Meta-analysis of 15 observational studies links e-cigarette use to higher COPD odds
E-Cigs Linked to Higher COPD Risk Even Without Smoking
This meta-analysis of 15 observational studies assessed the association between e-cigarette use and the prevalence of chronic obstructive pu…
Using e-cigarettes today is connected to a much higher chance of developing COPD, even if you have never smoked a regular cigarette before.
Systematic review links gut-lung axis in COPD and inflammatory bowel disease
Shared genes link COPD and inflammatory bowel disease
This systematic review synthesizes evidence on shared mechanisms between COPD and inflammatory bowel disease.
A new review reveals that COPD and IBD share genetic roots, explaining why lung and gut inflammation often occur together.
mNGS on BALF samples shows higher pathogen detection in pulmonary infections vs. conventional testing
mNGS detects more lung infection pathogens than standard tests
This observational cohort study compared metagenomic next-generation sequencing (mNGS) on bronchoalveolar lavage fluid (BALF) to conventiona…
In 136 patients, mNGS found lung pathogens more often than conventional tests and better spotted mixed infections, especially in immunocompr…
Clinical-immuno-inflammatory signature for Aspergillus–Mucorales co-infection in ICU patients
ICU patients with co-infection show higher but not significant mortality
This single-center observational cohort study of 93 critically ill ICU patients found that a clinical-immuno-inflammatory signature for earl…
Critically ill patients with both Aspergillus and Mucorales infections had higher ICU mortality, but the difference was not statistically si…
FeNO measurement shows limited diagnostic performance for asthma in school-age children
FeNO breath test shows limited accuracy for diagnosing asthma in school-age children
This observational cohort study of 1,979 school-age children found that fractional exhaled nitric oxide (FeNO) had poor discrimination for a…
A breath test for asthma showed poor accuracy in children, especially those without allergies, raising questions about its use as a standalo…
De-implementation of low-value bronchiolitis practices showed sustained adherence two years post-trial in a cluster RCT follow-up
Doctors Stick to Better Bronchiolitis Care—2 Years Later
This cluster randomised controlled trial (cRCT) follow-up study assessed the sustainability of de-implementing low-value bronchiolitis pract…
It’s 2 a.m. in a busy children’s hospital.
Network meta-analysis of acupuncture interventions for acute exacerbation of chronic obstructive pulmonary disease
Acupuncture May Ease Flare-Ups in COPD, New Analysis Shows
This network meta-analysis evaluated acupuncture-related interventions versus usual treatment in 3,156 patients with acute exacerbation of c…
For people with COPD, adding specific acupuncture techniques to their usual treatment may help them breathe easier and feel better during a …
Single-center retrospective study associates ferritin and eosinophil levels with acute asthma exacerbation in children
High Iron Levels Signal Worse Asthma Attacks in Kids
This single-center retrospective study examined 120 children with asthma to identify markers associated with acute exacerbation.
Checking iron levels alongside standard asthma markers could help doctors predict dangerous flare-ups sooner.
Benralizumab reduces asthma exacerbations in severe eosinophilic asthma patients over 24 weeks
New Asthma Shot May Cut Severe Attacks to Zero
This prospective, single-arm, multicenter, phase IV study evaluated benralizumab in 138 benralizumab-naïve adults (18–75 years) with severe …
A new injection appears safe and effective at reducing severe asthma attacks in adults.
Meta-analysis identifies DNA methylation markers linked to asthma exacerbations in diverse pediatric populations
Blood Markers May Predict Severe Asthma Attacks in Kids
This meta-analysis synthesizes data from African American and Latino pediatric populations and ethnically diverse participants to evaluate D…
New research spots chemical changes in blood that signal when asthma might get dangerous.
Combined digital and paper audit feedback did not improve asthma prescribing versus digital-only in primary care
Paper Letters Add Nothing to Digital Asthma Care Plans
This cluster randomized controlled trial in 270 primary care practices in West Yorkshire compared combined digital and paper audit and feedb…
Sending printed reports to doctors does not improve asthma care more than sending emails.
Polygenic risk scores improve identification of rare variant carriers in idiopathic pulmonary fibrosis patients
Can a genetic test help spot hidden lung disease risks in pulmonary fibrosis patients?
This observational cohort study of 888 IPF patients from the PFF-PR and 472 from the UK PROFILE cohort found that polygenic risk scores (PRS…
A genetic test helps doctors spot hidden disease risks in lung patients by finding rare gene variants that standard history alone might miss…