Programmed cell death pathways form a spatiotemporally regulated network driving tubular damage in renal IRI
New research identifies key pathways driving acute kidney injury
This systematic review examines the roles of pyroptosis, ferroptosis, cuproptosis, and necroptosis as key mediators of inflammation and oxid…
Researchers have mapped out a complex network of cell death pathways that drive inflammation and damage in patients with acute kidney injury…
Narrative review discusses exosomes for renal ischemia-reperfusion injury management and translational barriers
Tiny Kidney Protectors May Shield Patients From Sudden Damage
This narrative review examines the potential of exosomes for managing renal ischemia-reperfusion injury. The authors discuss the scope of th…
• Exosomes might prevent kidney harm when blood flow returns • Helps surgery patients and trauma survivors avoid kidney failure • Still in l…
Research across Kidney Diseases
Related studies from across the Kidney Diseases family.
Astragaloside IV significantly reduces renal fibrosis markers and serum creatinine in preclinical animal models
Astragaloside IV Shows Potential for Treating Chronic Kidney Disease
This meta-analysis of preclinical animal studies indicates that Astragaloside IV significantly reduces serum creatinine, blood urea nitrogen…
Early research in animal models suggests that Astragaloside IV may reduce key markers of kidney damage and fibrosis in chronic kidney diseas…
Flexible aspiration navigable sheaths increase 30-day stone-free rates for renal calculi under 2 cm
Suction-Assisted Tools Show Higher Success for Small Kidney Stones
This systematic review and Bayesian network meta-analysis of 3657 patients found that flexible aspiration navigable sheaths (FANS) significa…
New analysis suggests that using specific suction-assisted tools can improve stone-free rates and reduce complications for patients with sma…
Tubeless percutaneous nephrolithotomy reduces hospital stay and analgesic use compared to standard percutaneous nephrolithotomy
Tubeless Surgery May Reduce Pain and Recovery Time for Kidney Stones
This meta-analysis of randomized controlled trials involving 2171 patients with large and complex renal calculi found that tubeless percutan…
A tubeless surgical technique for large kidney stones may lead to less pain and shorter hospital stays compared to standard methods.
Yupingfeng powder demonstrates multi-functional pharmacological activities and clinical benefits in various renal diseases
Yupingfeng powder shows potential to manage symptoms of kidney disease
This systematic review examines the pharmacological properties and clinical impacts of Yupingfeng powder (YPFP) on renal diseases. The autho…
A new look at Yupingfeng powder reveals it may help slow the progression of kidney diseases and ease related symptoms.
Environmental cadmium exposure may cause male reproductive dysfunction through the renal-testis axis
Cadmium exposure may harm male fertility and kidney health
This narrative review of 40 animal studies synthesizes evidence on environmental cadmium exposure and its impact on male reproduction. The a…
Environmental cadmium exposure can damage the male reproductive system and kidneys, potentially leading to lower semen quality and other iss…
Gut microbiota dysbiosis and microbial metabolites impair renal function in sepsis-associated acute kidney injury
Sepsis may damage kidneys by letting gut bacteria toxins leak into the blood
This narrative review examines the role of gut microbiota dysbiosis in sepsis-associated acute kidney injury and acute kidney injury. The au…
A review suggests that sepsis changes gut bacteria, causing harmful toxins to leak and hurt kidneys in humans and animals.
Fluoroless ultrasound-guided techniques lower complications in percutaneous nephrolithotomy with equivalent stone-free rates
Fluoroless ultrasound guidance reduces complications during kidney stone surgery
This systematic review and meta-analysis of randomized studies evaluated fluoroless ultrasound-guided versus fluoroscopy-guided techniques f…
A meta-analysis of randomized trials shows that using ultrasound instead of X-ray guidance lowers overall complications for kidney stone rem…
Model-informed precision dosing improves vancomycin target attainment in critically ill children compared to standard therapeutic drug monitoring
New dosing model helps severely ill children hit drug targets faster
In critically ill children, model-informed precision dosing significantly improved vancomycin target attainment versus standard monitoring. …
A new dosing method helped more critically ill children reach the right drug levels in their blood within two days of starting treatment for…
Meta-analysis of RCTs shows mPCNL yields higher single-session stone-free rates than RIRS for medium renal stones
Mini-PCNL clears kidney stones better than RIRS in one session
This meta-analysis of randomized controlled trials evaluated retrograde intrarenal surgery versus miniaturized percutaneous nephrolithotomy …
Mini-PCNL clears medium-sized kidney stones in one session more often than RIRS, but RIRS has fewer complications and shorter hospital stays…
Narrative review on anthracycline cardiorenal toxicity and dexrazoxane protection
Doctors seek better ways to protect heart and kidney health during cancer drug treatment
This narrative review synthesizes evidence on anthracycline-induced cardiorenal toxicity and dexrazoxane's protective role. The authors note…
Cancer treatments called anthracyclines can harm the heart and kidneys. This review explains why doctors need new strategies to keep patient…
Meta-analysis links suprarenal aortic repair techniques to higher risk of permanent renal dialysis in AAA patients
Large review shows kidney dialysis risk is higher when surgeons clamp above the kidney during aortic repair
This systematic review and meta-analysis evaluated the risk of permanent renal dialysis following various abdominal aortic aneurysm repair t…
A big study looked at over 72,000 patients having surgery for a bulging aorta. It found that operations touching the kidney area make kidney…
Narrative review on renal involvement in primary Sjögren's disease and therapeutic prospects
Understanding kidney problems in primary Sjogren's disease patients needs more research
This narrative review synthesizes current knowledge on renal involvement in primary Sjögren's disease. It highlights that the pathogenic bas…
Doctors are still learning how kidneys get hurt in primary Sjogren's disease. Current treatments work by guesswork because the exact cause i…