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Psychiatry
Meta-analysis
Preoperative psychological factors are associated with postoperative cognitive outcomes in older adults.
Psychological factors linked to cognitive issues after surgery in older adults
This systematic review and meta-analysis examined preoperative psychological factors in older adults aged 60 years or older. The analysis in…
A large review links preoperative anxiety and stress to worse cognitive outcomes after surgery for older patients.
May 1, 2026
Rheumatology
Meta-analysis
Meta-analysis identifies risk factors for postoperative delirium in oral and maxillofacial surgery patients.
Five Things Linked to Confusion After Oral and Jaw Surgery
This meta-analysis synthesizes data from 2,398 patients undergoing oral and maxillofacial surgery to identify risk factors for postoperative…
Five specific habits and traits significantly raise the risk of postoperative confusion after oral and jaw surgery procedures.
Frontiers
Apr 28, 2026
Psychiatry
Meta-analysis
Meta-analysis links low Geriatric Nutritional Risk Index to postoperative delirium risk
Low Nutrition Risk Linked to Higher Delirium After Surgery
This meta-analysis of 12,332 surgical patients found that a low Geriatric Nutritional Risk Index (GNRI) is associated with a significantly i…
Surgical patients with lower nutritional scores faced a significantly higher risk of developing delirium after their operations.
Frontiers
Apr 23, 2026
Drug Pipeline
RCT
Phase 2 RCT of IV CN-105 in older adults undergoing noncardiac surgery shows fewer grade 2+ adverse events versus placebo.
Could a simple IV drug help older adults avoid confusion after surgery?
This Phase 2 randomized clinical trial enrolled 203 older adults (60 years or older) scheduled for noncardiac or nonintracranial surgery. Pa…
A new IV drug given before surgery reduced confusion and side effects in older adults, though more testing is needed to confirm it truly pre…
Apr 17, 2026
Rheumatology
RCT
Electroacupuncture protocol aims to prevent postoperative delirium in elderly prostatectomy patients
Can acupuncture before prostate surgery help prevent confusion in older patients?
A double-center randomized controlled trial protocol outlines a study of electroacupuncture versus sham for preventing postoperative deliriu…
A new trial will test if electroacupuncture before prostate surgery can prevent postoperative delirium, a common and serious confusion in ol…
Frontiers
Apr 2, 2026
Psychiatry
Cohort
GBM model predicts postoperative delirium in elderly CHD patients with 0.856 AUC
Can a computer model predict post-surgery confusion in older heart patients? A new tool shows promise.
A retrospective cohort study of 861 elderly patients with coronary heart disease (CHD) undergoing non-cardiac surgery developed a gradient b…
A new computer tool predicts post-surgery confusion in older heart patients by analyzing frailty, memory, and sleep patterns to help doctors…
Frontiers
Mar 30, 2026