Mode
Home
Research
Clinical Trials Drug Pipeline Weekly Digests
Reference
Conditions Medications
Community
Questions
Text Size
Log in / Sign up
Home › Conditions › Pelvic floor disorders

Pelvic floor disorders

1 published article · Updated continuously

Clinical Trial Landscape

Clinical Trials for Pelvic floor disorders

14 trials tracked for Pelvic floor disorders: 4 in phase 3 or 4 and 2 with published results. The most-cited published study has 23 citations.

14Trials tracked
4Phase 3 & 4
0Recruiting
2With published results
Phase distribution
Phase 4 2 Phase 3 2 Phase 2 1 Other / NA 9
  1. Phase 4 Investigation to Minimize Prolapse Recurrence of the Vagina Using Estrogen Completed · 23 cited
  2. Phase 3 Chlorhexidine vs. Iodine for Vaginal Preparation in Urogynecologic Procedures Completed · 9 cited
  3. Phase 4 Lessons on Urethral Lidocaine in Urodynamics Completed
  4. Phase 3 Platelet Rich Plasma in Levator Ani Muscle Trauma Completed
  5. Phase 2 Vaginal Diazepam for the Treatment of Female Pelvic Pain Completed
  6. N/A Correlation of Anal Acoustic Reflectometry Parameters With Degree of Rectal Intussusception and Prolapse Completed
Show 8 more trials
  1. N/A Lubricant Versus Lidocaine Gel for Pain Control During Urodynamics Completed
  2. N/A Satisfaction of Limited English-Proficient Patients With Phone Interpretation Services Compared to In-Person Interpreters: A Randomized Controlled Trial Completed
  3. N/A Educating Women About Pelvic Floor Disorders During Pregnancy Completed
  4. N/A Retropubic vs. Single-Incision Mid-Urethral Sling for Stress Urinary Incontinence Completed
  5. N/A Viewing Surface Electrical Stimulation on Pelvic Floor With Ultrasound Completed
  6. N/A Pelvic Floor Physical Therapy vs Standard Care in Transgender Women Undergoing Vaginoplasty for Gender Affirmation Completed
  7. N/A Does a Patient Education Video Augment Pelvic Floor Physical Therapy Compliance? Completed
  8. N/A Pudendal Nerve Block in Vaginal Surgery Completed

Showing the 14 most-cited and recently-updated of 14 trials. Browse the full registry →

Trial data sourced from ClinicalTrials.gov. Counts describe the research landscape and are not a treatment recommendation. Informational only — not medical advice.

What the trials found For clinicians

Pelvic floor disorders: what the trials found

Clinical evidence for pelvic floor disorders includes the use of Conjugated Estrogens Cream 1. Additionally, a vaginal scrub applied vaginally and perineally immediately prior to surgery has been evaluated as an intervention 3.

The use of Water-Based Vaginal Lubricant was associated with specific voiding metrics, specifically a percentage of Voiding Efficiency of 94.6 and 95.9 2.

Recent results — preliminary, needs further review

  • Diazepam showed no statistically significant difference in Visual Analog Scale (VAS) for pain (p=0.62), Pelvic Floor Distress Inventory-20 scores (p=0.66), or McGill Pain Questionnaire scores (p=0.88) 5.
  • Platelet Rich Plasma was evaluated regarding Levator Hiatal Area during Valsava and Pelvic Floor Muscle Contraction, but neither metric showed statistically significant changes (p=0.086 and p=0.29 respectively) 4.
  • In-person interpretation modality was associated with a statistically significant difference in patient satisfaction (p=0.002) 11.

For the clinician treating this condition

  • Conjugated Estrogens Cream and pre-surgical vaginal scrubs are established interventions for pelvic floor conditions [1, 3].
  • Water-Based Vaginal Lubricant is associated with specific voiding efficiency metrics 2.
  • Platelet Rich Plasma did not demonstrate statistically significant changes in levator hiatal area or muscle contraction during Valsava maneuvers 4.

AI synthesis of 6 cited trials, updated Jul 21, 2026. Informational only — not medical advice; trial data sourced from ClinicalTrials.gov. How we use AI.

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.
Diffusion tensor imaging metrics may improve diagnostic specificity for pelvic floor anatomical conditions
OB/GYN & Women's Health Meta-analysis
Diffusion tensor imaging metrics may improve diagnostic specificity for pelvic floor anatomical conditions DTI scans show promise for pelvic floor conditions
This systematic review of 30 studies evaluates diffusion tensor imaging (DTI) for assessing tissue microstructural disruption in pelvic stru…
A review of 30 studies finds DTI may help diagnose anal fistula, endometriosis, fibroids, and prostate cancer.
Frontiers Jun 20, 2026