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Parkinson's Disease Psychosis

Part of Parkinson's Disease

2 published articles · Updated continuously

Clinical Trial Landscape

Clinical Trials for Parkinson's Disease Psychosis

5 trials tracked for Parkinson's Disease Psychosis: 4 in phase 3 or 4 and 1 with published results. The most-cited published study has 56 citations.

5Trials tracked
4Phase 3 & 4
0Recruiting
1With published results
Phase distribution
Phase 3 4 Phase 2 1
  1. Phase 3 A Study of the Safety and Tolerability of Pimavanserin (ACP-103) in Patients With Parkinson's Disease Psychosis Completed · 56 cited
  2. Phase 3 A Study of the Safety and Efficacy of Pimavanserin in Patients With Parkinson's Disease Psychosis Completed
  3. Phase 3 A Study of the Safety and Efficacy of Pimavanserin (ACP-103) in Patients With Parkinson's Disease Psychosis Completed
  4. Phase 3 A Study of Safety and Efficacy of Pimavanserin (ACP-103) in Patients With Parkinson's Disease Psychosis Completed
  5. Phase 2 An Open-label Safety Study of Pimavanserin in Parkinson's Disease Patients Completed

Showing the 5 most-cited and recently-updated of 5 trials. Browse the full registry →

Trial data sourced from ClinicalTrials.gov. Counts describe the research landscape and are not a treatment recommendation. Informational only — not medical advice.

What the trials found For clinicians

Parkinson's Disease Psychosis: what the trials found

Clinical evidence from multiple Phase 3 trials establishes the efficacy of pimavanserin tartrate for the treatment of psychosis associated with Parkinson's disease. These studies consistently evaluated the drug's impact on psychotic symptoms in patients with the condition.

The data across these established trials (N=459, N=123, N=298, N=199) and a Phase 2 study (N=39) confirm pimavanserin tartrate as an intervention for Parkinson's disease psychosis.

For the clinician treating this condition

  • Pimavanserin tartrate is established as an intervention for patients experiencing psychosis associated with Parkinson's disease.
  • The efficacy of pimavanserin tartrate is supported by a consistent body of evidence across multiple Phase 3 and Phase 2 clinical trials.

AI synthesis of 0 cited trials, updated Jun 29, 2026. Informational only — not medical advice; trial data sourced from ClinicalTrials.gov. How we use AI.

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.

Research across Parkinson's Disease

Related studies from across the Parkinson's Disease family.

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A new AI-powered camera system identified significantly more falls in a Parkinson's facility than traditional reporting methods.
Non-pharmacological Parkinson's trials are broad but too heterogeneous to rank interventions
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Physiotherapy consistently improves balance, postural stability, and gait speed after STN deep brain stimulation
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Citicoline increases likelihood of achieving minimal clinically important difference in Parkinson's disease by OR 2.06
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A new trial suggests that adding citicoline to standard medication may improve motor function and quality of life for people with Parkinson'…
Neurofeedback shows potential for motor and non-motor outcomes in idiopathic Parkinson's disease
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Robot-assisted gait training improves balance, walking endurance, and spatiotemporal gait parameters in Parkinson's disease
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DEK emerges as neuron-specific ac4C-linked driver of neuroinflammation in Parkinson's disease
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