Research across Parkinson's Disease
Related studies from across the Parkinson's Disease family.
Photobiomodulation shows consistent anti-inflammatory effects but inconsistent clinical results in various neurodegenerative disorders
Red and near-infrared light may help certain brain disorders
This narrative review explores the role of photobiomodulation in treating Alzheimer's disease, Multiple Sclerosis, Parkinson's disease, and …
Red and near-infrared light therapy shows promise for some brain conditions, though results are mixed for others.
KRTCAP2 genetic burden and depression polygenic risk scores are associated with increased depression odds in Parkinson's
Genetic Factors Linked to Depression in Parkinson's Disease Patients
This meta-analysis of three population-based studies identifies genetic associations between specific genes and depression in Parkinson's di…
Specific genetic markers and a general risk score for depression were linked to higher rates of depression in patients with Parkinson's dise…
Transposable elements show widespread cell-type-specific dysregulation in Parkinson's substantia nigra
Transposable Elements Linked to Parkinson's Disease and Sex Differences
This meta-analysis synthesizes transposable element (TE) expression in the substantia nigra of donors with Parkinson's disease. It reports w…
New research identifies specific genetic elements that may contribute to Parkinson's disease and vary significantly between men and women.
Mind-body exercise shows largest posterior median effect for motor symptoms in Parkinson's disease
Mind-body exercise shows promise for managing Parkinson's disease symptoms
This systematic review and Bayesian network meta-analysis of 173 randomized trials evaluated exercise modalities and dose-response effects i…
Mind-body exercises may help manage motor symptoms and balance for people living with Parkinson's disease.
GALC and GBA1 loci are associated with altered enzyme activity ratios in Parkinson's disease
Genetic variants linked to enzyme balance in Parkinson's disease
This meta-analysis of genetic and enzymatic data from 1,290 individuals identifies significant associations between the GALC locus and the g…
New research identifies specific genetic markers that may affect how enzymes work together in people with Parkinson's disease.
HMGB1 acts as a progression-associated inflammatory amplifier in Alzheimer's, Parkinson's, and ALS models
New research explores a protein linked to several brain diseases
This narrative review explores the role of HMGB1 in various neurodegenerative diseases including Alzheimer's, Parkinson's, and ALS. The auth…
A specific protein called HMGB1 may act as a driver of inflammation in conditions like Alzheimer's and Parkinson's disease.
Mesenchymal stromal cells and MSC-derived extracellular vesicles may reprogram neuroimmune responses in neurodegenerative diseases
Stem cells and vesicles show potential for neurodegenerative diseases
This critical review examines the mechanisms and translational barriers of mesenchymal stromal cells (MSCs) and MSC-derived extracellular ve…
New research explores how stem cell products might protect the brain and repair blood-brain barriers in diseases like Parkinson's and Alzhei…
Exercise interventions improve motor function and freezing of gait scores in Parkinson's disease
Exercise Interventions May Improve Movement and Balance in Parkinson's
This meta-analysis of 714 patients with Parkinson's disease found that exercise interventions significantly improved motor scores and freezi…
Exercise programs may help people with Parkinson's disease improve their motor skills, balance, and symptoms like freezing of gait.
Resistance training shows largest effect for global cognition in Alzheimer's and Parkinson's disease
Resistance training shows strongest results for cognitive health in dementia
This network meta-analysis of 1,993 participants evaluated six exercise modalities for global cognitive function in Alzheimer's disease, Par…
Resistance training may offer the strongest boost to cognitive function for people living with Alzheimer's or Parkinson's disease.
Theta burst stimulation significantly improves motor symptoms and reduces depressive scores in Parkinson's disease
Theta Burst Stimulation Shows Promise for Parkinson's Disease Symptoms
This meta-analysis of 388 participants evaluates transcranial and transspinal theta burst stimulation (TBS) for Parkinson's disease. The ana…
New research suggests that theta burst stimulation may improve motor symptoms and reduce depression in people living with Parkinson's diseas…
Gut microbiota dysbiosis and increased intestinal permeability markers are associated with Parkinson's disease
Gut bacteria patterns may differ in Parkinson's disease patients
This meta-analysis of 33 human studies involving 1,588 Parkinson's disease patients and 1,449 healthy controls identifies significant altera…
New research shows specific changes in gut bacteria and intestinal barriers in people living with Parkinson's disease.
Periodontitis is associated with poorer periodontal status in patients with Parkinson's disease
Gum disease and Parkinson's disease show a linked connection
This narrative review examines the relationship between periodontitis and Parkinson's disease. While observational studies show poorer perio…
People with Parkinson's disease often have poorer gum health, but researchers say gum disease does not currently prove to cause or worsen th…