mRNA-1010 shows superior efficacy against influenza in older adults
New flu shot cuts illness by 27 percent in adults over 50
A phase 3 trial found mRNA-1010 vaccine had 26.6% relative efficacy versus standard comparator in adults 50+.
A new mRNA flu vaccine reduced confirmed flu illness by 27 percent compared with the standard shot in adults 50 and older.
Six H5N1 vaccine formulations showed immunogenicity and acceptable safety in 420 healthy children aged 6 months to 9 years
Higher adjuvant content boosts immunity in children without added safety risks
This phase 2, observer-blind, multicenter study evaluated six formulations of MF59-adjuvanted H5N1 vaccine in 420 healthy infants and childr…
A Phase 2 trial in healthy children found that higher adjuvant content improved immune responses to an H5N1 vaccine without increasing side …
Systematic review and meta-analysis finds bacterial co-infection in 17.3% of hospitalized influenza patients
Hospital data shows high rates of bacterial co-infection in influenza patients
This systematic review and meta-analysis of 111,889 hospital-attended patients with laboratory-confirmed influenza found a pooled prevalence…
Analysis of over 111,000 patients reveals that bacterial co-infection occurs in 17.3% of hospital cases with confirmed influenza infection.
Coadministration of RSV mRNA vaccine and high-dose flu vaccine noninferior for flu but not for RSV in older adults
New data shows RSV and flu shots work well together
This phase 3 randomized controlled trial in 1900 adults aged 65 and older compared coadministration of mRNA-1345 and quadrivalent influenza …
Older adults can now get their RSV and flu vaccines during one visit without safety risks or extra trips to the clinic for care.
Survey finds physicians show stronger intergroup bias than public on vaccines
Doctors Show Strong Bias Against Vaccine-Hesitant Patients
This review of an online survey in Japan involving 492 physicians and 5,252 members of the general public found that physicians exhibited hi…
Doctors often see themselves as targets of vaccine anger, but new data shows they also hold strong bias against patients who question vaccin…
Systematic review synthesizes Rhaponticum species chemistry, traditional uses, and research gaps across multiple conditions
Ancient Herbs May Help Modern Health
This systematic review synthesizes data on Rhaponticum species, covering 24 documented species worldwide and their applications for conditio…
Imagine walking through a garden filled with wildflowers.
Infection status associated with hypoxemia and death rates varying by virus type in a large US cohort
Triple Virus Infections Rarer Than Feared — Here’s the Real Risk
This cohort study of 835,987 triple-tested patients in the US Veterans Health Administration examined associations between infection status …
It’s winter. Your throat is scratchy. Your chest feels tight.
Narrative review outlines VLP engineering strategies for broadly protective vaccines against multiple viral pathogens
New Vaccine Map Helps Pick Best Tools
This narrative review examines virus-like particle (VLP) engineering strategies, including genetic fusion, modular conjugation, and nucleic …
Imagine trying to fix a leaky roof with every tool in the shed.
EBOV-specific gene signature identified in nonhuman primates and human cohorts with Ebola infection
New gene signature can spot Ebola infection in blood samples
This observational cohort study analyzed RNA-Seq data from nonhuman primates and human cohorts with Ebola virus infection and comparator inf…
Researchers found a 50-gene signature that reliably separates Ebola from other infections in blood tests, pointing to a future diagnostic to…
Review of intranasal influenza vaccines compared to intramuscular seasonal vaccines
Your Next Flu Vaccine Might Come From Your Nose
This review evaluates intranasal influenza vaccine platforms, including licensed and emerging replicating and non-replicating types, against…
New flu sprays target the virus at your nose and throat, aiming to stop infection before it enters your body for better protection.
Methodological review assesses phenotypes for classifying respiratory viruses in English health data
How Doctors Track RSV, Flu, and COVID When Tests Aren't Always Done
This methodological review evaluates phenotypes for classifying respiratory viruses like RSV, influenza, and COVID-19 in English coded healt…
Coded health records can now identify RSV, flu, and COVID-19 outbreaks without lab tests, helping public health agencies track disease trend…
Mini-review examines MRSA-influenza co-infection pathogenesis and adjunctive therapies
Flu Damage Lets Bacteria Destroy Your Lungs
A mini-review examines the pathogenesis of MRSA-influenza co-infection, noting influenza damages respiratory epithelium and facilitates S.
Flu damage breaks your lung's protective shield, letting bacteria multiply and destroy healthy tissue to cause severe pneumonia.