HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.
Allergy & Immunology
Meta-analysis
Remote digital asthma management shows modest quality of life and lung function improvements in adults
Can asthma apps and websites help adults breathe easier?
A meta-analysis of 10 trials in adults with asthma found interactive remote digital management improved quality of life, symptom control, an…
Digital asthma tools show small lung function gains, but quality of life improvements were modest and didn't reach the threshold for patient…
Frontiers
Apr 2, 2026
Pulmonology & Critical Care
RCT
Acute high-intensity inspiratory muscle training linked to shorter oxygen desaturation time in COPD
Small COPD study finds different breathing exercises affect muscle oxygen differently
A randomized crossover study in 29 individuals with COPD found acute high-load IMT was associated with shorter oxygen desaturation time comp…
High-intensity breathing exercises may drop arm muscle oxygen faster than lower-intensity training in people with COPD, while endurance trai…
Apr 1, 2026
Drug Pipeline
Review proposes immunothrombosis pathway linking pulmonary disease to stroke and neurodegeneration
Researchers propose lung-to-brain inflammation pathway may link breathing problems to stroke risk
A mechanistic review integrates evidence from pulmonary medicine, coagulation biology, stroke pathology, and neurodegeneration research.
Lung inflammation might trigger clotting that travels to the brain, potentially raising stroke risk and affecting long-term brain health.
Frontiers
Apr 1, 2026
Allergy & Immunology
Sys. Review
Asia-Pacific experts propose clinical remission definition and lung function goals for severe asthma
What does it mean to beat severe asthma in Asia? Experts propose new goals
A position statement by Asia-Pacific experts reviewed severe asthma management challenges in the region.
Experts redefine severe asthma success in Asia by prioritizing symptom control and stability over impossible lung function recovery.
Frontiers
Apr 1, 2026
Cardiology
FDA Approval
FDA Approves Xarelto (rivaroxaban) for multiple indications including stroke prevention in nonvalvular atrial fibrillation and treatment of VTE
FDA approves a new blood thinner called Xarelto for several heart and clot conditions
The FDA approved rivaroxaban (Xarelto), a factor Xa inhibitor, for multiple indications including reducing stroke risk in nonvalvular atrial…
FDA approves new blood thinner Xarelto to prevent dangerous clots in heart conditions, deep vein issues, and after major surgeries.
FDA
Mar 31, 2026
Allergy & Immunology
Phase II
VALIANT: Phase 2 trial of verekitug (UPB-101) for severe asthma completes enrollment of 479 patients
Can a new injection help people with severe asthma breathe easier and avoid dangerous flare-ups?
The VALIANT study, a phase 2 trial, evaluated the efficacy and safety of subcutaneous verekitug (UPB-101) versus placebo in adults with seve…
A new asthma injection aims to reduce dangerous flare-ups and improve breathing for adults with severe asthma in a completed trial.
CT.gov
Mar 30, 2026
Allergy & Immunology
Phase III
Pink vs. white inhaler actuators studied for asthma symptom perception in crossover trial
Study compares pink and white asthma inhalers for how patients perceive symptoms
A phase IIIb randomized, double-blind, crossover trial in 78 adults with moderate to severe asthma compared identical beclomethasone/formote…
Asthma patients tried identical inhalers in pink or white to see if color changed how they perceived their symptoms and which device they pr…
CT.gov
Mar 30, 2026
Allergy & Immunology
Phase II
Phase 2 trial tests amlitelimab add-on therapy in adults with moderate-to-severe asthma
Phase 2 trial tests new asthma drug amlitelimab in adults with moderate-to-severe asthma
A phase 2 randomized controlled trial enrolled 437 adults with moderate-to-severe asthma globally to evaluate amlitelimab versus placebo.
A new asthma drug called amlitelimab is being tested to see if adding it to current treatments can reduce severe asthma attacks in adults wi…
CT.gov
Mar 30, 2026
Oncology
RCT
Home treatment for low-risk cancer-associated PE shows 4.6% major bleeding rate in ONCO PE companion report
Could some cancer patients safely treat blood clots at home? New research suggests yes
A predetermined companion report from the ONCO PE trial evaluated 3-month outcomes for home vs.
Active cancer patients with low-risk lung clots can safely take blood thinners at home, avoiding disruptive hospital stays while staying on …
Mar 30, 2026
Allergy & Immunology
Phase IV
Digital albuterol system feasibility studied in 333 asthma patients with suboptimal control
Can a smart inhaler help people with uncontrolled asthma breathe easier?
A phase 4, open-label, multicenter feasibility study randomized 333 participants aged 13+ with suboptimal asthma control to either the Albut…
A new smart inhaler system tested for 12 weeks to see if it helps people with uncontrolled asthma breathe easier, but results are not yet av…
CT.gov
Mar 30, 2026
Pediatrics
RCT
Nurse-driven HFNC weaning protocol cuts therapy duration by 16 hours, hospital stay by 1 day in bronchiolitis infants
Can letting nurses decide when to reduce breathing support help babies with bronchiolitis get home faster?
In infants with severe bronchiolitis, a nurse-driven high-flow nasal cannula (HFNC) weaning protocol significantly reduced median HFNC durat…
A nurse-driven checklist helped babies with severe bronchiolitis get off breathing support 34 hours sooner, cut hospital stays, and kept the…
Mar 30, 2026
Allergy & Immunology
Phase II
Phase 2 Study Evaluates Brenipatide for Moderate-to-Severe Asthma
Could a new drug help people with severe asthma breathe easier?
A Phase 2 trial is assessing the safety and efficacy of brenipatide versus placebo in 531 participants with moderate-to-severe asthma.
A new asthma drug trial aims to reduce flare-ups and improve breathing for adults with moderate-to-severe asthma over the next year.
CT.gov
Mar 28, 2026