HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.
Infectious Disease
Sys. Review
Magnesium phosphate cements demonstrate superior biological interactions and faster resorption than calcium phosphate cements
Magnesium Phosphate Cements Show Better Biological Interaction Than Calcium Options
This mini review examines the properties of magnesium phosphate cements (MPCs) compared to calcium phosphate cements (CPCs). The authors con…
New research suggests magnesium phosphate cements may offer better biological interactions and faster resorption than traditional calcium ph…
Frontiers
Jul 18, 2026
Gastroenterology
Sys. Review
Physical exercise may attenuate inflammation and alveolar bone loss in patients with periodontitis
Exercise May Help Reduce Inflammation and Bone Loss in Periodontitis
This scoping review of 23 studies examines the impact of physical exercise on inflammation and alveolar bone loss in humans and rodents. The…
New research suggests that regular physical exercise may help reduce inflammation and bone loss for people living with gum disease.
Frontiers
Jul 16, 2026
Gastroenterology
Sys. Review
Oral diseases stem from disrupted host-microbiome-immune balance, narrative review argues
New research explores how oral bacteria drive gum disease
This narrative review argues that periodontitis, dental caries, and oral squamous cell carcinoma should be understood as disorders of host-m…
Oral health depends on a delicate balance between your immune system, tissue barriers, and the trillions of microbes living in your mouth.
Frontiers
Jun 22, 2026
Infectious Disease
Sys. Review
Plant essential oils demonstrate significant inhibitory effects against key subgingival plaque microbial complexes in periodontitis
Plant essential oils show promise against gum disease bacteria
This systematic review synthesizes the antibacterial activity of plant essential oils, including carvacrol and thymol, against subgingival p…
Certain plant oils may fight the specific bacteria that cause periodontitis while also helping to block harmful biofilm from forming in the …
Frontiers
Jun 10, 2026
Neurology
Sys. Review
Advanced experimental models and computational tools provide dynamic frameworks for understanding oral disease progression
New Research Tools Help Map Complex Oral Diseases
This mini-review examines the integration of advanced experimental models, such as organ-on-chip systems and patient-derived organoids, with…
Advanced modeling and AI tools are helping researchers better understand the molecular causes behind conditions like gum disease and oral ca…
Frontiers
Jun 9, 2026
Neurology
Meta-analysis
Periodontal disease is associated with a 2.67 odds ratio for Alzheimer's disease
Gum disease linked to higher Alzheimer's risk in large analysis
This meta-analysis of 291,057 participants identified a significant association between periodontal disease and Alzheimer's disease (OR = 2.…
A large analysis of 291,057 people found that gum disease is linked to nearly 3 times higher odds of Alzheimer's disease, but more research …
Jun 7, 2026
Allergy & Immunology
Sys. Review
Periodontitis and chronic liver disease linked through proposed oral-gut-liver axis
Conceptual framework links liver, gut, immune, and oral health
This narrative review proposes a Liver-Gut-Immune-Oral Axis linking periodontitis and chronic liver disease. The authors synthesize mechanis…
A narrative review suggests a conceptual link between liver disease and oral health, though this biological system needs direct experimental…
Frontiers
Jun 4, 2026
Physical Medicine & Rehab
Meta-analysis
Meta-analysis of 16 trials shows no added benefit of subgingival chemical irrigation for periodontitis
Deep cleaning your gums? That extra rinse may not help at all
This systematic review and meta-analysis evaluated 16 randomized clinical trials comparing subgingival irrigation with chemical agents versu…
If you have gum disease and your dentist suggests a special rinse during a deep cleaning, new research says it probably won't make a differe…
May 13, 2026
Gastroenterology
Sys. Review
Narrative review of oxidative stress and antioxidant defense in periodontitis and peri-implantitis
Oxidative stress may drive gum disease and bone loss
This narrative review examines the role of oxidative stress and antioxidant defense systems in periodontitis and peri-implantitis.
New evidence suggests that an imbalance in your body's antioxidant defenses could play a major role in how gum disease progresses.
Frontiers
Apr 30, 2026
Gastroenterology
Sys. Review
Narrative review examines links between periodontitis and systemic disorders without claiming causation
Oral inflammation may link to systemic disorders, but evidence is not definitive
This narrative review explores the relationship between oral inflammatory diseases, particularly periodontitis, and various systemic disorde…
A narrative review suggests oral inflammatory diseases like periodontitis are associated with systemic disorders, though the evidence is not…
Frontiers
Apr 29, 2026
Diabetes & Endocrinology
Cohort
Narrative review offers theoretical framework for precision interventions in periodontitis and peri-implantitis based on the neuro-osteo-immune axis
1. HEADLINE
This narrative review provides a theoretical framework for future precision interventions in oral inflammatory diseases based on the neuro-o…
Nerves explain why implants lose bone faster than
Frontiers
Apr 29, 2026
Gastroenterology
Cohort
Oral microbiome profiles differ by periodontitis stage in Korean adults
Gum disease severity linked to specific oral bacteria in Korean adults
This pilot prospective cross-sectional study of 74 Korean adults assessed oral microbiome profiles by periodontitis stage.
Severe gum disease in Korean adults shows a unique bacterial pattern, pointing to future microbiome-based diagnostic tools.
Frontiers
Apr 27, 2026
Questions about Periodontal Disease
What is the link between Periodontal Disease and Alzheimer's disease risk?
Periodontal disease is linked to a higher risk of Alzheimer's disease, likely through inflammation and oral bacteria reaching the brain, but a direct cause is not proven.
Full answer →Is there a link between Periodontal Disease and pancreatic cancer in older adults?
Yes, research suggests periodontal disease is linked to a higher risk of pancreatic cancer in older adults, possibly due to chronic inflammation and oral bacteria.
Full answer →