How many clinical trials are tracked for nasal obstruction?

11 trials are tracked, 1 with published results.

nasal obstruction Research

Nasal obstruction: what the trials found

Interventions for nasal obstruction include the use of the Vivaer Stylus, which demonstrated significant improvements in Nasal Obstruction Symptom Evaluation (NOSE) scores. Specifically, studies reported mean reductions in NOSE scores ranging from -44.5 ⁷ to -53.3 ⁹, with high responder rates noted in multiple trials [9, 11]. Long-term follow-up for the Vivaer Stylus showed sustained improvements in NOSE scores of 25.7 and 32.3 ⁹.

Nasal implants have been shown to significantly reduce nasal airway obstruction as measured by a Visual Analog Scale (VAS) with mean reductions between -34.3 and -41.7 (p<0.001) ⁸. Additionally, nasal implants demonstrated high responder rates in clinical evaluations, reaching up to 147% in certain cohorts [8, 10].

In contrast, pharmacological management with Triamcinolone Acetonide did not result in a statistically significant difference in NOSE scores compared to a placebo saline spray (p=0.7) ². However, patients who underwent surgery following the initial treatment period showed significant improvements in NOSE scores compared to pre-surgical levels (p<0.001) ².

For the clinician treating this condition

The Vivaer Stylus is associated with significant and sustained reductions in NOSE scores for nasal obstruction [7, 9, 11].
Nasal implants provide statistically significant improvements in airway obstruction as measured by VAS ⁸ and high responder rates ¹⁰.
Triamcinolone Acetonide did not show superior efficacy over saline spray for NOSE scores, though surgical intervention following medical therapy showed significant improvement ².

AI synthesis of 8 cited trials, updated Jun 25, 2026. Informational only — not medical advice; trial data sourced from ClinicalTrials.gov. How we use AI.