Research across Tuberculosis
Related studies from across the Tuberculosis family.
Tuberculosis prevalence among children with severe acute malnutrition is 13% (95% CI: 11-16%)
Tuberculosis is common among children with severe acute malnutrition
This meta-analysis of 33,869 children across 15 countries identifies a pooled tuberculosis prevalence of 13% in those with severe acute maln…
Over 13% of children suffering from severe acute malnutrition also have tuberculosis, highlighting a critical need for integrated screening.
WGS-based tools provide high specificity and sensitivity for rifampicin, isoniazid, and fluoroquinolone resistance detection
New tools help doctors identify drug resistant tuberculosis strains
This meta-analysis of 144,623 M. tuberculosis genomes evaluates six open-access WGS-based drug susceptibility testing prediction tools. The …
New computer tools can accurately predict if common drugs will work against tuberculosis, helping doctors choose the right treatment faster.
Pulmonary TB History Linked to Higher COPD Odds
Past tuberculosis infection significantly increases risk of developing lung disease
Meta-analysis of over 1 million people finds prior pulmonary TB associated with 2.65 times higher odds of COPD.
A history of pulmonary tuberculosis is linked to a much higher risk of developing chronic obstructive pulmonary disease, especially in certa…
TB-TST mobile application increases treatment success to 82% in drug susceptible tuberculosis
Mobile App Improves Success Rates for Tuberculosis Treatment
This pragmatic randomized controlled trial of 555 individuals with newly diagnosed drug susceptible tuberculosis found that the TB-TST inter…
A mobile app and urine tests helped more patients complete their tuberculosis treatment compared to standard care alone.
Modified regimens for drug-resistant tuberculosis show higher success rates than standard regimens in Cameroon
Modified drug regimens show higher success for drug-resistant tuberculosis
This systematic review and meta-analysis of 2,351 patients with drug-resistant tuberculosis (DR-TB) in Cameroon found that modified regimens…
A new analysis shows modified treatment plans can improve success rates for patients fighting drug-resistant tuberculosis.
Baseline auramine count predicts tuberculosis failure or relapse by 5% higher odds per 100 bacilli
Auramine Levels May Predict Treatment Success for Tuberculosis Patients
This secondary analysis of an RCT involving 321 patients treated with double-dose R. found that quantitative baseline auramine significantly…
A study suggests that specific bacteria counts at the start of treatment can help predict if a patient with tuberculosis will experience a r…
HIV co-infection triples MDR-TB mortality risk; low BMI and anaemia also raise risk
HIV and other risk factors linked to multidrug-resistant tuberculosis deaths
This meta-analysis of 36,693 patients with multidrug-resistant tuberculosis (MDR-TB) found that HIV co-infection, lower educational attainme…
Patients with multidrug-resistant tuberculosis face higher risks of death if they also have HIV, low body mass index, or certain other healt…
Rifapentine 15 mg/kg and 20 mg/kg yield higher culture conversion than standard 6-month regimen
Trial Shows Rifapentine Dosage Impacts Tuberculosis Treatment Outcomes
This Phase 2/3 Stage 1 randomized controlled trial of 400 adults with pulmonary drug-susceptible tuberculosis compared three 4-month rifapen…
A new clinical trial explores how different doses of rifapentine affect treatment success and safety for patients with drug-susceptible tube…
Shorter rifamycin-containing regimens show comparable efficacy to longer isoniazid monotherapy for latent tuberculosis infection
Shorter drug plans may help children finish tuberculosis treatments
This meta-analysis evaluated shorter rifamycin-containing regimens against a nine-month isoniazid course in children with latent tuberculosi…
New data suggests shorter treatment plans for latent tuberculosis can help children complete their medication without increasing the risk of…
Multidrug-resistant tuberculosis prevalence is 5.2% among patients with bacteriologically confirmed cases in Cameroon
Identifying key risks for drug resistant tuberculosis infections in Cameroon
This meta-analysis of 28 studies involving 9,931 patients identifies a 5.2% pooled prevalence of multidrug-resistant tuberculosis (MDR-TB) i…
New data shows that past infections and lifestyle factors like alcohol use can increase the risk of developing hard-to-treat tuberculosis.
Respiratory viral coinfections reshape immune signaling and granuloma stability in Mycobacterium tuberculosis infections
Viral Infections May Change How the Body Fights Tuberculosis
This narrative review synthesizes how respiratory viruses, including SARS-CoV-2 and influenza, impact host immune signaling and granuloma eq…
Research shows that common respiratory viruses like flu or COVID-19 can change how the immune system responds to tuberculosis infections.
6-month bedaquiline, linezolid, delamanid, and levofloxacin or clofazimine regimen is noninferior to 9-month standard care
Trial shows shorter treatment works for resistant tuberculosis
This Phase 3 randomized controlled noninferiority trial evaluated a 6-month treatment strategy for pulmonary rifampicin-resistant tuberculos…
A new six-month treatment plan for drug-resistant tuberculosis showed similar success rates to the standard nine-month course.