FDA Approves Nuplazid (pimavanserin) for Parkinson's Disease Psychosis
FDA approves first drug for hallucinations in Parkinson's disease
The FDA approved Nuplazid (pimavanserin) for hallucinations and delusions associated with Parkinson's disease psychosis. Approval was based …
The FDA approved Nuplazid (pimavanserin) to treat hallucinations and delusions in people with Parkinson's disease psychosis. It is the first…
FDA Approves Nuplazid (pimavanserin) for Parkinson's Disease Psychosis
FDA approves first drug for hallucinations in Parkinson's disease
FDA approved Nuplazid (pimavanserin) for hallucinations and delusions associated with Parkinson's disease psychosis. In a 6-week trial, Nupl…
The FDA approved Nuplazid (pimavanserin) to treat hallucinations and delusions in people with Parkinson's disease psychosis. It is the first…
Research across Parkinson's Disease
Related studies from across the Parkinson's Disease family.
Gut microbial metabolites modulate neural homeostasis and influence neuroinflammation in several neurological and psychiatric disorders
Gut Metabolites May Influence Alzheimer's and Parkinson's Disease
This narrative review explores how gut microbial metabolites, including short-chain fatty acids, tryptophan metabolites, and bile acids, inf…
Gut microbes produce metabolites that may influence brain health and impact conditions like Alzheimer's, Parkinson's, and chronic insomnia.
Clinical Parkinson's diagnosis improves from 57% to 87% sensitivity between initial and final assessment
New data shows how doctors diagnose Parkinson's disease accurately
This meta-analysis of 9659 patients with Parkinson's disease examined the diagnostic accuracy of clinical criteria (UKPDSBB, Gelb, MDS-PD 20…
Diagnosing Parkinson's disease early is difficult, but new data shows how specific clinical criteria improve accuracy as the disease progres…
Tavapadon improves motor and functional outcomes in Parkinson's disease but raises adverse event risk
Tavapadon Eases Parkinson's Motor Symptoms in Early Analysis
This meta-analysis pools data on tavapadon in Parkinson's disease and reports improvements in combined MDS-UPDRS Parts II + III (MD -8.80), …
A new Parkinson's drug, tavapadon, improved movement and daily function scores, but it also raised the risk of treatment-related side effect…
Virtual reality training improves functional mobility and balance confidence in patients with Parkinson's disease
Virtual reality training improves balance and mobility in Parkinson's disease
This meta-analysis of 1110 patients found that virtual reality training (VRT) significantly improves functional mobility (TUG) and balance c…
Virtual reality training can improve balance confidence and mobility for people living with Parkinson's disease.
Resistance and balance training significantly improve motor symptoms and quality of life in Parkinson's disease
Exercise Programs Help Manage Movement and Balance for People with Parkinson's
This meta-analysis of 391 patients found that resistance training, balance training, or combined interventions significantly improved motor …
New data shows that strength and balance training can significantly improve daily movement and mood for those living with Parkinson's diseas…
Mirabegron and onabotulinumtoxinA reduce urinary frequency and nocturia in patients with Parkinson's disease and overactive bladder
New data shows mirabegron and Botox help Parkinson's bladder issues
This meta-analysis evaluates the efficacy of mirabegron and intradetrusor onabotulinumtoxinA for managing overactive bladder in patients wit…
New research shows that mirabegron and Botox injections can reduce frequent urination and bladder urgency for people with Parkinson's diseas…
Deep brain stimulation significantly improves symptoms in obsessive-compulsive disorder and Gilles-de-la-Tourette syndrome
Trial shows Deep Brain Stimulation helps OCD and Tourette Syndrome
This meta-analysis of 28 studies evaluates deep brain stimulation (DBS) compared to sham DBS across various psychiatric and neurological con…
Deep brain stimulation shows significant promise for treating OCD and Tourette syndrome, according to a review of 28 different clinical stud…
Patients with Parkinson's disease exhibit deficits in sustained, selective, and divided visuospatial attention
Parkinson's Disease Linked to Specific Visuospatial Attention Deficits
This meta-analysis of 51 studies evaluates visuospatial attention in cognitively unimpaired patients with Parkinson's disease. The analysis …
New research identifies specific ways Parkinson's disease affects how the brain processes and directs attention in space.
Right inferior frontal gyrus serves as a consistent neural correlate for freezing of gait
Brain activity in specific regions linked to Parkinson's gait freezing
This meta-analysis of 33 studies identifies the right inferior frontal gyrus (IFG) as a consistent neural correlate for freezing of gait in …
New data identifies a specific area in the brain linked to the sudden freezing of movement in people with Parkinson's disease.
Gut microbiota-associated signals may influence immune homeostasis and neuroinflammation in neurodegenerative diseases
Gut bacteria may influence immune health in the central nervous system
This systematic review explores how gut microbiota-associated signals, including short-chain fatty acids and bile acids, may influence immun…
Gut bacteria and their byproducts may influence immune responses and inflammation in the brain, potentially impacting several neurodegenerat…
Neuromelanin-sensitive MRI shows significant group-level differences in LC signal and volume in Parkinson's disease
MRI Imaging Shows Distinct Changes in Parkinson's Disease Patients
This meta-analysis of 1,078 participants with Parkinson's disease and 543 healthy controls found significantly lower LC signal (Hedges' g = …
New imaging data shows significant differences in brain signals for people with Parkinson's disease compared to healthy individuals.
STN-SNr co-stimulation adds no motor or gait benefit over STN-only in Parkinson's
Trial shows no added benefit for specific Parkinson's brain stimulation
This meta-analysis of 10 studies (109 evaluable participants) found no between-group difference for STN-SNr co-stimulation versus STN-only s…
New analysis shows that adding a second stimulation point in the brain does not improve movement for Parkinson's patients.