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Home › Conditions › Sleep Disturbances

Sleep Disturbances

5 published articles · Updated continuously

Clinical Trial Landscape

Clinical Trials for Sleep Disturbances

27 trials tracked for Sleep Disturbances: 5 in phase 3 or 4.

27Trials tracked
5Phase 3 & 4
0Recruiting
0With published results
Phase distribution
Phase 4 3 Phase 3 2 Phase 2 1 Phase 1 1 Other / NA 20
  1. Phase 4 Treating Disrupted Sleep in Individuals With Inflammatory Bowel Disease Completed
  2. Phase 4 Improving Sleep Quality in Heart Failure Completed
  3. Phase 4 Efficacy and Tolerability of Combination Varenicline With Hydroxyzine as a Potential Smoking Cessation Treatment Completed
  4. Phase 3 The Efficacy of Suvorexant in Treatment of Patients With Substance Use Disorder and Insomnia: A Pilot Open Trial Completed
  5. Phase 3 Study of Brexpiprazole as Adjunctive Treatment of Sleep Disturbances in Patients With Major Depressive Disorder Completed
  6. Phase 2 Medical Management of Sleep Disturbance During Opioid Tapering Completed
Show 21 more trials
  1. Phase 1 Feasibility Study of Personalized Trials to Improve Sleep Quality Completed
  2. N/A Feasibility of Bright Light Therapy on Fatigue, Sleep and Circadian Activity Rhythms in Lung Cancer Survivors Completed
  3. N/A Behavioral Sleep Intervention in Urban Primary Care: Aim 3 Completed
  4. N/A Sleep Disruption in New Mothers: An Intervention Trial Completed
  5. N/A Stepped-Care Telehealth for Distress in Cancer Survivors Completed
  6. N/A Individually Tailored Lighting System to Improve Sleep in Older Adults Completed
  7. N/A The SleepWell Study - Chronotherapeutic Intervention to Improve Sleep Following ACS Completed
  8. N/A Sleep, Hypertension, and Nocturia: a Multicomponent Approach for Comorbid Illnesses Completed
  9. N/A Implementing Behavioral Sleep Intervention in Urban Primary Care Completed
  10. N/A Telehealth Delivery of Treatment for Sleep Disturbances in Young Children With Autism Spectrum Disorder Completed
  11. N/A A SMART Design to Improve Sleep Disturbance in Adolescents With Neurodevelopmental Disorders Completed
  12. N/A Providing Mental Health Precision Treatment Completed
  13. N/A Remote Guided Caffeine Reduction Completed
  14. N/A Developing and Testing a Spanish-Language Intervention to Reduce Cancer-Related Sleep Disturbance Completed
  15. N/A Enhancing Sleep Quality for Nursing Home Residents With Dementia Completed
  16. N/A Anxiety Lowering and Deprescribing Through Emotion Regulation Completed
  17. N/A Targeting Worry to Improve Sleep Completed
  18. N/A A Study of MUSE Device for Midlife Women Completed
  19. N/A Frequen-ZZZ SleepPad Investigational Device POC Completed
  20. N/A Personalized Integrated Chronotherapy for Perinatal Depression Completed
  21. N/A Risk of Mental Health Conditions in Children and Young Adults With Inflammatory Bowel Disease and Influence on Health Completed

Showing the 27 most-cited and recently-updated of 27 trials. Browse the full registry →

Trial data sourced from ClinicalTrials.gov. Counts describe the research landscape and are not a treatment recommendation. Informational only — not medical advice.

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.
Meta-analysis finds probiotics modestly improve sleep quality with low certainty
Neurology Meta-analysis
Meta-analysis finds probiotics modestly improve sleep quality with low certainty Probiotics may modestly improve sleep quality, review finds
This meta-analysis of 39 trials (4094 participants) found that probiotic supplementation modestly improved global sleep quality (MD -0.71 on…
A meta-analysis of 39 trials found probiotics slightly improved sleep quality and daytime function, but effects were small and evidence unce…
Frontiers May 23, 2026
Study protocol outlines randomized trial of 40 Hz auditory stimulation for postoperative sleep disturbance
Rheumatology RCT
Study protocol outlines randomized trial of 40 Hz auditory stimulation for postoperative sleep disturbance Could quiet headphones help patients sleep better after gynecological surgery?
This document describes a protocol for a randomized controlled trial involving 342 patients scheduled for laparoscopic gynecological surgery…
A new trial will test if playing a 40 Hz sound during gynecological surgery helps patients sleep better the first night after the operation.
Frontiers Apr 16, 2026
Meta-analysis of Stellate Ganglion Block shows improved sleep metrics in patients with sleep disturbances
Psychiatry Meta-analysis
Meta-analysis of Stellate Ganglion Block shows improved sleep metrics in patients with sleep disturbances Could a simple nerve block help you sleep longer and deeper?
This systematic review and meta-analysis evaluated seven studies involving patients who received a Stellate Ganglion Block (SGB) compared to…
Patients receiving a nerve block in the neck slept longer, fell asleep faster, and enjoyed deeper rest compared to those who did not receive…
Frontiers Apr 6, 2026
Multi-component environmental control intervention shows feasibility for sleep promotion in ventilated ICU patients
Emergency Medicine RCT
Multi-component environmental control intervention shows feasibility for sleep promotion in ventilated ICU patients Small pilot study tests sleep environment intervention for ventilated ICU patients
A pilot randomized controlled trial in 17 mechanically ventilated ICU patients with minimal sedation assessed the feasibility of a multi-com…
A small Chilean ICU study shows that dynamic lights, sound masking, and grouped care checks are feasible ways to help ventilated patients sl…
Apr 4, 2026
Progressive Muscle Relaxation May Reduce Pain and Improve Sleep After Open Heart Surgery
Anesthesiology & Pain Medicine RCT
Progressive Muscle Relaxation May Reduce Pain and Improve Sleep After Open Heart Surgery Relaxation technique may help reduce pain and improve sleep after heart surgery
A single-center, single-blind RCT of 60 patients undergoing open heart surgery found that twice-daily Progressive Muscle Relaxation (PMR) on…
A simple relaxation technique helped heart surgery patients cut pain from a 9 out of 10 to just 1.5 and sleep better within three days.
Apr 3, 2026