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Genetics & Precision Medicine
Meta-analysis
Meta-analysis identifies ancestry-specific and shared genetic loci for restless legs syndrome in diverse populations
Genetic study finds new risk factors for restless legs syndrome in diverse populations
This meta-analysis examines genome-wide association data from biobank-based cohorts involving African, Latin American, and European ancestry…
A large genetic study reveals new risk factors for restless legs syndrome in African, Latin American, and European ancestry groups.
medRxiv
Apr 30, 2026
Neurology
Cohort
Machine learning model identifies RLS in ESRD patients with AUC 0.791
Machine learning model helps identify restless legs in dialysis patients
This cohort study of 396 end-stage renal disease patients undergoing dialysis developed a machine learning classification model to identify …
A new machine learning model shows promise for spotting restless legs syndrome in people with end-stage kidney disease undergoing dialysis.
Frontiers
Apr 29, 2026
OB/GYN & Women's Health
Review finds bed partners have more sleep apnea than pregnant co-sleepers in third trimester
Pregnant women sleep better than their partners despite restlessness
This review of an observational study examined sleep physiology in 41 pregnant participants and 36 bed partners. Bed partners had significan…
Healthy pregnant women sleep better than their bed partners, who face a much higher risk of severe sleep apnea during this time.
medRxiv
Apr 26, 2026
Anesthesiology & Pain Medicine
RCT
Two-week active tsDCS improved RLS symptoms and neurophysiological measures versus sham in a small RCT.
Could a two-week treatment ease restless legs and improve sleep for patients?
This randomized controlled trial evaluated active transcutaneous spinal cord direct current stimulation (tsDCS) versus sham stimulation in 3…
A two-week electrical stimulation treatment significantly eased restless legs symptoms and improved sleep quality compared to a fake treatme…
Apr 6, 2026