HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.
Allergy & Immunology
Sys. Review
Periodontitis and chronic liver disease linked through proposed oral-gut-liver axis
Conceptual framework links liver, gut, immune, and oral health
This narrative review proposes a Liver-Gut-Immune-Oral Axis linking periodontitis and chronic liver disease. The authors synthesize mechanis…
A narrative review suggests a conceptual link between liver disease and oral health, though this biological system needs direct experimental…
Frontiers
Jun 4, 2026
Physical Medicine & Rehab
Meta-analysis
Meta-analysis of 16 trials shows no added benefit of subgingival chemical irrigation for periodontitis
Deep cleaning your gums? That extra rinse may not help at all
This systematic review and meta-analysis evaluated 16 randomized clinical trials comparing subgingival irrigation with chemical agents versu…
If you have gum disease and your dentist suggests a special rinse during a deep cleaning, new research says it probably won't make a differe…
May 13, 2026
Gastroenterology
Sys. Review
Narrative review of oxidative stress and antioxidant defense in periodontitis and peri-implantitis
Oxidative stress may drive gum disease and bone loss
This narrative review examines the role of oxidative stress and antioxidant defense systems in periodontitis and peri-implantitis.
New evidence suggests that an imbalance in your body's antioxidant defenses could play a major role in how gum disease progresses.
Frontiers
Apr 30, 2026
Gastroenterology
Sys. Review
Narrative review examines links between periodontitis and systemic disorders without claiming causation
Oral inflammation may link to systemic disorders, but evidence is not definitive
This narrative review explores the relationship between oral inflammatory diseases, particularly periodontitis, and various systemic disorde…
A narrative review suggests oral inflammatory diseases like periodontitis are associated with systemic disorders, though the evidence is not…
Frontiers
Apr 29, 2026
Diabetes & Endocrinology
Cohort
Narrative review offers theoretical framework for precision interventions in periodontitis and peri-implantitis based on the neuro-osteo-immune axis
1. HEADLINE
This narrative review provides a theoretical framework for future precision interventions in oral inflammatory diseases based on the neuro-o…
Nerves explain why implants lose bone faster than
Frontiers
Apr 29, 2026
Gastroenterology
Cohort
Oral microbiome profiles differ by periodontitis stage in Korean adults
Gum disease severity linked to specific oral bacteria in Korean adults
This pilot prospective cross-sectional study of 74 Korean adults assessed oral microbiome profiles by periodontitis stage.
Severe gum disease in Korean adults shows a unique bacterial pattern, pointing to future microbiome-based diagnostic tools.
Frontiers
Apr 27, 2026
Infectious Disease
Cohort
Periodontal disease linked to increased pancreatic cancer risk in middle-aged and elderly individuals
Bad gums could raise your risk for deadly pancreatic cancer
This review of epidemiological studies found an association between periodontal disease and increased risk of pancreatic cancer incidence an…
Your mouth health might hold the key to preventing a deadly form of cancer that often goes unnoticed until it is too late.
Frontiers
Apr 27, 2026
Gastroenterology
Sys. Review
Systematic review links periodontitis to NAFLD progression and HCC risk
Your Mouth Could Be Harming Your Liver—Here’s What to Do
This systematic review finds that periodontitis and oral pathogens like F.
You brush your teeth every day. You might floss sometimes.
Frontiers
Apr 23, 2026
Rheumatology
Cohort
Kangfuxin solution improves implant outcomes in chronic periodontitis patients
New Mouthwash Cuts Implant Problems by 75%
This retrospective cohort study of 300 chronic periodontitis patients found that implant rehabilitation with adjunctive Kangfuxin solution f…
This rinse could help thousands keep dental implants longer.
Frontiers
Apr 23, 2026
Cardiology
Sys. Review
Review links periodontitis to higher cardiovascular risk but notes causal inference is unproven
Does gum disease truly raise your risk for heart attacks and strokes?
This narrative review synthesizes evidence regarding the association between periodontitis and atherosclerotic cardiovascular disease, coron…
Severe gum disease is linked to a small increase in heart attack and stroke risk, but experts say we lack proof that treating your gums will…
Frontiers
Apr 19, 2026
Radiology & Imaging
RCT
Anodized versus machined implant abutments: histologic signs of improved peri-implant soft tissue healing
New Dental Surface Tech Protects Gums Better
This histologic study compared anodized and machined custom healing abutments placed on 28 dental implants after osseointegration.
New dental implant surfaces with anodized treatment protect gums from inflammation better than standard machined metal options.
Apr 16, 2026
Infectious Disease
Sys. Review
Mini-review examines nanomaterial strategies for managing implant-associated oral biofilms
Tiny Coatings May Solve Dental Implants' Biggest Long-Term Threat
A mini-review describes multifunctional nanomaterial-based strategies for controlling peri-implantitis and oral biofilm infections, where co…
A new generation of nanomaterial-based dental implant coatings may help fight the bacterial films that cause one of the most common reasons …
Frontiers
Apr 13, 2026
Questions about Periodontal Disease
What is the link between Periodontal Disease and Alzheimer's disease risk?
Periodontal disease is linked to a higher risk of Alzheimer's disease, likely through inflammation and oral bacteria reaching the brain, but a direct cause is not proven.
Full answer →Is there a link between Periodontal Disease and pancreatic cancer in older adults?
Yes, research suggests periodontal disease is linked to a higher risk of pancreatic cancer in older adults, possibly due to chronic inflammation and oral bacteria.
Full answer →