Berberine exhibits antimicrobial and anti-inflammatory effects for managing various oral mucosal and dental conditions
Berberine Shows Potential for Treating Various Oral Health Conditions
This systematic review synthesizes the pharmacological properties of berberine in treating oral diseases including periodontitis, caries, an…
A review of berberine suggests it may help manage oral diseases like periodontitis and dental caries through its anti-inflammatory and antio…
Shared molecular pathways and hub genes link endocrine disorders with periodontitis progression
Shared Molecular Pathways Link Endocrine Disorders and Periodontitis
This narrative review synthesizes the molecular mechanisms underlying the crosstalk between endocrine disorders and periodntis. It identifie…
New research identifies shared biological pathways that link endocrine disorders with gum disease, potentially changing how doctors treat bo…
Magnesium phosphate cements demonstrate superior biological interactions and faster resorption than calcium phosphate cements
Magnesium Phosphate Cements Show Better Biological Interaction Than Calcium Options
This mini review examines the properties of magnesium phosphate cements (MPCs) compared to calcium phosphate cements (CPCs). The authors con…
New research suggests magnesium phosphate cements may offer better biological interactions and faster resorption than traditional calcium ph…
Physical exercise may attenuate inflammation and alveolar bone loss in patients with periodontitis
Exercise May Help Reduce Inflammation and Bone Loss in Periodontitis
This scoping review of 23 studies examines the impact of physical exercise on inflammation and alveolar bone loss in humans and rodents. The…
New research suggests that regular physical exercise may help reduce inflammation and bone loss for people living with gum disease.
Oral diseases stem from disrupted host-microbiome-immune balance, narrative review argues
New research explores how oral bacteria drive gum disease
This narrative review argues that periodontitis, dental caries, and oral squamous cell carcinoma should be understood as disorders of host-m…
Oral health depends on a delicate balance between your immune system, tissue barriers, and the trillions of microbes living in your mouth.
Plant essential oils demonstrate significant inhibitory effects against key subgingival plaque microbial complexes in periodontitis
Plant essential oils show promise against gum disease bacteria
This systematic review synthesizes the antibacterial activity of plant essential oils, including carvacrol and thymol, against subgingival p…
Certain plant oils may fight the specific bacteria that cause periodontitis while also helping to block harmful biofilm from forming in the …
Advanced experimental models and computational tools provide dynamic frameworks for understanding oral disease progression
New Research Tools Help Map Complex Oral Diseases
This mini-review examines the integration of advanced experimental models, such as organ-on-chip systems and patient-derived organoids, with…
Advanced modeling and AI tools are helping researchers better understand the molecular causes behind conditions like gum disease and oral ca…
Periodontal disease is associated with a 2.67 odds ratio for Alzheimer's disease
Gum disease linked to higher Alzheimer's risk in large analysis
This meta-analysis of 291,057 participants identified a significant association between periodontal disease and Alzheimer's disease (OR = 2.…
A large analysis of 291,057 people found that gum disease is linked to nearly 3 times higher odds of Alzheimer's disease, but more research …
Periodontitis and chronic liver disease linked through proposed oral-gut-liver axis
Conceptual framework links liver, gut, immune, and oral health
This narrative review proposes a Liver-Gut-Immune-Oral Axis linking periodontitis and chronic liver disease. The authors synthesize mechanis…
A narrative review suggests a conceptual link between liver disease and oral health, though this biological system needs direct experimental…
Meta-analysis of 16 trials shows no added benefit of subgingival chemical irrigation for periodontitis
Deep cleaning your gums? That extra rinse may not help at all
This systematic review and meta-analysis evaluated 16 randomized clinical trials comparing subgingival irrigation with chemical agents versu…
If you have gum disease and your dentist suggests a special rinse during a deep cleaning, new research says it probably won't make a differe…
Narrative review of oxidative stress and antioxidant defense in periodontitis and peri-implantitis
Oxidative stress may drive gum disease and bone loss
This narrative review examines the role of oxidative stress and antioxidant defense systems in periodontitis and peri-implantitis.
New evidence suggests that an imbalance in your body's antioxidant defenses could play a major role in how gum disease progresses.
Narrative review examines links between periodontitis and systemic disorders without claiming causation
Oral inflammation may link to systemic disorders, but evidence is not definitive
This narrative review explores the relationship between oral inflammatory diseases, particularly periodontitis, and various systemic disorde…
A narrative review suggests oral inflammatory diseases like periodontitis are associated with systemic disorders, though the evidence is not…
Questions about Periodontal Disease
What is the link between Periodontal Disease and Alzheimer's disease risk?
Periodontal disease is linked to a higher risk of Alzheimer's disease, likely through inflammation and oral bacteria reaching the brain, but a direct cause is not proven.
Full answer →Is there a link between Periodontal Disease and pancreatic cancer in older adults?
Yes, research suggests periodontal disease is linked to a higher risk of pancreatic cancer in older adults, possibly due to chronic inflammation and oral bacteria.
Full answer →All Periodontal Disease Articles
- Berberine exhibits antimicrobial and anti-inflammatory effects for managing various oral mucosal and dental conditions
- Magnesium phosphate cements demonstrate superior biological interactions and faster resorption than calcium phosphate cements
- Shared molecular pathways and hub genes link endocrine disorders with periodontitis progression
- Physical exercise may attenuate inflammation and alveolar bone loss in patients with periodontitis
- Oral diseases stem from disrupted host-microbiome-immune balance, narrative review argues
- Plant essential oils demonstrate significant inhibitory effects against key subgingival plaque microbial complexes in periodontitis
- Advanced experimental models and computational tools provide dynamic frameworks for understanding oral disease progression
- Periodontal disease is associated with a 2.67 odds ratio for Alzheimer's disease
- Periodontitis and chronic liver disease linked through proposed oral-gut-liver axis
- Meta-analysis of 16 trials shows no added benefit of subgingival chemical irrigation for periodontitis
- Narrative review of oxidative stress and antioxidant defense in periodontitis and peri-implantitis
- Narrative review examines links between periodontitis and systemic disorders without claiming causation
- Narrative review offers theoretical framework for precision interventions in periodontitis and peri-implantitis based on the neuro-osteo-immune axis
- Periodontal disease linked to increased pancreatic cancer risk in middle-aged and elderly individuals
- Oral microbiome profiles differ by periodontitis stage in Korean adults
- Kangfuxin solution improves implant outcomes in chronic periodontitis patients
- Systematic review links periodontitis to NAFLD progression and HCC risk
- Review links periodontitis to higher cardiovascular risk but notes causal inference is unproven
- Anodized versus machined implant abutments: histologic signs of improved peri-implant soft tissue healing
- Mini-review examines nanomaterial strategies for managing implant-associated oral biofilms
- Older adults with fewer than 20 teeth have 3.6 times higher odds of frailty in meta-analysis
- Adjunctive antibiotics in peri-implantitis surgery reduce bleeding on probing but not other outcomes
- Narrative review explores interkingdom interactions in subgingival microbiome and periodontitis
- Periodontal disease associated with increased oral cancer odds in meta-analysis of case-control studies
- High Infection Rates in Type 2 Diabetes: Periodontitis Prevalence at 33.6%