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Home › Conditions › sexual dysfunction

Sexual dysfunction

0 published articles · Updated continuously

Clinical Trial Landscape

Clinical Trials for sexual dysfunction

19 trials tracked for sexual dysfunction: 6 in phase 3 or 4 and 3 with published results. The most-cited published study has 62 citations.

19Trials tracked
6Phase 3 & 4
0Recruiting
3With published results
Phase distribution
Phase 3 6 Phase 2 1 Phase 1 1 Other / NA 11
  1. Phase 3 Tadalafil in Preventing Erectile Dysfunction in Patients With Prostate Cancer Treated With Radiation Therapy Completed · 62 cited
  2. Phase 3 Impact of Lactate-Containing Vaginal Lubricant on Sexual Dysfunction in Young Breast Cancer Survivors Completed · 15 cited
  3. Phase 3 Testosterone in Treating Postmenopausal Patients With Arthralgia Caused by Adjuvant Aromatase Inhibitor Treatment Completed · 14 cited
  4. Phase 3 Safety and Effectiveness Study of Maca Root to Treat Antidepressant-Induced Sexual Dysfunction Completed
  5. Phase 3 Botulinum Toxin for Erectile Dysfunction Completed
  6. Phase 3 Concomitant Use of PriLigy in Men Treated for Erectile Dysfunction Completed
Show 13 more trials
  1. Phase 2 Radiation Therapy in Treating Patients With Prostate Cancer Completed
  2. Phase 1 Study to Investigate the Effect of AB-101 in Breast Cancer Survivors Completed
  3. N/A Intensity-Modulated Radiation Therapy With or Without Decreased Radiation Dose to Erectile Tissue in Treating Patients With Stage II Prostate Cancer Completed
  4. N/A A Multimodal Intervention to Address Sexual Dysfunction in Hematopoietic Stem Cell Transplant Survivors Completed
  5. N/A Characteristics of Sexual Dysfunction in Patients With Lung Cancer Completed
  6. N/A A Study to Measure the Degree and Effectiveness of the Various vSculpt Operating Modes Completed
  7. N/A Pilot Trial Evaluating Stereotactic Body Radiotherapy With Integrated Boost for Clinically Localized Prostate Cancer (RAD 1203) Completed
  8. N/A Efficacy of Pain Neuroscience Education in Genito-Pelvic Pain/Penetration Disorder. A Randomized Controlled Trial. Completed
  9. N/A A Mindfulness-based Intervention for Older Women With Low Sexual Desire Completed
  10. N/A L-Arginine Supplements in Treating Women Who Are Cancer Survivors Completed
  11. N/A Minimally Invasive Burch Colposuspension to Reduce Occult Stress Incontinence Completed
  12. N/A Reproductive Health Survivorship Care Plan Completed
  13. N/A Open Pilot Trial of a Mind-Body Sexual Well-Being Intervention for Female GI Cancer Survivors Completed

Showing the 19 most-cited and recently-updated of 19 trials. Browse the full registry →

Trial data sourced from ClinicalTrials.gov. Counts describe the research landscape and are not a treatment recommendation. Informational only — not medical advice.

What the trials found Updated — new results For clinicians

Sexual dysfunction: what the trials found

Established evidence regarding pharmacological and topical interventions shows mixed results for sexual dysfunction. Tadalafil was evaluated for maintaining spontaneous erectile function (EF) following radiation therapy, with no statistically significant difference observed between groups at 28-30 weeks 2 or at the 1-year and 2-year marks 2. Additionally, testosterone administration showed no statistically significant change in average pain scores from baseline to three months 4 or six months 4.

Other interventions demonstrated specific improvements: Maca Root was associated with a statistically significant reduction in Massachusetts General Hospital Sexual Dysfunction Inventory scores 6. A lactate-containing vaginal lubricant resulted in changes to the Female Sexual Function Index (FSFI) pain score and various domains of the FSFI 3. Botulinum Toxin Type A was evaluated for sexual dysfunction, though specific comparative efficacy data were not provided beyond post-treatment SHIM scores 5.

Recent results — preliminary, needs further review

  • * Systemic oncological treatment 1 * Mind-Body Group Intervention 10 * Laparoscopic Burch Colposuspension 11

For the clinician treating this condition

  • Tadalafil did not show a statistically significant impact on the maintenance of spontaneous erectile function in patients undergoing radiation therapy over a 2-year period 2.
  • Maca Root is associated with improved scores on the Massachusetts General Hospital Sexual Dysfunction Inventory 6.
  • Lactate-containing vaginal lubricants resulted in measurable changes to pain scores and multiple domains of the Female Sexual Function Index 3.

AI synthesis of 8 cited trials, updated Jun 29, 2026. Informational only — not medical advice; trial data sourced from ClinicalTrials.gov. How we use AI.

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.
No published articles yet for this condition. Check back soon.