Research across Cancer
Related studies from across the Cancer family.
Immunonutrition may improve management of radiation-induced oral mucositis in head and neck cancer patients
Immunonutrition may help manage mouth sores in head and neck cancer
This narrative review examines the role of immunonutrition for managing oral mucositis in patients with head and neck malignancies undergoin…
Patients with head and neck cancer often suffer from painful mouth sores. New evidence suggests immunonutrition could help manage these symp…
Postoperative radiotherapy reduces local and peristomal recurrence rates in laryngeal cancer patients with preoperative tracheotomy
Radiotherapy May Lower Recurrence Risk After Laryngectomy for Cancer
This meta-analysis of 4339 patients evaluates the impact of postoperative radiotherapy (PORT) on recurrence rates following total laryngecto…
Postoperative radiotherapy may lower the risk of cancer returning in the throat area for patients who had a tracheotomy before surgery.
Zygomatic implants provide high survival rates for maxillary reconstruction in head and neck cancer patients
Zygomatic implants show high survival for head and neck cancer
This systematic review and meta-analysis of 294 patients with extensive maxillary defects found a 97% overall implant survival rate. The ana…
New data shows zygomatic implants have a 97% survival rate, offering a reliable way to restore jaw function after cancer surgery.
AI diagnostic tools show high accuracy but limited real-world validation in systematic review
Artificial intelligence shows high accuracy in detecting various medical conditions
This systematic review of 24 studies synthesizes evidence on AI and deep learning for disease detection across multiple imaging modalities. …
New analysis of 24 studies shows AI tools can reach over 90% accuracy in spotting everything from lung cancer to skin disorders.
Prophylactic PEG tube placement improves nutritional status and reduces hospitalizations for head and neck cancer patients
Proactive Feeding Tubes May Improve Support for Head and Neck Cancer
This meta-analysis of 1279 patients evaluates prophylactic versus reactive percutaneous endoscopic gastrostomy (PEG) tubes in head and neck …
Early placement of feeding tubes may improve nutritional stability and reduce hospital stays for patients undergoing head and neck cancer tr…
High PTTG1 expression correlates with poorer survival and advanced disease in various solid tumors
High levels of PTTG1 protein linked to worse cancer outcomes
This meta-analysis of 22 studies from 21 articles analyzed the prognostic value of PTTG1 expression across multiple solid tumors. High PTTG1…
A review of 22 studies shows that high levels of the PTTG1 protein are linked to shorter survival times in several types of solid tumors.
Zinc supplementation shows potential in reducing severe radiation-induced oral mucositis in head and neck cancer patients
Zinc Mouthwash May Reduce Severe Mouth Sores From Radiation
Researchers evaluated the impact of topical and systemic zinc on the incidence of severe radiation-induced oral mucositis in head and neck c…
A new analysis suggests zinc mouthwash may cut the risk of severe mouth sores from radiation by 84%.
Metabolic reprogramming of lipid-associated macrophages creates an immunosuppressive microenvironment in pancreatic ductal adenocarcinoma
Specific immune cells help pancreatic cancer grow and spread
This narrative review characterizes the role of lipid-associated macrophages (LAMs) and their metabolic pathways in the pancreatic ductal ad…
Researchers identified how specific fat-loving immune cells create a shield that protects pancreatic tumors from the body's natural defenses…
Advanced experimental models and computational tools provide dynamic frameworks for understanding oral disease progression
New Research Tools Help Map Complex Oral Diseases
This mini-review examines the integration of advanced experimental models, such as organ-on-chip systems and patient-derived organoids, with…
Advanced modeling and AI tools are helping researchers better understand the molecular causes behind conditions like gum disease and oral ca…
Microbial metabolites may promote or suppress cancer progression through inflammation, DNA damage, or immune modulation
Microbial metabolites may drive cancer growth or stop it through inflammation and DNA damage
This narrative review examines the role of microbial metabolites in carcinogenesis and cancer progression across multiple malignancies. The …
Microbial metabolites can promote cancer growth via inflammation or suppress it through immune changes, but we need more proof before using …
Aspiration pneumonia affects 74.8% of head and neck cancer patients after chemoradiotherapy
Aspiration pneumonia strikes most head and neck cancer patients after chemoradiation
This supplementary analysis of a phase II/III trial in Japan found that 74.8% of 151 patients with resected high-risk head and neck cancer d…
Three in four head and neck cancer patients develop aspiration pneumonia after chemoradiation. Severe swallowing problems and reconstruction…
Radiotherapy and chemotherapy show no clear link to obstructive sleep apnea in head and neck cancer patients
Radiation for head and neck cancer may raise sleep apnea risk
This scoping review with exploratory meta-analysis of 13 studies found no significant association between radiotherapy or chemotherapy and i…
A review of 13 studies suggests a possible link between radiation for head and neck cancer and mild sleep apnea, but the evidence is too wea…