the research landscape and are not a treatment recommendation. Informational only — not medical advice.

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.
Off-pump CABG reduces mortality risk and stroke risk in patients with left ventricular dysfunction
Cardiology Meta-analysis
Off-pump CABG reduces mortality risk and stroke risk in patients with left ventricular dysfunction Off-pump heart surgery shows lower death risk for weak hearts
This meta-analysis of 35,863 patients with multivessel coronary artery disease and left ventricular dysfunction (ejection fraction ≤40%) fou…
A large review of over 35,000 patients suggests off-pump heart surgery may reduce mortality and stroke risks for those with weakened heart m…
Jul 1, 2026
Elective unloading with a microaxial flow pump showed no material difference in outcomes versus standard care in severe left ventricular dysfunction
Cardiology RCT
Elective unloading with a microaxial flow pump showed no material difference in outcomes versus standard care in severe left ventricular dysfunction Heart Pump Strategy Backfires for Weakened Hearts During High-Risk Surgery
This randomized controlled trial enrolled 300 patients with severe left ventricular dysfunction and extensive coronary artery disease underg…
A heart pump meant to protect weakened hearts during surgery may increase death risk for patients with severe heart damage, new evidence sug…
May 7, 2026
Transendocardial ProtheraCytes injections improved physical functioning and vitality in patients with recent large AMI and LV dysfunction
Cardiology RCT
Transendocardial ProtheraCytes injections improved physical functioning and vitality in patients with recent large AMI and LV dysfunction New cell injections help heart patients feel better for six months
This phase I/IIb randomized controlled trial enrolled 31 treated and 12 control patients with recent large myocardial infarction and left ve…
Patients with recent heart attacks and weak heart pumps felt significantly better physically and socially after receiving new cell injection…
May 1, 2026
Statistical Analysis Plan Defines ICD Insertion Based on Ventricular Scar for Left Ventricular Systolic Dysfunction
Cardiology
Statistical Analysis Plan Defines ICD Insertion Based on Ventricular Scar for Left Ventricular Systolic Dysfunction New Heart Scan Strategy May Reduce Sudden Death Risk
This document is a statistical analysis plan outlining methods for a trial involving patients with mild moderate left ventricular systolic d…
A new trial plan tests if heart scans can better decide who needs a life-saving device to prevent sudden cardiac death.
medRxiv Apr 29, 2026
Non-randomized preprint on dapagliflozin and epicardial adipose tissue in HFpEF
Cardiology
Non-randomized preprint on dapagliflozin and epicardial adipose tissue in HFpEF Dapagliflozin linked to fat loss in heart failure patients
This preprint reports a non-randomized clinical trial in 60 patients with left ventricular diastolic dysfunction.
Adding dapagliflozin to standard care reduced epicardial fat in a small group of heart failure patients, though this preprint study needs co…
Apr 28, 2026
Diastolic Age predicts MACE and discriminates LVDD in heart failure cohorts
Cardiology Cohort
Diastolic Age predicts MACE and discriminates LVDD in heart failure cohorts Doctors Can Now Measure Your Heart’s True Age With One Scan
This cohort study involving 1,952 participants from the Project Baseline Health Study, 1,708 from WASE, and 313 from Stanford Cardiovascular…
A new scan tool calculates your heart's biological age to spot hidden risks before symptoms appear, though it is still experimental.
medRxiv Apr 19, 2026