Indoor residual spraying linked to over 70% reduction in malaria force of infection in Ghanaian children
A Clever Math Trick Just Measured Malaria Where Surveys Can't Reach
A cohort study in 1-5-year-old children in northern Ghana estimated malaria transmission using queuing theory approaches.
Borrowing math from call-center lines may help scientists prove whether malaria sprays actually work.
Ultra-sensitive PCR on residual DBS shows 7.7% P. falciparum prevalence in Rwandan adults
A Hidden Malaria Surge is Hiding in Plain Sight. Here’s the Truth
This observational cross-sectional analysis examined residual dried blood spots from the 2019-20 Demographic and Health Surveys in Rwanda.
A new way of testing shows malaria is both more common and declining faster in Rwanda than we thought, offering a clearer map to finally bea…
Research across Malaria
Related studies from across the Malaria family.
Pfkelch13 mutations occur in 6% of Plasmodium falciparum isolates across various African regions
New Data Shows Regional Differences in Malaria Drug Resistance
This meta-analysis of observational cohort studies evaluates the prevalence of pfkelch13 mutations in Plasmodium falciparum isolates from pa…
New research reveals varying levels of a specific genetic mutation that may link to reduced effectiveness of malaria treatments across Afric…
Malaria vaccines RTS,S/AS01 and R21/Matrix-M reduce malaria risk in children
Malaria vaccines cut risk by 23% in infants, 39% in toddlers
This systematic review and meta-analysis of 8 studies found that RTS,S/AS01 and R21/Matrix-M vaccines reduce malaria risk in children. In th…
Two malaria vaccines, RTS,S and R21, reduce malaria risk by 23% in young infants and 39% in older children, a review finds.
One in six blood donors in Cameroon carries Plasmodium infection, meta-analysis finds
1 in 6 blood donors in Cameroon carries malaria parasite
A systematic review and meta-analysis of 18 studies (~12,500 donations) found a 16.6% pooled prevalence of Plasmodium spp. in Cameroonian bl…
A review of 18 studies finds 16.6% of blood donations in Cameroon contain Plasmodium, the malaria parasite.
Clinical and laboratory abnormalities linked to higher mortality in malaria patients with acute kidney injury
Severe lab changes in malaria patients with kidney injury strongly predict death
This systematic review and meta-analysis evaluated the relationship between various clinical and laboratory abnormalities and mortality in m…
Severe lab changes like low blood pressure or breathing trouble in malaria patients with kidney injury greatly increase the risk of dying.
Review of Malaria literature lacks reported data on interventions and outcomes
Review of malaria treatments shows what doctors need to know
This narrative review addresses malaria but does not report specific interventions, populations, or outcomes. The authors note that key deta…
This review of malaria treatments offers important information for doctors and patients facing this serious infection.
Narrative review links chronic hemozoin exposure to prostate cancer development in malaria regions
Malaria Byproduct May Fuel Prostate Cancer Growth
This narrative review explores the hypothesis that chronic exposure to hemozoin from malaria may contribute to prostate cancer development. …
A byproduct left behind by malaria parasites may fuel prostate cancer by keeping the immune system in a constant state of low-grade inflamma…
Iron micronutrient powders reduce malaria-induced anaemia but not growth in young children
Iron powders reduce malaria-related anaemia in young children
This cluster-randomized trial in 1,806 Ghanaian children aged 6-35 months found that daily iron-containing micronutrient powders for five mo…
Daily iron-based micronutrient powders can lower the risk of malaria-induced anaemia in preschool children in Ghana.
L9LS monoclonal antibody reduces malaria infection in children in western Kenya
A malaria shot for babies shows real protection in Kenya
This randomized controlled trial evaluated the L9LS monoclonal antibody in infants and children in a high perennial malaria transmission set…
A long-acting antibody shot reduced malaria infections by 43% in young children in Kenya, with no major safety concerns.
Narrative review outlines VLP engineering strategies for broadly protective vaccines against multiple viral pathogens
New Vaccine Map Helps Pick Best Tools
This narrative review examines virus-like particle (VLP) engineering strategies, including genetic fusion, modular conjugation, and nucleic …
Imagine trying to fix a leaky roof with every tool in the shed.
Observational cross-sectional study on environmental covariates and malaria prevalence in Tanzania
Does the grass and shrubs near your home affect malaria risk?
This observational cross-sectional study in Mainland Tanzania examined household-level environmental covariates and malaria parasite prevale…
This matters because where you live can change your family's malaria risk.
Phase Ia trial of RH5.1 protein with Matrix-M adjuvant in malaria-naive UK adults showed safety and similar immunogenicity across two booster regimens
A Malaria Vaccine Candidate Holds Strong — Even With a Smaller Booster Dose
This Phase Ia clinical trial evaluated the safety and immunogenicity of RH5.1 soluble protein with Matrix-M adjuvant in malaria-naive UK adu…
A malaria vaccine candidate produced strong immune responses even when the final booster dose was cut in half, potentially helping extend va…
Digital health technologies improve malaria vaccine adherence and data quality in African populations
Your Phone Could Be the Key to Ending Malaria in Africa
This systematic review evaluated digital health (DH) and mobile computing (mHealth) technologies in African populations.
Simple text messages and voice calls could be the missing piece to ensure new malaria vaccines protect the children who need them most.