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Pneumococcal Disease

7 published articles · Updated continuously

Clinical Trial Landscape

Clinical Trials for Pneumococcal Disease

30 trials tracked for Pneumococcal Disease: 23 in phase 3 or 4 and 16 with published results. The most-cited published study has 171 citations.

30Trials tracked
23Phase 3 & 4
0Recruiting
16With published results
Phase distribution
Phase 4 2 Phase 3 21 Phase 2 2 Phase 1 1 Other / NA 4
  1. Phase 3 Trial to Evaluate the Safety and Immunogenicity of a 20-valent Pneumococcal Conjugate Vaccine in Pneumococcal Vaccine-naïve Adults Completed · 171 cited
  2. Phase 3 Trial to Evaluate the Safety and Immunogenicity of a 20-Valent Pneumococcal Vaccine in Adults 65 Years of Age or Older With Prior Pneumococcal Vaccination Completed · 82 cited
  3. Phase 3 Trial to Evaluate the Safety and Immunogenicity of 3 Lots of 20-valent Pneumococcal Conjugate Vaccine in Pneumococcal Vaccine-Naïve Adults Completed · 77 cited
  4. Phase 3 20-valent Pneumococcal Conjugate Vaccine Safety and Immunogenicity Study of a 4-Dose Series in Healthy Infants Completed · 42 cited
  5. Phase 3 Safety and Immunogenicity of 20vPnC Coadministered With SIIV in Adults ≥65 Years of Age Completed · 28 cited
  6. Phase 3 20-valent Pneumococcal Conjugate Vaccine Safety and Immunogenicity Study of a 3-Dose Series in Healthy Infants Completed · 28 cited
Show 24 more trials
  1. Phase 3 Safety and Immunogenicity Study of 20vPnC When Coadministered With a Booster Dose of BNT162b2 Completed · 26 cited
  2. Phase 3 20-valent Pneumococcal Conjugate Vaccine Safety and Immunogenicity Study in Pneumococcal Vaccine-Naïve Adults 60 Years of Age and Older in Japan, Korea, and Taiwan Completed · 22 cited
  3. Phase 3 Safety and Immunogenicity of 20vPnC in Toddlers With 2 Prior Doses of Prevenar 13 Completed · 5 cited
  4. Phase 3 Safety and Immunogenicity of V116 in Pneumococcal Vaccine-naïve Adults 50 Years of Age or Older (V116-010, STRIDE-10) Completed · 4 cited
  5. Phase 3 20-valent Pneumococcal Conjugate Vaccine Safety and Immunogenicity Study in Healthy Japanese Infants Completed · 4 cited
  6. Phase 3 Safety and Immunogenicity of V114 in Healthy Infants in South Korea (V114-036) Completed · 2 cited
  7. Phase 3 A Study to Learn About the Safety and Immune Response of 20vPnC in Adults in India. Completed · 2 cited
  8. Phase 3 Safety and Immunogenicity of V116 in Adults Living With Human Immunodeficiency Virus (HIV) (V116-007, STRIDE-7) Completed · 1 cited
  9. Phase 3 A Study to Evaluate the Safety, Tolerability, Immunogenicity, and Lot Consistency of V116 in Adults 18 to 49 Years of Age (V116-004, STRIDE-4) Completed
  10. Phase 3 Safety and Immunogenicity of V116 in Vaccine-naïve Japanese Older Adults (V116-009, STRIDE-9) Completed
  11. Phase 4 A Study to Describe the Safety of a Vaccine (Called 13vPnC) in Healthy People 18 to 49 Years of Age in India Completed
  12. Phase 4 A Study to Assess the Antibody Response of Healthy Chinese Children Who Have Been Vaccinated Previously With 4-doses of Prevenar (a Pneumococcal Vaccine) as Babies and Toddlers Completed
  13. Phase 3 Safety and Immunogenicity Study of 20vPnC in Healthy Children 15 Months Through 17 Years of Age Completed
  14. Phase 3 20-valent Pneumococcal Conjugate Vaccine Safety Study in Healthy Infants Completed
  15. Phase 3 Study Evaluating the Impact of the 13-valent Pneumococcal Conjugate Vaccine (13vPnC) in Alaskan Native Children. Completed
  16. Phase 3 A Phase III Clinical Trial to Study the Safety and Immunogenicity of Pneumovax™ 23 (V110) in Participants From the Russian Population (V110-018) Completed
  17. Phase 3 Immune Response In Children Revaccinated With Pneumococcal Conjugate Vaccine Completed
  18. Phase 2 A Single Ascending Dose Study in Adults (Stage 1) and Single Ascending Dose-Finding Study (Stage 2) in Elderly Subjects With ASP3772, A Pneumococcal Vaccine Completed
  19. Phase 2 Safety and Immunogenicity of a 10 Valent Pneumococcal Conjugate Vaccine (SIILPCV10) in Healthy Adults, Toddlers, Infants Completed
  20. Phase 1 Safety and Immunogenicity of Pneumococcal Conjugate Formulations in Healthy Adults 18 Through 49 Years of Age Completed
  21. N/A Post Market Surveillance to Observe Safety of Prevenar13™ in Adults Completed
  22. N/A Safety Surveillance of Pneumococcal 13-valent Conjugate Vaccine Among Filipinos Completed
  23. N/A Nasopharyngeal Carriage Study in Healthy Kenyan Toddlers Completed
  24. N/A Postlicensure Observational Safety Study of 13vPnC Administered to Infants and Toddlers Completed

Showing the 30 most-cited and recently-updated of 30 trials. Browse the full registry →

Trial data sourced from ClinicalTrials.gov. Counts describe the research landscape and are not a treatment recommendation. Informational only — not medical advice.

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.

Questions about Pneumococcal Disease

Is the 21-valent pneumococcal conjugate vaccine an option for some U.S. adults?

The 21-valent pneumococcal conjugate vaccine is an approved option for some U.S. adults aged 19 and older who need protection against pneumococcal disease.

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Does the 15-valent pneumococcal conjugate vaccine work for U.S. children?

Yes, the 15-valent pneumococcal conjugate vaccine (PCV15) is recommended by the CDC for U.S. children aged 6 weeks to 17 years as an option for preventing pneumococcal disease.

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Which pneumococcal conjugate vaccine does ACIP recommend for U.S. children now?

The Advisory Committee on Immunization Practices (ACIP) currently recommends the 20-valent pneumococcal conjugate vaccine (PCV20) for children in the United States.

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Do vaccines protect against pneumococcal disease in sub-Saharan African children?

Research confirms that pneumococcal vaccines provide protective effects against the disease in children living in sub-Saharan Africa.

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